Table 1. Annual Outcomes of Ovarian Cancer Screening in a Hypothetical Cohort of 10,000 Women Aged 50 to 64 Assuming 40% Mortality Reduction and an Annual Incidence of 40 Per 100,000*
| Women Screened and Predictive Value of Interventions |
CA 125 |
Transvaginal Ultrasound |
| Number of women participating in screening program |
10,000 | 10,000 |
| Screening interval |
Annual | Every 2 years |
| Number of screening tests carried out per year |
10,000 | 5,000 |
| Number of women recalled for further assessment per year who do not have primary ovarian cancer |
300 (3% of screens) | 350 (7% of screens) |
| Number of women undergoing surgery per year who do not have primary ovarian cancer |
20 (0.2% of screens) | 65 (1.3% of screens) |
| Maximum number of cancers detected by screening per year (if 100% sensitivity) |
4 | 4 |
| Number of additional 5-year survivors per year |
1.5 | 1.5 |
| Predictive value of recall (if 100% sensitivity) |
1.3% | 1.1% |
| Predictive value of diagnostic surgery (if 100% sensitivity) |
17% | 5.8% |
| * Adapted from Bell, et al., 1998.32 |
Return to Document
|
540 Gaither Road Rockville, MD 20850