| Base-Case Assumptions | Values Used in Outcomes Table | Source, Year (Reference) |
|---|---|---|
| Prevalence of HIV infection | Low-risk: 0.15% High-risk: 5% |
CDC, 200226 Lindegren, et al., 19993 Fehrs, et al., 198828 Barbacci, et al., 199029 |
| Accuracy of standard testing | >99% | CDC, 199042 CDC, 198941 |
| Proportion of patients receiving test results | 91% | Joo, et al., 200076 |
| Proportion of patients receiving antiretroviral prophylaxis | 60%-90% | CDC, 200478 CDC, 200279 Wade, et al., 200480 Fiscus, et al., 200281 Cooper, et al., 200282 |
| Proportion of patients receiving elective cesarean section | 37%-50% | Fiscus, et al., 200281 Dominguez, et al., 200383 CDC, 200478 |
| Rate of mother-to-child transmission in absence of interventions | 14%-25% | Working Group on Mother-to-Child Transmission of HIV, 199584 |
| Relative risk for mother-to-child-transmission with highly active antiretroviral therapy compared to no antiretroviral therapy | 0.13(95% CI, 0.06-0.27) | European Collaborative Study, 200589 |
| Rate of postpartum complications in HIV-infected women delivering vaginally | 10.3%(95% CI, 8.39%-12.6%) | Read, et al., 2001132 |
| Relative risk for postpartum complications from elective cesarean section | 2.62%(95% CI, 1.61%-4.20%) | Read, et al., 2001132 |
aCDC = Centers for Disease Control and Prevention.