Appendix Table. Base-Case Assumptions for Outcomes Tables (Table 4) of Counseling and
One-Time Screening for HIV Infection in Pregnant Womena
| Base-Case Assumptions |
Values Used in Outcomes Table |
Source, Year (Reference) |
| Prevalence of HIV infection |
Low-risk: 0.15%
High-risk: 5% |
CDC, 200226
Lindegren, et al., 19993
Fehrs, et al., 198828
Barbacci, et al., 199029 |
| Accuracy of standard testing |
>99% |
CDC, 199042
CDC, 198941 |
| Proportion of patients receiving test results |
91% |
Joo, et al., 200076
|
| Proportion of patients receiving antiretroviral prophylaxis |
60%-90% |
CDC, 200478
CDC, 200279
Wade, et al., 200480
Fiscus, et al., 200281
Cooper, et al., 200282 |
| Proportion of patients receiving elective cesarean section |
37%-50% |
Fiscus, et al., 200281
Dominguez, et al., 200383
CDC, 200478 |
| Rate of mother-to-child transmission in absence of interventions |
14%-25% |
Working Group on Mother-to-Child Transmission of HIV, 199584
|
| Relative risk for mother-to-child-transmission with highly active antiretroviral therapy compared to no antiretroviral therapy |
0.13(95% CI, 0.06-0.27) |
European Collaborative Study, 200589
|
| Rate of postpartum complications in HIV-infected women delivering vaginally |
10.3%(95% CI, 8.39%-12.6%) |
Read, et al., 2001132
|
| Relative risk for postpartum complications from elective cesarean section |
2.62%(95% CI, 1.61%-4.20%) |
Read, et al., 2001132
|
aCDC = Centers for Disease Control and Prevention.
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