Table 5. Results of Mammography Trials Among Women Younger Than 50
Studies of Mammography Alone
| Study (reference) |
Ages |
Median followup (years) |
Number of breast cancer deaths/ total number of women (Screened) |
Number of breast cancer deaths/ total number of women (Control) |
Breast cancer death rate per 1,000 women (Screened) |
Breast cancer death rate per 1,000 women (Control) |
Relative risk for breast cancer death (95% Confidence Interval) |
Absolute risk reduction per 1,000 women |
Number needed to invitea |
Followup year controls screened |
|
Stockholm23 |
40-49 |
14.3 |
34/14,842 |
13/7,103 |
2.29 |
1.83 |
1.52 (0.8-2.88) |
No reduction |
- |
5 |
|
Gothenburg23 |
39-49 |
12.7 |
22/11,724 |
46/14,217 |
1.88 |
3.24 |
0.58 (0.35-0.96) |
1.36 |
736 |
7 |
|
Malmö23 |
45-50 |
13.3 |
53/13,568 |
66/12,279 |
3.91 |
5.38 |
0.73 (0.51-1.04) |
1.47 |
681 |
4 |
|
Swedish Two-County Trial16 |
40-49 |
13 |
45/19,844 |
39/15,604 |
2.27 |
2.50 |
0.87 (0.54-1.41) |
0.23 |
4316 |
7-8 |
Studies of Mammography Plus CBE
| Study (reference) |
Ages |
Median followup (years) |
Number of breast cancer deaths/ total number of women (Screened) |
Number of breast cancer deaths/ total number of women (Control) |
Breast cancer death rate per 1,000 women (Screened) |
Breast cancer death rate per 1,000 women (Control) |
Relative risk for breast cancer death (95% Confidence Interval) |
Absolute risk reduction per 1,000 women |
Number needed to invitea |
Followup year controls screened |
|
CNBSS-122 |
40-49 |
13 |
105/25,214 |
108/25,216 |
4.16 |
4.28 |
0.97 (0.74-1.27) |
0.12 |
- |
- |
|
HIP19,27 |
40-49 |
14 |
64/13,740 |
82/13,740 |
4.66 |
5.97 |
0.78 (0.56-1.08) |
1.31 |
763 |
- |
|
Edinburgh18 |
45-49 |
13 |
49/11,749 |
53/10,267 |
4.17 |
5.16 |
0.75 (0.48-1.18) |
0.99 |
1008 |
6-10 |
aNumber needed to invite for screening to prevent one breast cancer death after 11-16 years.
Note: CBE indicates clinical breast examination; CNBSS, Canadian National Breast Screening Study; HIP, Health Insurance Plan of Greater New York.
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