EHC Program Inside Track Newsletter
In this issue:
- EHC Program Offers "Clinical Bottom Line" on Conditions Linked to Kidney Disease
- More New, Free Effective Health Care Program Resources
EHC Program Offers "Clinical Bottom Line" on Conditions Linked to Kidney Disease
Today’s clinicians understand that diabetes and high blood pressure increase patients’ risks for developing kidney disease. In recognition of March as National Kidney Month, AHRQ’s Effective Health Care (EHC) Program is highlighting publications that help health care professionals compare treatments for these conditions and talk to patients about which treatment options are best for them.
Chronic kidney disease (CKD) is often diagnosed as a result of screening people with high blood pressure or diabetes. About 8 percent of the U.S. population has diabetes, and more than 30 percent has high blood pressure, according to Federal estimates. These conditions are the leading causes of kidney disease, together accounting for about two-thirds of all CKD cases. Last year the CDC reported that more than 20 million Americans have kidney disease.
The links below provide access to EHC Program research summaries for clinicians on kidney disease, diabetes, and high blood pressure. The publications summarize evidence from research reviews and offer the “Clinical Bottom Line” on the effectiveness and risks of different treatment options, plus current gaps in knowledge.
Clinicians may also want to access AHRQ’s library of free continuing education activities, as well as plain-language summaries that help consumers understand health conditions and treatment options. In addition, AHRQ offers an array of consumer publications in Spanish that compare treatments for kidney health and related conditions.
- Chronic Kidney Disease Stages 1-3: Screening, Monitoring, and Treatment – Evaluates the evidence regarding the potential benefits and harms of treatment of adults for early stage (1-3) chronic kidney disease(CKD).
- Methods for Delivery Insulin and Measuring Glucose– Explains research on different ways to manage diabetes using insulin methods and glucose monitoring.
- Premixed Insulin Analogues: A Comparison With Other Treatments for Type 2 Diabetes – Summarizes clinical evidence comparing the effectiveness and safety of premixed insulin analogues with other insulin preparations and oral diabetes drugs.
- Comparing Medications for Adults With Type 2 Diabetes – Examines the comparative effectiveness, benefits, and adverse effects of available monotherapy and two-drug combinations of medications for adults with type 2 diabetes.
High Blood Pressure
- Self-Measured Blood Pressure Monitoring – Compares the effectiveness of self-measured blood pressure monitoring and adds to AHRQ’s growing collection of resources on cardiovascular health.
- Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs) and Direct Renin Inhibitors for Treating Essential Hypertension: An Update – Provides an expanded review of the effectiveness and risks of popular hypertension medications. It updates a 2007 AHRQ research review comparing ACEIs and ARBs with new data comparing a third category of treatment—direct renin inhibitors.
More New, Free Effective Health Care Program Resources
New Evidence-Based Treatment Summaries for Patients and Clinicians
Treatment summaries help patients and clinicians learn about treatment options and compare their effectiveness, benefits, and risks. To order free print copies, call 1-800-358-9295 and use reference code C-05.
Glaucoma: Treatment for Open-Angle Glaucoma
New materials are available from AHRQ that compare several types of treatment options for people with glaucoma. The resources compare the effectiveness of these treatments and give health care providers and patients the information they need to help make the best possible decisions. Resources include—
- A patient summary of treatment options
- A clinician research summary that outlines the clinical bottom line
- A CME/CE course for clinicians to receive free continuing education credits
- The full research review
Spanish-Language Patient Resources
- Medicamentos para la artritis psoriásica: Revisión de la investigación para adultos (Drug Therapy for Psoriatic Arthritis in Adults: Update of a 2007 Report)
- Medicamentos para la artritis reumatoide: Revisión de la investigación para adultos (Drug Therapy for Rheumatoid Arthritis in Adults: An Update)
- Progestágenos para prevenir el parto prematuro: Revisión de la investigación sobre el uso de progestágenos en las mujeres con riesgo (Progestogens for the Prevention of Preterm Birth)
- Métodos para administrar insulina y medir el azúcar en la sangre: Revisión de las investigaciones para niños, adolescentes y adultos con diabetes (Methods for Insulin Delivery and Glucose Monitoring: Comparative Effectiveness)
New Research Review Comparing Treatment Options
This review compares available evidence from numerous research studies.
Children Exposed to Trauma: Beneficial Interventions
Certain psychotherapeutic interventions may be beneficial for children exposed to trauma (other than maltreatment or family violence), finds a new review from AHRQ. However, far more research is required to produce definitive guidance on the effectiveness and comparative effectiveness of psychotherapeutic and pharmacological interventions. Some psychotherapy interventions appear promising based on the magnitude and precision of effects found (changes in PTSD, anxiety, depression, or anger symptoms). These interventions are school-based treatments with elements of cognitive behavior therapy. Approximately two-thirds of children and adolescents under the age of 18 will experience at least one traumatic event, creating a critical need to identify effective child trauma interventions. Read the full research review here: Child and Adolescent Exposure to Trauma: Comparative Effectiveness of Interventions Addressing Trauma Other Than Maltreatment or Family Violence.
Other New Research
Observational Comparative Effectiveness Research: New User’s Guide Available in eBook Format
AHRQ’s Effective Health Care Program has released a new user’s guide that identifies best practices for designing observational comparative effectiveness research (CER). Developing a Protocol for Observational Comparative Effectiveness Research: A User’s Guide is intended to serve as a reference for investigators when developing CER research studies. The guide is available in eBook file formats, designed to be read with eBook readers (e.g., Nook, Kindle, iPad), tablets, and smart phones that have an eReading application. Topics include the development of study objectives and questions, study design, data sources, and analysis. A collection of 12 training modules in PowerPoint format is available to augment training in these best practices. Both the user’s guide and training modules are free from the EHC Program. Free print copies of the User’s Guide may be ordered by email from the AHRQ Clearinghouse using publication number 12(13)-EHC099.