| Williams et al, 20022 |
Yes/no
Pseudo-random (last digit in day of mother's date of birth)
Orthoptists had no knowledge of what group the children were in, rules of allocation, or child's screening history |
Not known
Completers more likely to have educated mothers, not teenaged mothers, live in owner occupied residence, breast fed for at least 3 mos, family history of strabismus or sight problems, weighed > 2,500 grams (P < 0.001); not known how comparable between groups |
Yes
1,088/2,029: 54% of intensive screening group completed study,
826/1,490: 55% of control group completed study |
Yes |
Yes |
Yes |
Yes |
Fair |
| Williams et al, 20013 |
Yes/no
Pseudo-random (last digit in day of mother's date of birth)
Orthoptists had no knowledge of what group the children were in, rules of allocation, or child's screening history |
Intensive group slightly less affluent than controls; attendees more affluent than non-attendees in each group |
Yes
54% of intensive group and 64% of control group attended the final assessment at 37 mos; 31% of intensive group and 35% of control group never attended an assessment |
Yes |
Yes |
Yes |
Yes |
Fair |
| Pediatric Eye Disease Group, 20024 |
Yes
Permuted-block design |
Yes |
No
97% followup patch; 98% atropine |
Yes
Primary visual acuity outcome measure was masked in 97% of cases |
Yes |
Yes |
Yes |
Good |
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