Appendix Table 2. Data Used in the Analysis

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Appendix Table 2. Data Used in the Analysis^a

Study: CNBSS

Ref	Age	Mean FU	Intervention Group: Deaths	Intervention Group: Subjects	Intervention Group: Life-years	Intervention Group: Rate/10,000	Control Group: Deaths	Control Group: Subjects	Control Group: Life-years	Control Group: Rate/10,000	95% CI: RR	95% CI: Lower	95% CI: Upper
Miller, unpublished manuscript	40-49	13.0	105	25,214	282,606	3.7	108	25,216	282,575	3.8	0.97	0.74	1.27
Miller et al, 1997^21,b	40-49	10.5	82	25,214	264,747	3.1	72	25,216	264,768	2.7	1.14	0.83	1.56
Miller et al, 1992¹²	40-49	8.5	38	25,214	214,319	1.8	28	25,216	214,336	1.3	1.36	0.84	2.21
	40-59	13.0	212	44,925	584,025	3.6	213	44,910	583,830	3.6	1.00	0.82	1.20
	40-59	8.5	76	44,925	381,863	2.0	67	44,910	381,735	1.8	1.13	0.82	1.57
Miller et al, 2000²⁰	50-59	13.0	107	19,711	216,133	5.0	105	19,694	216,042	4.9	1.02	0.78	1.33
Miller et al, 1992¹³	50-59	8.3	38	19,711	163,601	2.3	39	19,694	163,460	2.4	0.97	0.62	1.52

Study: HIP

Ref	Age	Mean FU	Intervention Group: Deaths	Intervention Group: Subjects	Intervention Group: Life-years	Intervention Group: Rate/10,000	Control Group: Deaths	Control Group: Subjects	Control Group: Life-years	Control Group: Rate/10,000	95% CI: RR	95% CI: Lower	95% CI: Upper
Shapiro, 1997^27,b	40-49	18.0	49	13,740	247,320	2.0	65	13,740	247,320	2.6	0.75	0.52	1.09
Habbema et al, 1986¹²²	40-49	14.0	64	13,740	192,360	3.3	82	13,740	192,360	4.3	0.78	0.56	1.08
Shapiro et al, 1988¹⁹	40-49	10.0	39	13,740	137,400	2.8	51	13,740	137,400	3.7	0.76	0.50	1.16
Shapiro et al, 1988¹⁹	40-49	5.0	19	13,740	68,700	2.8	20	13,740	68,700	2.9	0.95	0.51	1.78
Shapiro et al, 1988¹⁹	40-64	18.0	126	30,245	544,410	2.3	163	30,245	544,410	3.0	0.77	0.61	0.98
Shapiro et al, 1985¹²³	40-64	16.0	236	30,239	483,824	4.9	281	30,756	492,096	5.7	0.85	0.72	1.02
Habbema et al, 1986¹²²	40-64	14.0	165	30,245	423,430	3.9	212	30,245	423,430	5.0	0.78	0.64	0.95
Shapiro et al, 1988¹⁹	40-64	10.0	95	30,245	302,450	3.1	133	30,245	302,450	4.4	0.71	0.55	0.93
Shapiro et al, 1988¹⁹	40-64	5.0	39	30,245	151,225	2.6	63	30,245	151,225	4.2	0.62	0.42	0.92
Shapiro et al, 1988¹⁹	50-64	18.0	77	16,505	297,090	2.6	98	16,505	297,090	3.3	0.79	0.58	1.06
Habbema et al, 1986¹²²	50-64	14.0	101	16,505	231,070	4.4	130	16,505	231,070	5.6	0.78	0.60	1.01
Shapiro et al, 1988¹⁹	50-64	10.0	56	16,505	165,050	3.4	82	16,505	165,050	5.0	0.68	0.49	0.96
Shapiro et al, 1988¹⁹	50-64	5.0	20	16,505	82,525	2.4	43	16,505	82,525	5.2	0.47	0.27	0.79

Study: Gothenburg

Ref	Age	Mean FU	Intervention Group: Deaths	Intervention Group: Subjects	Intervention Group: Life-years	Intervention Group: Rate/10,000	Control Group: Deaths	Control Group: Subjects	Control Group: Life-years	Control Group: Rate/10,000	95% CI: RR	95% CI: Lower	95% CI: Upper
Bjurstam et al, 1997^24,b	39-49	11.8	18	11,724	138,402	1.3	40	14,217	168,025	2.4	0.55	0.31	0.96
Nystrom et al, 2002²³	40-49	12.7	22	10,888	138,000	1.6	46	13,203	167,000	2.8	0.58	0.35	0.96
Larsson et al, 1997⁵⁰	40-49	9.8	16	10,821	106,000	1.5	33	13,101	129,000	2.6	0.59	0.33	1.06
Nystrom et al, 2002²³	40-59	12.8	62	21,000	268,000	2.3	113	29,200	373,000	3.0	0.76	0.56	1.04
Nystrom et al, 1993³²	40-59	6.3	27	20,724	129,000	2.1	47	28,809	181,000	2.6	0.86	0.54	1.37
Nystrom et al, 2002²³	50-59	12.9	40	10,112	130,000	3.1	67	15,997	206,000	3.3	0.94	0.62	1.43

Study: Stockholm

Ref	Age	Mean FU	Intervention Group: Deaths	Intervention Group: Subjects	Intervention Group: Life-years	Intervention Group: Rate/10,000	Control Group: Deaths	Control Group: Subjects	Control Group: Life-years	Control Group: Rate/10,000	95% CI: RR	95% CI: Lower	95% CI: Upper
Nystrom et al, 2002²³	40-49	14.3	34	14,303	203,000	1.7	13	8,021	117,000	1.1	1.52	0.80	2.88
Frisell and Lidbrink, 1997^124,b	40-49	11.9	24	14,842	173,866	1.4	12	7,103	87,826	1.4	1.08	0.54	2.17
Larsson et al, 1997⁵⁰	40-49	11.5	23	14,185	162,000	1.4	10	7,985	94,000	1.1	1.34	0.64	2.80
Frisell et al, 1991¹²⁵	40-49	7.2	16	14,375	99,155	1.6	8	7,103	54,446	1.5	1.09	0.40	3.00
Frisell et al, 1997¹⁷	40-64	11.8	66	40,318	473,153	1.4	45	19,943	239,460	1.9	0.74	0.50	1.10
Frisell et al, 1991¹²⁵	40-64	7.1	39	39,164	270,247	1.4	30	19,943	147,373	2.0	0.71	0.40	1.20
Nystrom et al, 2002²³	40-65	13.8	82	39,139	535,000	1.5	50	20,978	296,000	1.7	0.91	0.65	1.27
Nystrom et al, 1993³²	40-65	7.6	53	38,525	287,000	1.8	40	20,651	164,000	2.4	0.80	0.53	1.22
Nystrom et al, 2002²³	50-59	13.7	25	15,946	217,000	1.2	24	8,421	118,000	2.0	0.56	0.32	0.97
Frisell et al, 1997¹⁷	50-64	11.8	42	25,476	299,287	1.4	33	12,840	151,634	2.2	0.62	0.38	1.00
Frisell et al, 1991¹²⁵	50-64	7.0	23	24,789	171,092	1.3	22	12,840	92,927	2.4	0.57	0.30	1.10

Study: Malmö I + II

Ref	Age	Mean FU	Intervention Group: Deaths	Intervention Group: Subjects	Intervention Group: Life-years	Intervention Group: Rate/10,000	Control Group: Deaths	Control Group: Subjects	Control Group: Life-years	Control Group: Rate/10,000	95% CI: RR	95% CI: Lower	95% CI: Upper
Nystrom et al, 2002²³	43-49	13.3	53	13,568	184,000	2.9	66	12,279	160,000	4.1	0.73	0.51	1.04
Andersson and Janzon, 1997^15,b	43-49	12.0	57	13,528	165,596	3.4	78	12,242	144,036	5.4	0.64	0.45	0.89
Nystrom et al, 2002²³	43-70	15.3	190	30,669	473,000	4.0	231	29,407	448,000	5.2	0.79	0.65	0.96
Nystrom et al, 2002²³	45-49	18.0	24	3,987	71,000	3.4	33	4,067	74,000	4.5	0.74	0.44	1.25
Larsson et al, 1997⁵⁰	45-49	15.4	15	3,945	61,000	2.5	23	4,017	62,000	3.7	0.67	0.35	1.27
Nystrom et al, 2002²³	45-54	18.2	71	8,673	158,000	4.5	78	8,311	151,000	5.2	0.87	0.63	1.20
Andersson et al, 1988²⁵	45-54	9.0	28	7,981	71,775	3.9	22	8,082	72,635	3.0	1.29	0.74	2.25
Andersson et al, 1988²⁵	45-69	8.8	63	21,088	186,297	3.4	66	21,195	187,016	3.5	0.96	0.68	1.35
Nystrom et al, 2002²³	45-70	17.1	161	21,088	360,000	4.5	198	21,195	362,000	5.5	0.82	0.67	1.00
Nystrom et al, 1993³²	45-70	11.5	87	20,695	239,000	3.6	108	20,783	240,000	4.5	0.81	0.62	1.07
Nystrom et al, 2002²³	50-70	16.9	137	17,101	289,000	4.7	165	17,128	288,000	5.7	0.83	0.66	1.04
Nystrom et al, 2002²³	55-64	17.2	63	8,194	141,000	4.5	83	8,679	149,000	5.6	0.80	0.57	1.12
Andersson et al, 1988²⁵	55-69	8.7	35	13,107	114,522	3.1	44	13,113	114,381	3.8	0.79	0.51	1.24
Nystrom et al, 2002²³	55-70	16.3	90	12,415	202,000	4.5	120	12,884	211,000	5.7	0.78	0.59	1.02

Study: 2-county, Kopparberg

Ref	Age	Mean FU	Intervention Group: Deaths	Intervention Group: Subjects	Intervention Group: Life-years	Intervention Group: Rate/10,000	Control Group: Deaths	Control Group: Subjects	Control Group: Life-years	Control Group: Rate/10,000	95% CI: RR	95% CI: Lower	95% CI: Upper
Tabár et al, 2000²⁶	40-49	17.3	NR	NR	NR	NR	NR	NR	NR	NR	0.76	0.42	1.40
Tabár et al, 1995¹⁶	40-49	13.0	22	9,582	124,566	1.8	16	5,031	65,403	2.4	0.73	0.37	1.41
Tabár et al, 1989²⁸	40-49	7.9	13	9,582	75,698	1.7	9	5,031	39,745	2.3	0.76	0.32	1.77
Tabár et al, 1985³⁵	40-49	6.0	8	9,625	57,750	1.4	3	5,053	30,318	1.0	1.40	0.37	5.28
Tabár et al, 2000²⁶	40-74	17.3	152	NR	672,482	2.3	121	NR	326,091	3.7	0.61	NR	NR
Tabár et al, 1995¹⁶	40-74	13.0	126	38,589	501,657	2.5	104	18,582	241,566	4.3	0.60	0.46	0.79
Tabár et al, 1989²⁸	40-74	7.9	77	38,589	304,853	2.5	58	18,582	146,798	4.0	0.64	0.46	0.90
Tabár et al, 1985³⁵	40-74	6.0	51	39,051	234,306	2.2	39	18,846	113,076	3.4	0.63	0.42	0.96
Tabár et al, 2000²⁶	50-59	17.3	NR	NR	NR	NR	NR	NR	NR	NR	0.46	0.30	0.71
Tabár et al, 1995¹⁶	50-59	13.0	34	11,728	152,464	2.2	34	5,557	72,241	4.7	0.48	0.29	0.77
Tabár et al, 1989²⁸	50-59	7.9	20	9,582	75,698	2.6	20	5,031	39,745	5.0	0.53	0.28	0.98
Tabár et al, 1995¹⁶	50-74	13.0	104	29,007	377,091	2.8	88	13,551	176,163	5.0	0.58	0.43	0.78
Tabár et al, 1989²⁸	50-74	7.9	64	29,007	229,155	2.8	49	13,551	107,053	4.6	0.61	0.42	0.89
Tabár et al, 1985³⁵	50-74	6.0	43	29,426	176,556	2.4	36	13,793	82,758	4.4	0.56	0.36	0.87

Study: 2-county, Östergötland

Ref	Age	Mean FU	Intervention Group: Deaths	Intervention Group: Subjects	Intervention Group: Life-years	Intervention Group: Rate/10,000	Control Group: Deaths	Control Group: Subjects	Control Group: Life-years	Control Group: Rate/10,000	95% CI: RR	95% CI: Lower	95% CI: Upper
Tabár et al, 2000²⁶	40-49	17.3	NR	NR	NR	NR	NR	NR	NR	NR	1.06	0.65	1.76
Nystrom et al, 2002²³	40-49	16.8	31	10,285	172,000	1.8	30	10,459	176,000	1.7	1.05	0.64	1.71
Tabár et al, 1995¹⁶	40-49	13.0	23	10,262	133,406	1.7	23	10,573	137,449	1.7	1.02	0.52	1.99
Tabár et al, 1989²⁸	40-49	7.9	15	10,262	81,070	1.9	15	10,573	83,527	1.8	1.03	0.50	2.11
Tabár et al, 1985³⁵	40-49	6.0	8	10,312	61,872	1.3	7	10,625	63,750	1.1	1.18	0.43	3.25
Tabár et al, 2000²⁶	40-74	17.3	167	NR	660,242	2.5	213	NR	643,696	3.3	0.76	NR	NR
Nystrom et al, 2002²³	40-74	15.2	177	38,942	589,000	3.0	190	37,675	572,000	3.3	0.90	0.73	1.11
Tabár et al, 1995¹⁶	40-74	13.0	135	38,491	500,383	2.7	173	37,403	486,239	3.6	0.78	0.60	1.01
Tabár et al, 1989²⁸	40-74	7.9	83	38,491	304,079	2.7	109	37,403	295,484	3.7	0.74	0.56	0.98
Tabár et al, 1985³⁵	40-74	6.0	36	39,034	234,204	1.5	47	37,936	227,616	2.1	0.74	0.48	1.15
Tabár et al, 2000²⁶	50-59	17.3	NR	NR	NR	NR	NR	NR	NR	NR	0.76	0.53	1.10
Nystrom et al, 2002²³	50-59	16.1	53	12,011	194,000	2.7	54	11,495	185,000	2.9	0.94	0.66	1.35
Tabár et al, 1995¹⁶	50-59	13.0	44	11,757	152,841	2.9	51	11,248	146,224	3.5	0.85	0.52	1.38
Tabár et al, 1989²⁸	50-59	7.9	25	11,757	92,880	2.7	34	11,248	88,859	3.8	0.70	0.42	1.18
Nystrom et al, 2002²³	50-74	14.9	146	28,657	417,000	3.5	160	25,920	396,000	4.0	0.83	0.66	1.03
Tabár et al, 1995¹⁶	50-74	13.0	112	28,229	366,977	3.1	150	26,830	348,790	4.3	0.73	0.56	0.97
Tabár et al, 1989²⁸	50-74	7.9	68	28,229	223,009	3.0	94	26,830	211,957	4.4	0.69	0.50	0.94
Tabár et al, 1985³⁵	50-74	6.0	28	28,722	172,332	1.6	40	27,311	163,866	2.4	0.67	0.41	1.08

Study: Kopparberg + Östergötland

Ref	Age	Mean FU	Intervention Group: Deaths	Intervention Group: Subjects	Intervention Group: Life-years	Intervention Group: Rate/10,000	Control Group: Deaths	Control Group: Subjects	Control Group: Life-years	Control Group: Rate/10,000	95% CI: RR	95% CI: Lower	95% CI: Upper
Tabár et al, 1995¹⁶	40-49	13.0	45	19,844	257,972	1.7	39	15,604	202,852	1.9	0.87	0.54	1.41
Tabár et al, 1989²⁸	40-49	7.9	28	19,844	156,768	1.8	24	15,604	123,272	1.9	0.92	0.52	1.60
Tabár et al, 1989²⁸	40-49	7.9	28	19,844	156,768	1.8	24	15,604	123,272	1.9	0.92	0.53	1.58
Tabár et al, 1985³⁵	40-49	6.0	16	19,937	119,622	1.3	10	15,678	94,068	1.1	1.26	0.56	2.84
Tabár et al, 2000²⁶	40-74	17.3	319	77,080	1,332,724	2.4	334	55,985	969,787	3.4	0.68	0.59	0.80
Tabár et al, 1995¹⁶	40-74	12.5	269	77,080	965,405	2.8	277	55,985	701,207	4.0	0.69	0.57	0.84
Tabár et al, 1989²⁸	40-74	7.9	160	77,080	608,932	2.6	167	55,985	442,282	3.8	0.70	0.56	0.86
Tabár et al, 1985³⁵	40-74	6.0	87	78,085	468,510	1.9	86	56,782	340,692	2.5	0.69	0.51	0.92
Tabár et al, 1995¹⁶	50-59	13.0	78	23,485	305,305	2.6	85	16,805	218,465	3.9	0.66	0.46	0.93
Tabár et al, 1989²⁸	50-59	7.9	45	23,485	185,532	2.4	54	16,805	132,760	4.1	0.60	0.40	0.89
Tabár et al, 1995¹⁶	50-74	13.0	224	57,236	744,068	3.0	238	55,985	727,805	3.3	0.66	0.54	0.81
Tabár et al, 1989²⁸	50-74	7.9	132	57,236	452,164	2.9	143	40,381	319,010	4.5	0.65	0.51	0.83
Tabár et al, 1985³⁵	50-74	6.0	71	58,148	348,888	2.0	76	41,104	246,624	3.1	0.61	0.44	0.84

Study: Edinburgh

Ref	Age	Mean FU	Intervention Group: Deaths	Intervention Group: Subjects	Intervention Group: Life-years	Intervention Group: Rate/10,000	Control Group: Deaths	Control Group: Subjects	Control Group: Life-years	Control Group: Rate/10,000	95% CI: RR	95% CI: Lower	95% CI: Upper
Alexander et al, 1999¹⁸	45-49	12.2	47	11,479	139,868	3.4	53	10,267	126,413	4.2	0.75	0.48	1.18
Alexander, 1997^126,b	45-49	12.2	46	NR	139,871	3.3	52	NR	126,417	4.1	0.88	0.55	1.41
Alexander et al, 1994¹²⁷	45-49	8.5	25	11,505	97,206	2.6	31	10,269	88,766	3.5	0.78	0.46	1.31
Roberts et al, 1990¹²⁸	45-49	6.9	13	5,913	40,851	3.2	13	5,810	40,009	3.2	0.98	NR	NR
Alexander et al, 1999¹⁸	45-64	13.0	156	22,926	301,155	5.2	167	21,342	276,363	6.0	0.79	0.60	1.02
Alexander et al, 1994¹²⁷	45-64	9.5	96	22,944	219,215	4.4	106	21,344	201,821	5.3	0.82	0.61	1.11
Roberts et al, 1990¹²⁸	45-64	6.8	68	23,226	157,946	4.3	76	21,904	147,854	5.1	0.83	0.58	1.18
Alexander et al, 1999¹⁸	50-64	12.9	129	17,149	222,393	5.8	134	15,748	200,637	6.7	0.87	NR	NR
Alexander et al, 1994¹²⁷	50-64	9.4	79	17,149	162,465	4.9	85	15,748	147,233	5.8	0.85	0.62	1.15
Roberts et al, 1990¹²⁸	50-64	6.7	55	17,313	117,095	4.7	63	16,094	107,845	5.8	0.80	0.54	1.17

^aNumbers in bold are calculated from data in the spreadsheet; all other numbers were taken from publications.
^bUsed in reference 30.

Note: CI indicates confidence interval; CNBSS, Canadian National Breast Screening Study; FU, follow-up; HIP, Health Insurance Plan of greater New York; NR, not reported; RR, relative risk.

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Appendix Table 2. Data Used in the Analysisa