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Appendix Table 2. Specific Searches per Key Question*


Key Question Search Strategy
1—Screening 1) exp VAGINOSIS, BACTERIAL/di
2) vaginosis.mp.
3) exp Pregnancy Complications, Infectious/di, ep
4) 2 and 3
5) exp PREGNANCY COMPLICATIONS/ or exp PREGNANCY/
6) 1 and 5
7) exp mass screening/ or screen$.mp.
8) pregnan$.mp. [mp=title, original title, abstract, name of substance word, subject heading word]
9) 7 and 8
10) 2 and 9
11) 4 or 6 or 10
12) limit 11 to yr="2000-2006"
13) limit 12 to humans
14) limit 13 to English language
15) limit 13 to abstracts
16) 14 or 15
2—Treatment 1) exp VAGINOSIS, BACTERIAL/dt, th [Drug Therapy, Therapy]
2) vaginosis.mp.
3) exp Pregnancy Complications, Infectious/dt, th, pc
4) 2 and 3
5) exp fetal membranes, premature rupture/dt, th, pc or exp labor, premature/dt, th, pc
6) 2 and 5
7) exp PREGNANCY COMPLICATIONS/ or exp PREGNANCY/
8) 1 and 7
9) 4 or 6 or 8
10) limit 9 to yr="2000-2006"
11) limit 10 to humans
12) limit 11 to English language
13) limit 11 to abstracts
14) 12 or 13
3—Adverse Effects 1) exp pregnancy/ or exp pregnancy complications/ or exp Embryonic Structures/de
2) ((adverse$ adj5 effect$) or harm or harmed or harms or harming or defect$ or malform$).mp. [mp=title, original title, abstract, name of substance word, subject heading word]
3) clindamycin.mp. or exp Clindamycin
4) metronidazole.mp. or exp Metronidazole
5) (ae or to or po).fs.
6) 2 or 5
7) 3 or 4
8) 1 and 6 and 7
9) vaginosis.mp.
10) exp Anti-Bacterial Agents
11) exp Bacterial Infections/dh, dt, th [Diet Therapy, Drug Therapy, Therapy]
12) 10 or 11
13) 9 and 12
14) 1 and 6 and 13
15) 8 or 14
16) limit 15 to (humans and English language)

*Database: Ovid MEDLINE®.

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