Systematic Evidence Review Number 12

Hormone Replacement Therapy and Osteoporosis

File Inventory


Prepared by:

Oregon Health Sciences University Evidence-based Practice Center, Portland, Oregon
   Heidi Nelson, M.D., M.P.H.


File Name		Description			Software	Version		File	Size
__________________________________________________________________________________________________________
01front.doc		Microsoft Word® Document	MS Word®	2002		37KB	5 pages
Contents: Front Cover, Title Page, Preface
__________________________________________________________________________________________________________
01front.doc		Microsoft Word® Document	MS Word®	2002		37KB	5 pages
Contents: Front Cover, Title Page, Preface

02abstr.doc		Microsoft Word® Document	MS Word®	2002		23KB	2 pages
Contents: Structured Abstract: Context, Objective, Data Sources, Study Selection, Data Extraction, 
Data Synthesis, Conclusions

03conts.doc		Microsoft Word® Document	MS Word®	2002		26KB	2 pages
Contents: Table of Contents

04body.doc		Microsoft Word® Document	MS Word®	2002		126KB	28 pages
Contents: Systematic Evidence Review: Chapter 1. Introduction—Burden of Suffering, 
Healthcare Interventions, Prior Recommendations, Analytic Frameworks and Key Questions; 
Chapter 2. Methods—Literature Search Strategy, Inclusion/Exclusion Criteria, Literature Synthesis; 
Chapter 3. Results—Arrow 1. Does hormone replacement therapy improve or stabilize bone density?, 
  Arrow 2. Does hormone replacement therapy prevent osteoporatic fractures?, 
  Arrow 1.  Does postmenopausal use of SERMs improve or stabalize bone density?, 
  Arrow 2.  Does postmenopausal use of SERMs prevent osteoporatic fractures?; 
Chapter 4. Discussion—Conclusions, Limitations of the Literature, Future Research; 
Acknowledgements; References

05fig1&2.ppt	Microsoft PowerPoint® Presentation	MS PowerPoint®	2002		38KB	2 pages
Contents: Figure 1. Analytic Framework 1: Benefits of Hormone Replacement Therapy; 
Figure 2. Analytic Framework 2: Adverse Effects of Hormone Replacement Therapy

06tbl1.xls		Microsoft Excel® Worksheet	MS Excel®	2002		15KB	1 page
Contents: Table 1. Key Questions and Types of Studies Cited

07tbl2.xls		Microsoft Excel® Worksheet	MS Excel®	2002		16KB	1 page
Contents: Table 2. Combined Results of Randomized Controlled Trials of HRT with Bone Density Outcomes

08tbl3.xls		Microsoft Excel® Worksheet	MS Excel®	2002		19KB	2 pages
Contents: Table 3. Randomized Controlled Trials of HRT with Fracture Outcomes

09tbl4.xls		Microsoft Excel® Worksheet	MS Excel®	2002		22KB	4 pages
Contents: Table 4. Cohort Studies of HRT with Hip Fracture Outcomes

10tbl5.xls		Microsoft Excel® Worksheet	MS Excel®	2002		21KB	2 pages
Contents: Table 5. Randomized Controlled Trials of SERMs with Bone Density Outcomes

11tbl6.xls		Microsoft Excel® Worksheet	MS Excel®	2002		18KB	2 pages
Contents: Table 6. Randomized Controlled Trials of SERMs with Fracture Outcomes

12tbl7.xls		Microsoft Excel® Worksheet	MS Excel®	2002		17KB	1 page
Contents: Table 7. Summary of Evidence

13app1a.doc		Microsoft Word® Document	MS Word®	2002		24KB	1 page
Contents: Appendix 1a. Search Strategy for Hormone Replacement Therapy with Bone Density 
or Fractures Outcomes

14app1b.doc		Microsoft Word® Document	MS Word®	2002		26KB	1 page
Contents: Appendix 1b. Search Strategy for Randomized Controlled Trials of Estrogen and SERMs

15app2.doc		Microsoft Word® Document	MS Word®	2002		26KB	1 page
Contents: Appendix 2. Criteria for Grading the Internal Validity of Individual Studies
__________________________________________________________________________________________________________

Current as of September 2002


Internet Citation:

Hormone Replacement Therapy and Osteoporosis. File Inventory, Systematic Evidence Review Number 12. September 2002. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/prev/hrtosinv.htm


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