Slide Presentation from the AHRQ 2008 Annual Conference
On September 10, 2008, Stephanie Chang, made this presentation at the 2008 Annual Conference. Select to access the PowerPoint® presentation (576 KB; Plugin Software Help).
Conducting a Methodologically Sound Systematic Review with Limited Resources: An Introduction
AHRQ Annual Meeting
September 10, 2008
Stephanie Chang MD, MPH
Center for Outcomes and Evidence.
- Understand breadth of methods issues in conducting systematic reviews.
- Identify available resources for methods guidance.
- Identify available resources for conducting a review.
Conducting systematic reviews
- No text—slide shows three pictures of food: a toaster popping up toast, a brown-bag lunch, a dinner table.
Elements of systematic review
- Clarify critical questions.
- Specify appropriate sources of information to address questions.
- Evaluate quality of individual studies.
- Internal and external validity.
- Summarize evidence for each question.
- Qualitative synthesis, Meta-analysis.
- (Decision analysis, Cost-effectiveness).
Methodology of systematic reviews
- Relevant, but independent:
- Engaging partners for Key Questions.
- Engage partners for translation.
- Technical expert panel.
- Comprehensive, rigorous, unbiased:
- Complete literature review.
- Assessment of study quality.
- A priori definitions.
- Peer review.
- Reporting of methods used.
- Methods Guide.
AHRQ Evidence-based Practice Centers
- Blue Cross and Blue Shield (BC/BS) Association, Technology Evaluation Center (TEC)
- University of Connecticut
- Duke University
- Johns Hopkins University
- McMaster University
- University of Minnesota
- Oregon Health and Science University (HSU)
- University of Southern California-RAND
- RTI International-University of North Carolina (UNC)
- University of California San Francisco (UCSF)-Stanford University
- University of Alberta
- University of Ottawa
Methods Guide Resources
- Methods Guide for Conducting Comparative Effectiveness Reviews:
- Topic Development.
- Selecting Evidence.
- Finding Evidence.
- Assessing Quality of individual studies.
- Assessing Applicability.
- Assessing Harms.
- Quantitative Synthesis.
- Rating a body of evidence.
- Cochrane Handbook and Glossary.
- Data Management.
- Evidence Tables.
- Comprehensive Meta-analysis ($):
- Statistical software:
- TrialStat! ($):
Current as of January 2009
Conducting a Methodologically Sound Systematic Review with Limited Resources: An Introduction. Slide Presentation from the AHRQ 2008 Annual Conference (Text Version). January 2009. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/about/annualmtg08/091008slides/Chang.htm