Appendix Figure 2. Histograms of Cost-effectiveness Ratios Resulting from Probabilistic Sensitivity Analyses Based on Universal and Targeted Screening

Cost-Effectiveness Ratios Resulting from 1,000 Targeted Screening Trials	Cost-Effectiveness Ratios Resulting From 1,000 Universal Screening Trials, When Compared With Targeted Screening

A probabilistic sensitivity analysis was conducted in which 129 critical parameters were simultaneously varied over probability distributions based on published 95% confidence intervals or other reasonable ranges. A cost-effectiveness ratio was computed for each of 1,000 iterations for both targeted and universal screening of people aged 55 years. These histograms present the distribution of those ratios.

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