The November 1999 report of the Institute of Medicine (IOM), To Err is Human: Building a Safer System, focused attention on the unacceptable number of medical errors occurring in the United States every day. The report brought patient safety to the forefront of our attention and led to unprecedented efforts to find solutions. The report showed that a wide gap exists in the quality of care people receive and the quality of care that we as a Nation are capable of providing. According to the IOM, as many as 44,000 to 98,000 people die in hospitals each year as a result of medical errors. Even using the lower estimate, this would make medical errors the eighth leading cause of death in this country.
Medical errors cause more deaths annually than automobile accidents (43,458), breast cancer (42,297), or AIDS (16,516). An estimated 7,000 people die each year from medication errors alone, about 16 percent more deaths than the number attributable to work-related injuries. Moreover, while errors may be more easily detected in hospitals, they affect every health care setting: day-surgery and outpatient clinics, retail pharmacies, nursing homes, and home care.
Research on medical errors and other patient safety issues is not new to AHRQ. We have recognized for some time that reducing medical errors is critically important for improving the quality of health care. In 1993, the agency published one of the first reports focused on medical errors. This landmark report noted that 78 percent of adverse drug reactions were due to system failures, such as the misreading of handwritten prescriptions. Subsequent studies sponsored by AHRQ have focused on the detection of medical errors, investigation of diagnostic inaccuracies, the relationship between nurse staffing and adverse events, computerized monitoring of adverse drug events, and tools for computer-assisted decisionmaking that can reduce the potential for errors and improve safety.
The IOM's 1999 report also called for the establishment of patient safety reporting systems, including State-based systems for accountability purposes that focus on serious adverse events and no-harm events (near misses). The IOM report also recommended that steps be taken to develop data standards to maximize the usefulness of the data collected, minimize the reporting burden, and allow for comparisons across reporting systems and over time.
To encourage the growth of voluntary, confidential reporting systems so that practitioners and health care organizations can correct problems before serious harm occurs, the report recommends Federal legislation to protect the confidentiality of certain information. Hospitals first, and eventually other places where patients get care, would be responsible for reporting such events to State governments. Currently, about one-third of the States have their own mandatory reporting requirements.
AHRQ has made considerable progress in the area of providing guidance to facilitate State reporting efforts. These efforts include analyses of State-based patient safety reporting systems conducted by the National Academy for State Health Policy and through the work of the HHS Patient Safety Task Force (PSTF). The PSTF consists of AHRQ, the Centers for Disease Control and Prevention, the Food and Drug Administration, and the Centers for Medicare & Medicaid Services. The Task Force's efforts are focused on how to improve adverse event reporting through the systems these agencies presently operate to better coordinate research and analysis efforts and promote collaboration on reducing the occurrence of injuries that result from medical errors.
In carrying out these and other activities, AHRQ identified the need for additional guidance on the standardization and coding of data submitted to patient safety reporting systems. To further advance our knowledge in this area, IOM published a report in November 2003, requested and funded by AHRQ, that provides input on how patient safety can be improved through the establishment of a national health information infrastructure and health care standards. This report also provides input that will assist with other ongoing patient safety improvement programs, including HHS work on a consolidated patient safety database and AHRQ's current patient safety research aimed at identifying how to improve safety and move those findings into practice.
Between FY 2001 and 2003, AHRQ invested $160 million in research grants, contracts, and other projects to reduce medical errors and improve patient safety. This effort represents the Federal Government's largest single investment in research on medical errors. These projects fall into four broad categories:
The results of this research will identify improvement strategies that work in hospitals, doctors' offices, nursing homes, and other health care settings across the Nation. Also, as mentioned earlier, the work of the HHS Patient Safety Task Force will help in strengthening the reporting, analysis, and sharing of information on adverse patient safety events.
The results of AHRQ's substantial investment in a multi-year effort to reduce medical errors, enhance patient safety, improve quality in all areas of health care, and inform patients about how they can influence the quality of care they receive, are now being incorporated into practice. For example, AHRQ's Center for Education and Research on Therapeutics (CERT) at the University of Arizona Health Science Center developed a unique educational and research tool that contains a list of 72 drugs that can cause life-threatening heart arrhythmia (abnormal heartbeat).
Caregivers around the globe can go to this online resource at www.qtdrugs.org to research specific drugs that might pose a risk to their patients as well as to submit clinical cases of drug-induced arrhythmias to the registry. Researchers are using the information submitted to develop profiles of people most at risk for drug-induced arrhythmias and to develop a genetic test that can identify them in advance of treatment.
In FY 2003, AHRQ continued its research to raise the level of patient safety in U.S. health care. Examples of new AHRQ-supported projects in this area:
Journal Features AHRQ-Supported Research on Health Care QualityFour articles, stemming from AHRQ-supported research, about different aspects of health care quality were featured in the March/April 2003 issue of Health Affairs—a peer-reviewed journal that explores health policy issues of current concern in both domestic and international spheres. Topics examined in the articles:
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Quality health care means doing the right thing, at the right time, in the right way, for the right person, and ultimately, achieving the best possible results. The United States has many of the world's finest health care professionals, academic health care centers, and other institutions. Every day, millions of Americans receive high-quality health care services that help to maintain or restore their health and ability to function. However, far too many do not, and some patients receive substandard care.
Quality problems may be reflected in a wide variation in the use of health care services, underuse of some services, overuse of other services, and even misuse of services, including an unacceptable level of errors. Sometimes patients receive more services than they need or they receive unnecessary services that undermine the quality of their care and needlessly increase costs. At other times they do not receive needed services that have been proven to be effective.
For example, nationwide only about 40 percent of the 31 million Americans with diagnosed high blood pressure have their blood pressure adequately controlled. An increase to 68 percent—the level already achieved by the Nation's top health plans—would save an estimated 28,000 lives per year. The loss of life is compounded by the financial costs the Nation pays for these unnecessary gaps in care. Hospitalizations due to avoidable second heart attacks cost the American economy more than $1.6 billion a year.
The research that provided much of the basis for the 2001 report by the Institute of Medicine (IOM), Crossing the Quality Chasm, goes back several decades to early studies on quality of care, most of which were supported by AHRQ and its predecessor agencies. In its report, the IOM pointed out that quality problems occur across all types of cancer care and in all aspects of the process of care. For instance, the IOM report described "underuse of mammography for early cancer detection, lack of adherence to standards for diagnosis, inadequate patient counseling regarding treatment options, and underuse of radiation therapy and adjuvant chemotherapy following surgery."
Poor quality care results in patients who are sicker, have more disabilities, incur higher costs, and have lower confidence in the Nation's health care system. The National Committee for Quality Assurances' State of Health Care Quality Report: 2003 finds that the health care system's failure to treat just five health care conditions— asthma, depression, diabetes, heart disease, and high blood pressure—with the best available care is responsible for nearly 41 million sick days. This translates to the equivalent productivity of more than 173,000 workers and annual costs to American companies of more than $11.5 billion.
There is great potential to improve the quality of health care provided to Americans, and AHRQ is committed to this goal. We are working to maintain what is good about the existing health care system while paying special attention to the areas that need improvement. Improving the quality of care and reducing medical errors are priority areas for the Agency. AHRQ is working to develop and test measures of quality; identify the best ways to collect, compare, and communicate data on quality; and widely disseminate information about effective strategies to improve the quality of care.
Findings from recent AHRQ-supported research on health care quality:
Examples of AHRQ-supported research projects now in progress that focus on improving health care quality:
As part of AHRQ's commitment to enhancing the quality of health care for all Americans, the Agency has played a major role in developing, refining, and disseminating quality measures and related resources. These research-based tools serve two purposes. First, they provide consumers with the reliable, evidence-based information they need to choose wisely among health plans, practitioners, and facilities and get the health care that is best for them. Second, they offer providers the validated, comparative data they need to assess strengths and weaknesses in their performance.
In particular, AHRQ has been the driving force behind a set of measures and tools that focus on patients' experiences with health care and services. Under the CAHPS® program, the Agency is funding a public-private team of researchers to develop a comprehensive and evolving family of surveys that ask consumers and patients to evaluate the interpersonal aspects of health care. CAHPS® surveys probe those aspects of care for which consumers and patients are the best and/or only source of information, as well as those that consumers and patients have identified as being important.
The acronym CAHPS® initially stood for the Consumer Assessment of Health Plans Study. However, in the current CAHPS® program—known as CAHPS® II—the products have evolved beyond health plans, so the acronym now stands alone as a registered brand name.
In FY 2003, the results of the widely adopted CAHPS® Health Plan Survey were available to help more than 123 million Americans with their health care benefits decisions. Building on the success of the Health Care Survey, the Agency and the CAHPS® research team (known as the Consortium) began work on "Ambulatory CAHPS®," or A-CAHPS. The goal of this new initiative is to develop an integrated suite of survey instruments that will provide consumers and providers with information on patients' experiences with medical groups, individual clinicians, sites of care, and health plans.
In conceiving the A-CAHPS initiative, AHRQ and the CAHPS® Consortium relied heavily on extensive market research with both users and non-users of CAHPS® products to identify and clarify their information needs. To ensure that the research-based products that arise from this initiative truly do meet the needs of those who will put them into practice, AHRQ also embarked on a long-term process of building bridges with a variety of stakeholders, including associations that represent medical groups, health plans, and individual clinicians.
To expand on the usefulness of CAHPS® products, CAHPS® II calls for an exploration of new uses for information on quality of care from the patients' perspective. Consequently, AHRQ and its partners have been evaluating the usefulness of survey-based information as a quality improvement tool for health care organizations, which can use the standardized data to identify relative strengths and weaknesses in their performance and determine what aspects of interpersonal care they need to improve.
To support this new emphasis, the Agency and members of the CAHPS® team initiated two collaborations with the health care industry:
The results of these projects will be incorporated into the A-CAHPS® initiative.
In addition to finding ways to make CAHPS® surveys more useful in the quality improvement arena, CAHPS® II focuses on assessing the experiences of special populations (such as American Indians) and refining techniques for reporting survey findings and other quality information to consumers. In FY 2003, AHRQ and the CAHPS® Consortium conducted substantial research to identify effective reporting strategies and the challenges posed by different subgroups in the population.
CAHPS® II also includes a requirement for the development, testing, and distribution of effective tools for assessing patients' experiences with levels of the health care system beyond health plans. One example of this work is the ECHO Survey, which assesses patients' perspectives on behavioral health services. This survey was submitted and accepted as a formal CAHPS® survey in FY 2003. In addition, FY 2003 saw significant progress in the development of several other CAHPS® products, all of which benefitted from collaborations with a variety of public and private organizations.
Working closely with CMS and its partners in the Consortium, AHRQ made substantial strides with Hospital CAHPS® (HCAHPS®) in FY 2003. Specifically, we gathered and assessed existing inpatient surveys, developed a draft survey, conducted cognitive testing with consumers, sought input from various stakeholder groups (including hospitals, data collection vendors, and others), elicited feedback from consumers, received and responded to extensive public comments, and initiated a field test of the draft instrument in three States.
AHRQ and its partners also worked with CMS to develop and test displays of the survey results, which will be published on CMS's public "Medicare Compare" Web site.
One of AHRQ's most important priorities is translating research into practice. We are constantly working to make sure research findings are put to work to help patients and consumers get the best possible health care. AHRQ and its partners continue to develop and disseminate many products to help patients choose wisely when it comes to their health care.
Projects undertaken in FY 2003 that focus on providing health care quality information that will be useful to patients and consumers:
AHRQ, the Centers for Medicare & Medicaid Services, the Office of Personnel Management, and the Department of Labor created posters and fact sheets called 5 Steps to Safer Health Care, which offer evidence-based practical tips on the role that patients can play to help improve the safety of the care they receive. The tips address errors related to prescription medicines, laboratory tests, procedures, and surgery.
AHRQ launched the new Web-based National Quality Measures Clearinghouse™ (NQMC™) in FY 2003. Currently, the NQMC™ contains more than 300 quality measures. It presents the most current evidence-based quality measures and measure sets available to evaluate and improve the quality of health care.
The site is designed to be a "one-stop shop" for physicians, hospitals, health plans, and others who may be interested in quality measures. Users can search the NQMC™ for measures that target a particular disease/condition, treatment/intervention, age range, sex, vulnerable population, or setting of care. Additionally, users may browse NQMC™ by organization or measure domain. Visitors can compare attributes of two or more quality measures side by side to determine which measures best suit their needs. The site also provides material on how to select, use, apply, and interpret a measure.
In order to be included in the NQMC™, measures must satisfy the inclusion criteria. The NQMC™ inclusion criteria are available at: http://www.qualitymeasures.ahrq.gov/about/inclusion.aspx.
A brief description of the criteria:
Measures can be submitted to NQMC™ on an ongoing basis. Measures are submitted by national, State, and local organizations involved in developing and/or using quality measurement tools. These include health care systems, accreditation organizations, professional associations, research institutions, licensing boards, and other relevant organizations.
The NQMC™ builds on AHRQ's previous initiatives in quality measurement and is linked to an umbrella quality improvement clearinghouse, Quality Tools, which can be found at http://www.qualitytools.ahrq.gov. This new, expanded site comprises over 140 quality, clinical information, and decision tool components for patients, consumers, providers, purchasers, payers and policymakers. QualityTools enables these audiences to find tools to meet their specific needs.
Examples of tools contained in the clearinghouse:
QualityTools also features the National Healthcare Quality Report and the National Healthcare Disparities Report and is linked to the National Guideline Clearinghouse™ (NGC), providing users ready access to evidence-based clinical practice guidelines. The NQMC™ and NGC linkage allows users to coordinate their search for quality measures with the original supporting guideline recommendations.