Screening Adults for Type 2 Diabetes: A Review of the Evidence

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Key Question	Eligibility Criteria	Number of Articles
Key Question	Eligibility Criteria	Identified for Abstract Review	Meeting Criteria
All	Published 1/1/94 - 7/30/02 English Language MEDLINE®, Cochrane Human subjects
1. Efficacy of screening (direct evidence)	RCT of screening	130	0
2. Accuracy and reliability of screening tests	Population relevant to primary care Screening test offered to all Screening test compared to a valid reference standard, including all positive tests and at least a sample of negatives	487	7
3. Efficacy of knowledge of diabetes status for optimizing the following treatments:
Tight glycemic control	RCT Followup ≥2 years ≥75% of patients followed Health outcomes	436	5
Tight blood pressure control;		426	13
Type of drug
Lipid an aspirin treatment		191	8
Foot care programs		48	2
Counseling for lifestyle change		6	0
4. Lifestyle intervention for people with impaired fasting glucose/impaired glucose tolerance	RCT Intervention at impaired fasting glucose/impaired glucose tolerance stage Valid measure of development of diabetes	39	8
5. Harms of screening and treatment	Use of valid measurement instrument Followup for at least 12 months during treatment Comparison with similar untreated or unscreened control group	57	6

Note: RCT = Randomized controlled trial.