Summaries of Independent Scientist (K) Awards

Linder, Jeffrey

Institution: Brigham and Women's Hospital
Grant Title: Improving Care for Acute Respiratory Infections
Grant Number:  K08 HS014563
Duration: 5 years (2004-2009)
Total Award: $669,600

Project Description: This project has four main goals:

1. To develop the Acute Respiratory Infection (ARI) Smart Set Form, which will standardize documentation of care and give providers easy access to clinical information, on-line decision support, and patient education materials.
2. To perform a randomized controlled trial (RCT) of the ARI Smart Set Form to assess its effectiveness in decreasing antibiotic prescribing in primary care practices.
3. To connect the ARI Smart Set  Form with a national disease surveillance program, the National Bioterrorism Syndromic Surveillance Demonstration Project, to provide an automated, bi-directional link between the personal and public health systems.
4. To perform an RCT of providing clinicians with point-of-care, real-time data about the prevalence of influenza and other respiratory illnesses in an individual patient's neighborhood through the ARI Smart Set Form. 

Career Goals: Dr. Linder is an academic general internist.  He plans to develop a multidisciplinary research program to improve the care of patients with acute respiratory infections (ARIs) while improving links between the private and public health systems to provide surveillance for naturally occurring disease clusters and bioterrorism.  Dr. Linder's multidisciplinary training regimen will include acquiring new skills in informatics, advanced biostatistics, patient safety, research ethics, public health, and disease surveillance through participation in local seminars, national scientific meetings, and peer-reviewed publication of results. 

Progress to Date: Dr. Linder performed a randomized controlled trial of the ARI Smart Form in primary care practices affiliated with Brigham and Women's Hospital and Mass General hospital during the flu season.  Data have been aggregated and a manuscript is in preparation.

Future Plans: The grantee will continue submitting manuscripts for publication.  He will implement the ARI Smart Form and standardize the interface.

Highlights and Specific Accomplishments:

• Professional Societies:
  • Member, American College of Physicians.
  • Member, Society of General Internal Medicine.
• Provisional Medical Staff, Faulkner Hospital, Boston, MA.
• Associate Physician, Brigham and Women's Health, Boston, MA.
• Instructor in Medicine, Harvard Medical School, Boston, MA.
• Excellence in Teaching Award, Harvard Medical School and Harvard School of Dental Medicine, Class of 2006.

K-Generated Publications:

Linder JA, Bates DW, Platt R. Antivirals and antibiotics for influenza in the United States, 1995-2002. Pharmacoepidemiol Drug Safety 2005.

Linder JA, Huang ES, Steinman MA, et al. Fluoroquinolone prescribing in the United States: 1995 to 2002. American  Journal of  Medicine 2005. 118(3):259-68.

Linder JA, Ma J, Bates DW, et al. Electronic health record use and the quality of ambulatory care in the United States. Archives of Internal Medicine 2007. July 9:1400-05.

Linder JA, Schnipper JL, Tsurikova R, et al. Barriers to electronic health record use during patient visits.  AMIA Annual Symposium Proceedings 2006. pp.499-503.

Linder JA, Bates DW, Williams DH, et al. Acute infections in primary care: Accuracy of electronic diagnoses and electronic antibiotic prescribing. Journal of the American Medical Informatics Association 2006. 13(1):61-6

Linder JA, Bates DW, Lee GM, Finkelstein JA. Antibiotic treatment of children with sore throat. Journal of the American Medical Association 2005. 294(18):2315-22.

Linder JA, Chan JC, Bates DW. Appropriateness of antiviral prescribing for influenza in primary care: A retrospective analysis. Journal of Clinical Pharmacy and Therapeutics 2006. 31:245-52.

Farwell WR, Linder JA, Jha AK. Trends in prostate-specific antigen testing from 1995 through 2004. Archives of Internal Medicine 2007. 167(22):2497-502.

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