Birth Defects May Be Linked to Hypertension, NOT Treatment
- Taking angiotensin-converting enzyme (ACE) inhibitors in first trimester of pregnancy poses no greater risk of birth defects than other high blood pressure medications or no drugs at all.
- Findings suggest high blood pressure itself may increase risk of birth defects, rather than treatment.
- ACE inhibitors are widely prescribed to treat hypertension.
- New study from Effective Health Care Program's DEcIDE Network published in BMJ.
Li DK, Yang C, Andrade S, et al. Maternal exposure to angiotensin converting enzyme inhibitors in the first trimester and risk of malformations in offspring: a retrospective cohort study. BMJ 2011; 343:d5931
Image: The first page of the cited BMJ article is shown.
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