![Chart depicting analytic framework with Key Questions. Go to Text Description [D] for details.](chovfig2.gif)
[D] Select for Text Description.
Key Questions:
Arrow 1: Is there direct evidence that screening (and intervention) for overweight in childhood improves age-appropriate behavioral or
physiologic measures, or health outcomes?
Arrow 2: a. What are appropriate standards for overweight in childhood and what is prevalence of overweight based on these?
b. What clinical screening tests for overweight in childhood are reliable and valid in predicting obesity in adulthood?
c. What clinical screening tests for overweight in childhood are reliable and valid in predicting poor health outcomes in adulthood?
Arrow 3: What are the adverse effects of screening, screening, including labeling?
Is screening acceptable to patients?
Arrow 4: Do weight control interventions (behavioral counseling, pharmacotherapy, surgery) lead to improved intermediate outcomes,
including behavioral, physiologic or weight-related measures?
a. What are common behavioral and health system elements of efficacious interventions?
b. Are there differences in efficacy between patient subgroups?
Arrow 5: Do weight control interventions lead to improved health outcomes, including decreased morbidity, and/or improved functioning (school attendance, self-esteem and other psychosocial indicators)?
Arrow 6: What are the adverse effects of interventions? Are interventions acceptable to patients?
Arrow 7: Are improvements in intermediate outcomes associated with improved health outcomes? (Only evaluated if there is no direct evidence for KQ1 or KQ5 and if there is sufficient evidence for for KQ4.)