Appendix Table 1. Key Questions for Screening for Dementia Syndrome
Is there direct evidence from a randomized controlled trial (RCT) of screening that screening for dementia improves health outcomes?
How common is undiagnosed dementia?
How accurate are the screening tests?
What is the added efficacy of initiating the pharmacologic treatments below at screening detection compared with clinical detection in improving health outcomes?
Antihypertensives and aspirin for vascular dementia.
Cholinesterase inhibitors for Alzheimer's disease.
Other drugs (e.g., ginkgo biloba, selegiline, vitamin E, estrogen) for Alzheimer's disease.
Neuroleptics.
Antidepressants.
What is the efficacy of nonpharmacologic interventions for people with mild to moderate dementia and their caregivers?
Does earlier knowledge of the diagnosis of dementia improve patient and family planning for future care and safety?
540 Gaither Road Rockville, MD 20850