Evidence-Based Medicine

Current Guidelines Have Limited Applicability to Patients with Comorbid Conditions: A Systematic Analysis of Evidence-Based Guidelines. M. Lugtenberg, J. Burgers, C. Clancy, et al., PLoS ONE, 2011; 6(10):e25987. Epub October 2011. Assesses the extent to which guidelines address comorbidity and the supporting evidence of recommendations related to comorbidity. (AHRQ 12-R021

Grading the Strength of a Body of Evidence when Comparing Medical Interventions—Agency for Healthcare Research and Quality and the Effective Health Care Program. AHRQ Series Paper 5. D. Owens, K. Lohr, D. Atkins, et al., Journal of Clinical Epidemiology; May 2010; 63(5):513-523. Establishes guidance on grading strength of evidence for AHRQ's Evidence-based Practice Center (EPC) program. (AHRQ 10-R070)

Additional Reports and Technical Reviews Only the most recent Evidence Reports/Technology Assessments are listed here. Information about all available reports, as well as publications in AHRQ's Technical Review series, is available online. Go to www.ahrq.gov/clinic/epcix.htm on the AHRQ Web site for the Evidence Reports/ Technology Assessments and http://www.ahrq.gov/clinic/tp/nutrseries.htm to access the Technical Reviews.

Evidence Reports/Technology Assessments

Cancer and Blood Disorders

Alcohol Consumption and Cancer Risk: Understanding Possible Causal Mechanisms for Breast and Colorectal Cancers.
Evidence Report/Technology Assessment No. 197.
Evidence Report. November 2010 (AHRQ 11-E003)

Enhancing the Use and Quality of Colorectal Cancer Screening.
Evidence Report/Technology Assessment No. 190.
Evidence Report. February 2010 (AHRQ 10-E002)

An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer.
Evidence Report/Technology Assessment No. 204.
Executive Summary. December 2011 (AHRQ 12-E003-1)

Multigene Panels in Prostate Cancer Risk Assessment.
Evidence Report/Technology Assessment No. 209.
Executive Summary. July 2012 (AHRQ 12-E020-1)

Complementary and Alternative Care

Complementary and Alternative Therapies for Back Pain II.
Evidence Report/Technology Assessment No. 194.
Evidence Report. October 2010 (AHRQ 10(11)-E007)

Dietary Supplements

Safety of Probiotics to Reduce Risk and Prevent or Treat Disease.
Evidence Report/Technology Assessment No. 200.
Executive Summary. April 2011 (AHRQ 11-E007-1)

Ear, Nose, and Throat Conditions

Exercise-Induced Bronchoconstriction and Asthma.
Evidence Report/ Technology Assessment No. 189
Evidence Report. January 2010 (AHRQ 10-E001)

Management of Acute Otitis Media: Update.
Evidence Report/Technology Assessment No. 198.
Evidence Report. December 2010 (AHRQ 11-E004)

Heart and Vascular Diseases

Transition of Care for Acute Stroke and Myocardial Infarction Patients: From Hospitalization to Rehabilitation, Recovery, and Secondary Prevention.
Evidence Report/Technology Assessment No. 202.
Executive Summary. October 2011 (AHRQ 11(12)-E011-1)

Infectious Diseases

Management of Chronic Hepatitis B.
Evidence Report/Technology Assessment No. 174.
Evidence Report. October 2008 (AHRQ 09-E002)

Information Technology

Enabling Medication Management Through Health Information Technology.
Evidence Report/Technology Assessment No. 201.
Executive Summary. April 2011 (AHRQ 11-E008-1)

Enabling Patient-Centered Care Through Health Information Technology.
Evidence Report/Technology Assessment No. 206.
Executive Summary. June 2012 (AHRQ 12-E005-1)

Laboratory Testing

Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs.
Evidence Report/Technology Assessment No. 196.
Evidence Report. December 2010 (AHRQ 11-E002)

Mental Health Conditions and Substance Abuse

Preventing Alzheimer's Disease and Cognitive Decline.
Evidence Report/Technology Assessment No. 193.
Evidence Report. July 2010 (AHRQ 10-E005)

Obstetric and Gynecologic Conditions

Inhaled Nitric Oxide in Preterm Infants.
Evidence Report/Technology Assessment No. 195.
Evidence Report. October 2010 (AHRQ 11-E001)

Vaginal Birth After Cesarean: New Insights.
Evidence Report/Technology Assessment No. 191.
Evidence Report. March 2010 (AHRQ 10-E001)

Oral and Gastrointestinal Disorders

Lactose Intolerance and Health.
Evidence Report/Technology Assessment No. 192.
Evidence Report. February 2010 (AHRQ 10-E004)

Pediatric Conditions

Diagnosis and Management of Febrile Infants (0-3 months).
Evidence Report/Technology Assessment No. 205.
Executive Summary. March 2012 (AHRQ 12-E004-1)

Quality Improvement and Patient Safety

Closing the Quality Gap: Revisiting the State of the Science.
Evidence Report/Technology Assessment No. 208.
Comprises a series of eight papers, published as they become available, on various quality improvement strategies.
Paper No. 2. The Patient Centered-Medical Home.
Executive Summary. July 2012 (AHRQ 12-E008-1)
Paper No. 3. Quality Improvement Interventions to Address Health Disparities.
Executive Summary. August 2012 (AHRQ 12-E009-1)
Paper No. 5. Public Reporting as a Quality Improvement Strategy.
Executive Summary. July 2012 (AHRQ 12-E011-1)

Health Literacy Interventions and Outcomes: An Updated Systematic Review.
Evidence Report/Technology Assessment No. 199.
Executive Summary. March 2011 (AHRQ 11-E006-1)

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