Table 1. The Leading and Actual Causes of Death, United States, 2000

Leading cause of death	Rate/100,000	Actual cause of death	No. (%)
Heart disease	258.2	Tobacco	435,000 (18.1)
Malignant neoplasm	200.9	Poor diet and physical activity	400,000 (16.6)
Cerebrovascular disease	60.9	Alcohol consumption	85,000 (3.5)
Chronic lower respiratory tract disease	44.3	Microbial agents	75,000 (3.1)
Unintentional injuries	35.6	Toxic agents	55,000 (2.3)
Diabetes mellitus	25.2	Motor Vehicle	43,000 (1.8)
Influenza and pneumonia	23.7	Firearms	29,000 (1.2)
Alzheimer disease	18.0	Sexual behavior	20,000 (0.8)
Nephritis, nephritic syndrome, and nephrosis	13.5	Illicit drug use	17,000 (0.7)
Septicemia	11.3
Other	181.4
Total	873.1	Total	1,159,000 (48.2)

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*From: Mokdad AH, Marks JS, Stroup DF Gerberding JL. Actual causes of death in the United States, 2000. JAMA 2004;291:1238-1245. See also the correction in JAMA 2005;293:293-294.

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Table 2. The Clinical and Community Guides Review Complementary Interventions

Prevention Strategy	Task Force
Clinical    Screening, Counseling, Preventive Medication	US Preventive Services Task Force
Health System Change	Task Force on Community Preventive Services
Community    Group Education    Policy Change    Environmental Change

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