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Appendix Table 1. Screening for Obesity: Eligibility Criteria and Results of Searches

Key Question Eligibility Criteria Number of Articles
Meeting Eligibility
Criteria and Not
in Prior Systematic
Reviewa
Efficacy of screening RCT
Mass screening
0
Epidemiology of obesity
   a. Prevalence Large U.S. population-based surveys 1
   b. Health risks Prospective cohort studies with absolute rates of health risk reported over ≥10 yrs 14
Efficacy of treatment for weight
reduction or intermediate outcomes
   a. Counseling and behavioral treatment - RCT (of fair or good quality)
- Outcome: weight loss or BMI reduction; glucose tolerance, blood pressure, lipid disorders
- Duration: ≥1 yr
- BMI ≥25 kg/m2
- 12 month followup
21
   b. Medications - RCT (of fair or good quality)
- Outcome: weight loss or BMI reduction; glucose tolerance, blood pressure, lipid disorders
- Duration: ≥6 mos
- Population: generalizable to typical U.S. primary care population
10
   c. Surgery - RCT (of fair or good quality)
- Outcome: weight loss or BMI reduction; glucose tolerance, blood pressure, lipid disorders
- Duration: ≥1 year
- Cohort
- Initial BMI ≥25 kg/m2
- Surgical procedure
2
Harms of screening and treatment Same studies as efficacy of counseling/behavioral and medication interventions
For surgery, same studies as efficacy plus multiple cohorts and 1 non-RCT
21 counseling
15 medication
2 surgery

Notes: RCT = randomized controlled trial; BMI = body mass index
a References 11,28,29,31

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