Figure 1. Analytic Framework and Key Question

[D] Select for Text Description.

Key Questions:
Arrow 1: Is there direct evidence that screening (and intervention) for overweight in childhood improves age-appropriate behavioral or physiologic measures, or health outcomes?
Arrow 2: a. What are appropriate standards for overweight in childhood and what is prevalence of overweight based on these?
b. What are reliable and valid screening tests for overweight in children/adolescents?
c. Is there a reliable and valid screening test for childhood/adolescent overweight that predicts future adult obesity?
Arrow 3: What are the adverse effects of screening, screening, including labeling? Is screening acceptable to patients?
Arrow 4: Do interventions lead to improved intermediate outcomes, including behavioral, physiologic or weight-related measures?
Arrow 5: Do interventions (behavioral counseling, pharmacotherapy, surgery) lead to improved health outcomes, including decreased morbidity, and/or improved functioning (school attendance, self-esteem and other psychosocial indicators)?
a. What are common behavioral and health system elements of efficacious interventions?
b. Are there differences in efficacy between patient subgroups?
Arrow 6: What are the adverse effects of interventions? Are interventions acceptable to patients?

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