Figure 3. Key Questions

Potential Benefits

Does HRT reduce risks for:

1. Coronary heart disease and cardiovascular disease incidence?
2. Coronary heart disease and cardiovascular disease mortality?
3. Stroke incidence?
4. Stroke mortality?
5. Colorectal cancer?
6. Low bone density?
7. Fractures?
8. Decline in cognitive function?
9. Dementia?

Potential Harms

Does HRT increase risks for:

1. Venous thromboembolism (deep vein thrombosis and pulmonary embolism)?
2. Breast cancer incidence?
3. Breast cancer mortality?
4. Endometrial cancer?
5. Cholecystitis?

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