National Healthcare Quality and Disparities Report
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- (-) Substance Abuse (44)
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- Vulnerable Populations (2)
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- Young Adults (3)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 25 of 44 Research Studies DisplayedChan B, Freeman M, Ayers C
A systematic review and meta-analysis of medications for stimulant use disorders in patients with co-occurring opioid use disorders.
This systematic review and meta-analysis looked at medication efficacy for stimulant use disorders in patients with co-occurring opioid use disorders. Multiple databases were searched through April 2019 for randomized controlled trials, and dual-screened studies using pre-specified inclusion criteria. Thirty-four trials of 22 medications focused on cocaine use disorder in patients with opioid use disorder. Most studies used methadone treatment for patients with opioid use disorder. Primary outcomes were abstinence, defined as stimulant-negative urine for three or more consecutive weeks. However, none of the six studies that assessed abstinence found significant differences among groups. The authors found moderate strength evidence that antidepressants and disulfiram worsened treatment retention. There was low-strength evidence that psychostimulants reduced cocaine use. There was only 1 trial for methamphetamine use disorder which had insufficient strength evidence for naltrexone.
AHRQ-funded; HS022981.
Citation: Chan B, Freeman M, Ayers C .
A systematic review and meta-analysis of medications for stimulant use disorders in patients with co-occurring opioid use disorders.
Drug Alcohol Depend 2020 Nov 1;216:108193. doi: 10.1016/j.drugalcdep.2020.108193..
Keywords: Opioids, Substance Abuse, Medication, Evidence-Based Practice
Matson TE, Lapham GT, Bobb
Cannabis use, other drug use, and risk of subsequent acute care in primary care patients.
This study evaluated whether self-reported frequency of cannabis or other drug use was associated with subsequent acute care. Using EHR and claims data from 8 sites in Washington State that implemented annual substance use screening, findings showed that those reporting cannabis use less than monthly or daily had greater risk of acute care during follow-up than those reporting no use. Patients reporting other drug use less than monthly, weekly, or daily had greater risk of acute care than those reporting no other drug use. It is unclear whether findings will generalize to U.S. states with broader racial/ethnic diversity.
AHRQ-funded; HS023173.
Citation: Matson TE, Lapham GT, Bobb .
Cannabis use, other drug use, and risk of subsequent acute care in primary care patients.
Drug Alcohol Depend 2020 Nov 1;216:108227. doi: 10.1016/j.drugalcdep.2020.108227..
Keywords: Substance Abuse, Primary Care, Emergency Department
Yang J, Landrum MB, Zhou L
Disparities in outpatient visits for mental health and/or substance use disorders during the COVID surge and partial reopening in Massachusetts.
The purpose of this study was to examine changes in outpatient visits for mental health and/or substance use disorders (MH/SUD) in an integrated healthcare organization during the initial Massachusetts COVID-19 surge and partial state reopening. The investigators concluded that MH/SUD visit volume increased during the COVID surge and was supported by rapidly-scaled telemedicine.
AHRQ-funded; HS025375.
Citation: Yang J, Landrum MB, Zhou L .
Disparities in outpatient visits for mental health and/or substance use disorders during the COVID surge and partial reopening in Massachusetts.
Gen Hosp Psychiatry 2020 Nov-Dec;67:100-06. doi: 10.1016/j.genhosppsych.2020.09.004..
Keywords: Behavioral Health, Substance Abuse, COVID-19, Disparities, Access to Care, Ambulatory Care and Surgery, Telehealth, Health Information Technology (HIT)
Althoff KN, Leifheit KM, Park JN
Opioid-related overdose mortality in the era of fentanyl: monitoring a shifting epidemic by person, place, and time.
Investigators described US trends in opioid-related overdose mortality rates by race, age, urbanicity, and opioid type before and after the emergence of fentanyl. Using the CDC’s WONDER database, they found a disproportionate increase in opioid-related overdose deaths among urban non-Hispanic Black Americans and recommended interventions for this population in order to halt the increase in overdose deaths.
AHRQ-funded; HS000046.
Citation: Althoff KN, Leifheit KM, Park JN .
Opioid-related overdose mortality in the era of fentanyl: monitoring a shifting epidemic by person, place, and time.
Drug Alcohol Depend 2020 Nov 1;216:108321. doi: 10.1016/j.drugalcdep.2020.108321..
Keywords: Opioids, Medication, Substance Abuse, Mortality, Racial and Ethnic Minorities, Social Determinants of Health
Dir AL, Clifton RL
Patterns of drug screen results and court-ordered substance use treatment referrals and completion among justice-involved youth
This study examined court records of drug screens among youth to explore patterns of substance use as well as rates of court-ordered referral to substance use treatment and treatment completion. Of the studied youth with a positive oral drug screen, 96% tested positive for cannabis and 9.8% for opioids at least once; 48.5% were court-ordered to substance use treatment. Of those referred, 67% had history of completing at least one treatment episode. These results underscore the need to utilize objective measures as well as validated self-reports of substance use history in both research and justice system decision-making to aid in identifying youth in need of services.
AHRQ-funded; HS022681; HS023318.
Citation: Dir AL, Clifton RL .
Patterns of drug screen results and court-ordered substance use treatment referrals and completion among justice-involved youth
J Subst Abuse Treat 2020 Nov;118:108095. doi: 10.1016/j.jsat.2020.108095..
Keywords: Children/Adolescents, Substance Abuse, Screening, Vulnerable Populations
Kolak MA, Chen YT, Joyce S
Rural risk environments, opioid-related overdose, and infectious diseases: a multidimensional, spatial perspective.
The authors adapted a risk environment framework to characterize rural southern Illinois and to describe the relations of risk environments, opioid-related overdose, HIV, Hepatitis C, and sexually transmitted infection rates between 2015 and 2017. They identified pervasive risk hotspots in more populated locales with higher rates of overdose and HCV incidence, whereas emerging risk areas were isolated to more rural locales that had experienced an increase in analgesic opiate overdoses and generally lacked harm-reduction resources. They also found that at-risk areas were characterized with underlying socioeconomic vulnerability but in differing ways, reflecting a nuanced and shifting structural risk landscape.
AHRQ-funded; HS022433.
Citation: Kolak MA, Chen YT, Joyce S .
Rural risk environments, opioid-related overdose, and infectious diseases: a multidimensional, spatial perspective.
Int J Drug Policy 2020 Nov;85:102727. doi: 10.1016/j.drugpo.2020.102727..
Keywords: Rural Health, Opioids, Substance Abuse, Medication, Hepatitis, Risk, Behavioral Health
Mills J, Wonoprabowo L
AHRQ Author: Mills J
Primary care-based interventions to prevent illicit drug use in children, adolescents, and young adults.
This case study concerns a 14-year-old patient who presents for a well-child visit. The patient eats a healthy diet, is part of a local soccer league, is an overall good student, and just started high school in the fall. The patient denies trying any illicit substances but reports trying to “get high” from cough syrup. Three questions are presented, and answers provided.
AHRQ-authored.
Citation: Mills J, Wonoprabowo L .
Primary care-based interventions to prevent illicit drug use in children, adolescents, and young adults.
Am Fam Physician 2020 Oct 15;102(8):493-94..
Keywords: Children/Adolescents, Young Adults, Substance Abuse, Primary Care, Prevention, U.S. Preventive Services Task Force (USPSTF), Case Study, Guidelines, Evidence-Based Practice
Thompson HM, Faig W, VanKim NA HM, Faig W, VanKim NA
Differences in length of stay and discharge destination among patients with substance use disorders: The effect of Substance Use Intervention Team (SUIT) consultation service.
Addiction medicine consultation services (ACS) may improve outcomes of hospitalized patients with substance use disorders (SUD). The aim of the study was to examine the difference in length of stay and the hazard ratio for a routine hospital discharge between SUD patients receiving and not receiving ACS. The authors concluded that the Substance Use Intervention Team (SUIT) consultation service was associated with a reduced length of stay and an increased hazard of a routine discharge.
AHRQ-funded; HS026385.
Citation: Thompson HM, Faig W, VanKim NA HM, Faig W, VanKim NA .
Differences in length of stay and discharge destination among patients with substance use disorders: The effect of Substance Use Intervention Team (SUIT) consultation service.
PLoS One 2020 Oct 9;15(10):e0239761. doi: 10.1371/journal.pone.0239761..
Keywords: Substance Abuse, Hospitalization, Inpatient Care, Hospital Discharge, Hospitals
Steele DW, Becker SJ, Danko KJ
Brief behavioral interventions for substance use in adolescents: a meta-analysis.
Adolescents with problematic substance use (SU) are at risk for far-reaching adverse outcomes. The objective of this study was to synthesize the evidence regarding the effects of brief behavioral interventions for adolescents (12-20 years) with problematic SU. The investigators concluded that the use of a behavioral intervention called motivational interviewing reduced heavy alcohol use, alcohol use days, and SU-related problems in adolescents but did not reduce cannabis use days.
AHRQ-funded; 290201500002I.
Citation: Steele DW, Becker SJ, Danko KJ .
Brief behavioral interventions for substance use in adolescents: a meta-analysis.
Pediatrics 2020 Oct;146(4):e2020351. doi: 10.1542/peds.2020-0351..
Keywords: Children/Adolescents, Substance Abuse, Alcohol Use, Treatments
Alley L, Novak K, Havlin T
Development and pilot of a prescription drug monitoring program and communication intervention for pharmacists
The authors developed the Resources Encouraging Safe Prescription Opioid and Naloxone Dispensing (RESPOND) Toolkit to enhance community pharmacists' understanding of their role in addressing opioid safety; to improve integration of prescription drug monitoring program (PDMP) into daily workflow; and to enhance communication between pharmacists, prescribers, and patients. In this paper, they described the development of the RESPOND Toolkit and summarized their findings from initial pilot testing. They concluded that the RESPOND Toolkit has promise as an effective and scalable approach to providing community pharmacist-tailored training to promote behavioral shifts supporting opioid safety for patients.
AHRQ-funded; HS024227.
Citation: Alley L, Novak K, Havlin T .
Development and pilot of a prescription drug monitoring program and communication intervention for pharmacists
Res Social Adm Pharm 2020 Oct;16(10):1422-30. doi: 10.1016/j.sapharm.2019.12.023..
Keywords: Opioids, Substance Abuse, Medication, Medication: Safety, Patient Safety, Tools & Toolkits, Communication, Provider: Pharmacist, Provider, Training
Donovan E, Bratberg J, Baird J
Pharmacy leaders' beliefs about how pharmacies can support a sustainable approach to providing naloxone to the community.
The objective of this qualitative study was to understand how leaders in pharmacy organizations perceive pharmacies and pharmacy staff can optimize dispensing of naloxone. Five main themes emerged: importance of staff training to increase comfort; strength through coordination of efforts; pharmacies acting as community leaders in the opioid crisis; persisting stigma; ongoing workflow challenges. These results uniquely reflect the experiences and insights of pharmacy leaders implementing public health initiatives during the opioid crisis and can be used for gaining insight into how pharmacists can efficiently provide naloxone to their communities.
AHRQ-funded; HS024021.
Citation: Donovan E, Bratberg J, Baird J .
Pharmacy leaders' beliefs about how pharmacies can support a sustainable approach to providing naloxone to the community.
Res Social Adm Pharm 2020 Oct;16(10):1493-97. doi: 10.1016/j.sapharm.2020.01.006..
Keywords: Provider: Pharmacist, Provider, Community-Based Practice, Opioids, Medication, Substance Abuse
Zittleman L, Curcija K, Sutter C
Building capacity for medication assisted treatment in rural primary care Practices: the IT MATTTRs practice team training.
In response to rural communities and practice concerns related to opioid use disorder (OUD), the Implementing Technology and Medication Assisted Treatment Team Training in Rural Colorado study (IT MATTTRs) developed a training intervention for full primary care practice (PCP) teams in MAT for OUD. This evaluation reports on training implementation, participant satisfaction, and impact on perceived ability to deliver MAT.
AHRQ-funded; HS025065.
Citation: Zittleman L, Curcija K, Sutter C .
Building capacity for medication assisted treatment in rural primary care Practices: the IT MATTTRs practice team training.
J Prim Care Community Health 2020 Jan-Dec;11:2150132720953723. doi: 10.1177/2150132720953723..
Keywords: Medication, Primary Care, Opioids, Substance Abuse, Rural Health, Training, Education: Continuing Medical Education
Eaton EF, Lee RA, Westfall AO
An integrated hospital protocol for persons with injection-related infections may increase medications for opioid use disorder use but challenges remain.
This study looked at whether a hospital-based protocol would increase the use of medications for opioid use disorder (MOUD) for persons who are hospitalized for infectious complications. Participants who received care for an infection at the University of Alabama at Birmingham Hospital from 2015 to 2018 were included. The protocol included use of an intravenous antibiotic and addiction team (IVAT) consultation and a 9-item risk assessment. The percentage of patients with OUD receiving MOUD increased significantly with IVAT (29% to 37%) and MOUD use was higher in “high risk” participants (62%). However, the uptake of MOUD remains suboptimal at less than 50%.
AHRQ-funded; HS023009.
Citation: Eaton EF, Lee RA, Westfall AO .
An integrated hospital protocol for persons with injection-related infections may increase medications for opioid use disorder use but challenges remain.
J Infect Dis 2020 Sep 2;222(Suppl 5):S499-s505. doi: 10.1093/infdis/jiaa005..
Keywords: Opioids, Substance Abuse, Medication, Infectious Diseases, Hospitals
McClellan C, Maclean JC, Saloner B
AHRQ Author: McClellan C
Integrated care models and behavioral health care utilization: quasi-experimental evidence from Medicaid health homes.
This study provided the first population-level evidence on the effects of Medicaid health homes (HH) on behavioral health care service use. As of 2016, 16 states had adopted an HH for enrollees with serious mental illness and/or substance use disorder. Using data from the National Survey on Drug Use and Health, the authors found that HH adoption increased service use among enrollees and enrollee self-reported health improved post-HH.
AHRQ-authored.
Citation: McClellan C, Maclean JC, Saloner B .
Integrated care models and behavioral health care utilization: quasi-experimental evidence from Medicaid health homes.
Health Econ 2020 Sep;29(9):1086-97. doi: 10.1002/hec.4027..
Keywords: Behavioral Health, Medicaid, Substance Abuse, Primary Care: Models of Care, Primary Care, Ambulatory Care and Surgery, Patient-Centered Outcomes Research
Eaton EF, Vettese T
Management of opioid use disorder and infectious disease in the inpatient setting.
Interactions between patients with acute bacterial infections and acute care physicians provide an opportunity to diagnose opioid use disorder (OUD) and treat patients with medications for OUD. This paper discusses Addiction Medicine Consultation and, when this resource is unavailable, employing infectious diseases providers, hospitalists, and other clinicians to serve a valuable role in the diagnosis and treatment of OUD.
AHRQ-funded; HS023009.
Citation: Eaton EF, Vettese T .
Management of opioid use disorder and infectious disease in the inpatient setting.
Infect Dis Clin North Am 2020 Sep;34(3):511-24. doi: 10.1016/j.idc.2020.06.008..
Keywords: Opioids, Medication, Substance Abuse, Infectious Diseases, Inpatient Care
Green TC, Donovan E, Klug B
Revisiting pharmacy-based naloxone with pharmacists and naloxone consumers in 2 states: 2017 perspectives and evolving approaches.
The authors sought to examine similarities and differences in experiences obtaining naloxone at the pharmacy over a 1-year period in 2 states, and to explore reactions from people with opioid use disorder, patients taking opioids for chronic pain, caregivers of opioid users, and pharmacists to communication tools and patient outreach materials designed to improve naloxone uptake. Through focus groups in Massachusetts and Rhode Island, they found that experiences dispensing naloxone are quickly evolving, and a greater diversity of patients are obtaining pharmacy naloxone. They concluded that persistent stigma-related concerns underscore the need for tools to help pharmacists offer naloxone, facilitate patient requests, and provide reassurance when getting naloxone.
AHRQ-funded; HS024021.
Citation: Green TC, Donovan E, Klug B .
Revisiting pharmacy-based naloxone with pharmacists and naloxone consumers in 2 states: 2017 perspectives and evolving approaches.
J Am Pharm Assoc (2003) 2020 Sep-Oct;60(5):740-49. doi: 10.1016/j.japh.2020.03.005..
Keywords: Opioids, Medication, Substance Abuse, Community-Based Practice, Healthcare Delivery, Social Stigma, Access to Care
Shoemaker-Hunt SJ, Wyant BE
The effect of opioid stewardship interventions on key outcomes: a systematic review.
In this study, the investigators sought to identify potential patient safety practices to reduce high-risk opioid prescribing. They conducted a systematic review of the literature to identify opioid stewardship (OS) strategies implemented in primary care and other settings. The investigators concluded that the strength of the evidence was low to moderate that OS efforts decreased numbers of opioid prescriptions, proportion of patients on long-term opioids, or days' supply. The strength of the evidence for OS initiatives producing significant reductions in opioid dosages was moderate.
AHRQ-funded; 233201500013I.
Citation: Shoemaker-Hunt SJ, Wyant BE .
The effect of opioid stewardship interventions on key outcomes: a systematic review.
J Patient Saf 2020 Sep;16(3S Suppl 1):S36-s41. doi: 10.1097/pts.0000000000000710..
Keywords: Opioids, Medication, Medication: Safety, Patient Safety, Evidence-Based Practice, Patient-Centered Outcomes Research, Substance Abuse, Prevention
Fan T, Smith HJ
AHRQ Author: Fan T
Primary care interventions for prevention and cessation of tobacco use in children and adolescents.
In this case study, three questions are posed concerning a 13-year-old girl presenting for a routine well-child visit who reports that she has never used tobacco products in any form.
AHRQ-authored.
Citation: Fan T, Smith HJ .
Primary care interventions for prevention and cessation of tobacco use in children and adolescents.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Case Study, Children/Adolescents, Tobacco Use: Smoking Cessation, Tobacco Use, Primary Care, Prevention, Substance Abuse
Kim JH, Fine DR, Li L
Disparities in United States hospitalizations for serious infections in patients with and without opioid use disorder: a nationwide observational study.
This study examined the differences in patients with and without opioid use disorder (OUD) who were hospitalized for serious infections focusing on infective endocarditis, epidural abscess, septic arthritis or osteomyelitis. The authors used the 2016 National Inpatient Sample to examine differences in length of stay (LOS), discharge disposition, and charges. Patients with OUD had a lower probability of discharge at any given LOS, and lower odds of discharge to home with higher odds of discharge to a post-acute care facility. There were no significant differences in average total hospital charges.
AHRQ-funded; HS026215.
Citation: Kim JH, Fine DR, Li L .
Disparities in United States hospitalizations for serious infections in patients with and without opioid use disorder: a nationwide observational study.
PLoS Med 2020 Aug;17(8):e1003247. doi: 10.1371/ournal.pmed.1003247.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Disparities, Opioids, Substance Abuse, Hospitalization, Medication, Infectious Diseases
Wisk LE, Magane KM, Levy S
Alcohol use behaviors and reasons to abstain from or limit drinking among medically vulnerable youth.
Youth with chronic medical conditions (YCMC) use alcohol at levels similar to their healthy peers but face elevated risk for adverse health consequences. As salient reasons to abstain from or limit drinking (RALD) among YCMC are unknown, the investigators sought to identify clusters of RALD and test associations with use behaviors. The investigators concluded that for YCMC, RALD were complex but endorsement of multiple general and health-related RALD was associated with less use, and health concerns are especially prevalent.
AHRQ-funded; HS022986.
Citation: Wisk LE, Magane KM, Levy S .
Alcohol use behaviors and reasons to abstain from or limit drinking among medically vulnerable youth.
J Addict Med 2020 Jul/Aug;14(4):311-18. doi: 10.1097/adm.0000000000000603..
Keywords: Children/Adolescents, Alcohol Use, Behavioral Health, Vulnerable Populations, Substance Abuse
Rowell-Cunsolo TL, Liu J, Hu G
Length of hospitalization and hospital readmissions among patients with substance use disorders in New York City, NY USA.
In the United States, the number of patients with substance use disorders is steadily increasing. Individuals with a substance use disorder may be more likely to experience negative hospital outcomes, including lengthier hospital stays and frequent readmissions, which is extremely costly to patients and to the government. In this study, the investigators assessed whether hospital admissions diagnosed with substance use disorders experienced longer hospital stays and readmissions compared to patients without a substance use disorder diagnosis.
AHRQ-funded; HS024915.
Citation: Rowell-Cunsolo TL, Liu J, Hu G .
Length of hospitalization and hospital readmissions among patients with substance use disorders in New York City, NY USA.
Drug Alcohol Depend 2020 Jul 1;212:107987. doi: 10.1016/j.drugalcdep.2020.107987..
Keywords: Substance Abuse, Hospitalization, Hospital Readmissions
McClellan C, Flottemesch TJ, Ali MM
AHRQ Author: McClellan C
Physician networks and potentially inappropriate opioid prescriptions.
The authors examined associations between care networks defined by shared patients and problematic opioid prescribing using four behaviors defined by the CDC guidelines. They found that greater provider integration was associated with a lower risk of a provider's patients repeatedly having potentially inappropriate prescription fills; however, the association with a provider having any potentially problematic prescription was more ambiguous.
AHRQ-authored.
Citation: McClellan C, Flottemesch TJ, Ali MM .
Physician networks and potentially inappropriate opioid prescriptions.
J Addict Dis 2020 Jul-Sep;38(3):301-10. doi: 10.1080/10550887.2020.1760655..
Keywords: Opioids, Medication, Medication: Safety, Substance Abuse, Patient Safety, Provider
Patnode CD, Perdue LA, Rushkin M
Screening for unhealthy drug use: updated evidence report and systematic review for the US Preventive Services Task Force.
Illicit drug use is among the most common causes of preventable morbidity and mortality in the US. The objective of this study was to conduct a systematic review of the literature on screening and interventions for drug use to inform the US Preventive Services Task Force. The investigators concluded that several screening instruments with acceptable sensitivity and specificity are available to screen for drug use, although there is no direct evidence on the benefits or harms of screening.
AHRQ-funded; 290201500007I.
Citation: Patnode CD, Perdue LA, Rushkin M .
Screening for unhealthy drug use: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2020 Jun 9;323(22):2310-28. doi: 10.1001/jama.2019.21381..
Keywords: U.S. Preventive Services Task Force (USPSTF), Substance Abuse, Screening, Evidence-Based Practice, Guidelines, Primary Care, Prevention
Burner E, Zhang M, Terp S
Feasibility and acceptability of a text message-based intervention to reduce overuse of alcohol in emergency department patients: controlled proof-of-concept trial.
The objective of this study was to assess the feasibility of and patient satisfaction with a text-based mHealth extension of an emergency department (ED) screening program to reduce risky alcohol use in low-income, urban patients. A case-control study was designed using a SMS text message-capable phones to receive mROAD (mobilizing to Reduce Overuse of Alcohol in the ED), an SMS text message-based extension of the ED screening program. mROAD is a 7-day program of twice-daily SMS text messages based on the NIH Health Rethinking Drinking campaign. Of 1028 patients screened, 9.2% exhibited risky alcohol use based on the Alcohol Use Disorders Identification Test (AUDIT) in the ED. Almost a quarter of the patients did not have an SMS text-messaging capable phone, leaving 76% eligible patients. Changes in behavior were similar between the two groups. The number of drinking days reported in the prior 30 days decreased by 5 and the number of heavy drinking days decreased by 4.1. Patients reported an 11-point increase in motivation to change alcohol use via the Change Questionnaire.
AHRQ-funded; HS022402.
Citation: Burner E, Zhang M, Terp S .
Feasibility and acceptability of a text message-based intervention to reduce overuse of alcohol in emergency department patients: controlled proof-of-concept trial.
JMIR Mhealth Uhealth 2020 Jun 4;8(6):e17557. doi: 10.2196/17557..
Keywords: Alcohol Use, Substance Abuse, Emergency Department, Telehealth, Health Information Technology (HIT), Screening, Prevention
Friedman AS, Xu S
Associations of flavored e-cigarette uptake with subsequent smoking initiation and cessation.
Researchers evaluated whether new uptake of flavored e-cigarettes is more strongly associated with subsequent smoking initiation and cessation than uptake of unflavored e-cigarettes for youths, emerging adults, and prime-age adults. The cohort study conducted secondary data analyses of survey data from the Population Assessment of Tobacco and Health Study. The researchers found that vaping uptake was positively associated with smoking initiation in youth and in emerging adults, while vaping uptake was associated with cessation in adults. Additionally, vaping nontobacco flavors was no more associated with youth smoking initiation than vaping tobacco-flavors but was associated with increased adult smoking cessation. They recommended more research to establish the relationship between e-cigarette flavors and smoking and to guide related policy.
AHRQ-funded; HS017589.
Citation: Friedman AS, Xu S .
Associations of flavored e-cigarette uptake with subsequent smoking initiation and cessation.
JAMA Netw Open 2020 Jun;3(6):e203826. doi: 10.1001/jamanetworkopen.2020.3826..
Keywords: Children/Adolescents, Young Adults, Tobacco Use: Smoking Cessation, Tobacco Use, Substance Abuse