Prepared by:
RTI International
Malaz Boustani, M.D., M.P.H.
Britt Peterson, M.D., M.P.H.
Russell Harris, M.D., M.P.H.
Linda J. Lux, M.P.A.
Carol Krasnov
Sonya F. Sutton, B.S.P.H.
Laura Hanson, M.D., M.P.H.
Kathleen N. Lohr, Ph.D.
File Name Description Software Version File Size _____________________________________________________________________________________________________ 01front.doc Microsoft Word® Document MS Word® 2002 39KB 5 pages Contents: Cover, Title Page, Preface _____________________________________________________________________________________________________ 02abstr.doc Microsoft Word® Document MS Word® 2002 26KB 5 pages Contents: Structured Abstract: Objective, Data Sources, Study Selection, Data Extraction, Data Synthesis, Conclusion _____________________________________________________________________________________________________ 03conts.doc Microsoft Word® Document MS Word® 2002 40KB 3 pages Contents: Table of Contents _____________________________________________________________________________________________________ 04chap1.doc Microsoft Word® Document MS Word® 2002 59KB 8 pages Contents: Chapter 1. Introduction: Background, Burden of Suffering, Epidemiology, Treatment Modalities, Organization of this Systematic Evidence Review _____________________________________________________________________________________________________ 05chap2.doc Microsoft Word® Document MS Word® 2002 32KB 5 pages Contents: Chapter 2. Methods: Analytic Framework and Key Questions; Inclusion/Exclusion Criteria for Admissible Evidence; Literature Search Strategy, Data Extraction, and Synthesis; Development of the Final Systematic Evidence Review _____________________________________________________________________________________________________ 06fig1.doc Microsoft Word® Document MS Word® 2002 575KB 1 page Contents: Figure 1. Screening for Dementia: Analytic Framework _____________________________________________________________________________________________________ 07tbl1.doc Microsoft Word® Document MS Word® 2002 609KB 5 pages Contents: Table 1. Inclusion Criteria, Search Strategy, and Results of Searches _____________________________________________________________________________________________________ 08chap3.doc Microsoft Word® Document MS Word® 2002 1.4MB 43 pages Contents: Chapter 3. Results: Key Question No. 1: Efficacy of Screening; Key Question No. 2: Prevalence of Undiagnosed Dementia and the Common Causes of Dementia; Key Question No. 3: Validity and Reliability of Screening Tests; Key Question No. 4: Efficacy of Pharmacologic Interventions; Key Question No. 5: Efficacy of Nonpharmacologic Interventions; Key Question No. 6: Efficacy of Caregiver Interventions; Key Question No. 7: Adverse Effects of Screening; Key Question No. 8: Costs of Screening; Key Question No. 9: Adverse Effects of Treatment _____________________________________________________________________________________________________ 09tbl2.doc Microsoft Word® Document MS Word® 2002 578KB 1 page Contents: Table 2. Estimates of Undiagnosed Dementia in Primary Care Practices _____________________________________________________________________________________________________ 10tbl3.doc Microsoft Word® Document MS Word® 2002 577KB 1 page Contents: Table 3. Estimates of the Prevalence of Dementia _____________________________________________________________________________________________________ 11tbl4.doc Microsoft Word® Document MS Word® 2002 578KB 1 page Contents: Table 4. Diagnostic Categories for Subtypes of Dementia _____________________________________________________________________________________________________ 12tbl5.doc Microsoft Word® Document MS Word® 2002 580KB 1 page Contents: Table 5. Characteristics and Results of Six Studies Evaluating Properties of the Mini-Mental State Examination _____________________________________________________________________________________________________ 13tbl6.doc Microsoft Word® Document MS Word® 2002 580KB 1 page Contents: Table 6. Likelihood Ratios (LR) for Prediction of Dementia Using the Mini-Mental Status Examination _____________________________________________________________________________________________________ 14tbl7.doc Microsoft Word® Document MS Word® 2002 568KB 1 page Contents: Table 7. Reliability Data for Mini-Mental Status Examination _____________________________________________________________________________________________________ 15tbl8.doc Microsoft Word® Document MS Word® 2002 575KB 1 page Contents: Table 8. Likelihood Ratios (LR) for Prediction of Dementia with Instrumental Activities of Daily Living (IADL) _____________________________________________________________________________________________________ 16tbl9.doc Microsoft Word® Document MS Word® 2002 571KB 1 page Contents: Table 9. Summary Description of Three Common Scales Used in Alzheimer's Disease Drug Trials _____________________________________________________________________________________________________ 17tbl10.doc Microsoft Word® Document MS Word® 2002 573KB 1 page Contents: Table 10. Specific Domains of Basic and Instrumental Activities of Daily Living _____________________________________________________________________________________________________ 18tbl11.doc Microsoft Word® Document MS Word® 2002 571KB 1 page Contents: Table 11. Efficacy of Cholinesterase Inhibitors in Alzheimer's Disease _____________________________________________________________________________________________________ 19chap4.doc Microsoft Word® Document MS Word® 2002 1.2MB 9 pages Contents: Chapter 4. Discussion: Major Findings, Limitations of this Literature, Benefits and Harms, Future Research Needs _____________________________________________________________________________________________________ 20refs.doc Microsoft Word® Document MS Word® 2002 85KB 9 pages Contents: References _____________________________________________________________________________________________________ 21appa.doc Microsoft Word® Document MS Word® 2002 745KB 2 pages Contents: Appendix A. Acknowledgments _____________________________________________________________________________________________________ 22appb.doc Microsoft Word® Document MS Word® 2002 2.0MB 52 pages Contents: Appendix B. Evidence Tables: Glossary of Tests and Terms; Evidence Table 1. Prevalence of Undiagnosed Dementia; Evidence Table 2a. Effectiveness of Screening Tools: Systematic Review; Evidence Table 2b. Effectiveness of Screening Tools: Individual Studies; Evidence Table 3. Longitudinal Studies of the Treatment of Potentially Reversible Dementia; Evidence Table 4a. Efficacy of Cholinesterase Inhibitors in Treatment of Alzheimer's Disease -- Systematic Reviews; Evidence Table 4b. Efficacy of Cholinesterase Inhibitors in Treatment of Alzheimer's Disease -- Studies; Evidence Table 5. Studies of the Efficacy of Gingko Biloba in Treatment of Alzheimer's Disease; Evidence Table 6. Efficacy of Anti-Oxidants and Estrogen in Treatment of Alzheimer's Disease; Evidence Table 7. Efficacy of Anti-Inflammatory Medications in Treatment of Alzheimer's Disease; Evidence Table 8. Studies of the Treatment of Vascular Dementia; Evidence Table 9a: Efficacy of Pharmacologic Interventions for Behavioral Problems Related to Dementia: Systematic Reviews; Evidence Table 9b: Efficacy of Pharmacologic Intervention for Behavioral Problems Related to Dementia: Randomized Controlled Trials; Evidence Table 10: Efficacy of Nonpharmacologic Intervention for Behavioral Problems Related to Dementia: Systematic Reviews; Evidence Table 11a. Efficacy of Caregiver Interventions: Systematic Review; Evidence Table 11b. Efficacy of Caregiver Interventions: Studies; Evidence Table 12a. Adverse Effects of Dementia Therapy: Cholinesterase Inhibitors -- Systematic Reviews; Evidence Table 12b. Adverse Effects of Dementia Therapy: Cholinesterase Inhibitors -- Studies; Evidence Table 12c. Adverse Effects of Dementia Therapy: Typical and Atypical Neuroleptics; Evidence Table 12d. Adverse Effects of Dementia Therapy: Other _____________________________________________________________________________________________________ 23appc.doc Microsoft Word® Document MS Word® 2002 571KB 4 pages Contents: Appendix C. Summary Description of the Scales Used in Dementia Intervention Trials: Alzheimer's Disease Functional Assessment of Change Scale (ADFACS); Clinical Dementia Rating Scale (CDR); Gottfries-Brane-Steen Scale (GBS); Interview for Deterioration in Daily living in Dementia Scale (IDDD); Neuropsychiatry Inventory Scale (NPI); Progressive Deterioration Scale (PDS); Resource Utilization in Dementia Questionnaire Scale (RUD) _____________________________________________________________________________________________________
Current as of June 2003
Internet Citation:
Screening for Dementia. File Inventory, Systematic Evidence Review Number 20. June 2003. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/prev/demeninv.htm
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