Systematic Review: Safety and Efficacy of Extended-duration Antiviral Chemoprophylaxis against Pandemic and Seasonal Influenza

This weekly compilation of articles appearing in recently released journals and newsletters includes:

• Articles funded by the Agency for Healthcare Research and Quality (AHRQ) or authored by AHRQ researchers.
• Articles mentioning or discussing AHRQ staff, activities, and publications/products.
• Articles related to AHRQ-funded Evidence-based Practice Centers.
• Articles related to the U.S. Preventive Services Task Force or Put Prevention into Practice program.
• Articles mentioning the National Healthcare Disparities Report and National Healthcare Quality Report.
• Other research using AHRQ data or products.

AHRQ-Funded/Authored Articles

Annals of Internal Medicine
Khazeni N, Bravata DM, Holty JE, et al. Systematic review: safety and efficacy of extended-duration antiviral chemoprophylaxis against pandemic and seasonal influenza. Ann Intern Med 2009 Oct 6; 151(7):464-73, W-154-W159. [Supported in part by grant 1 F32 HS18003-01A1 (to first author).] Select to access the abstract.

Circulation
Likosky DS, Sorensen MJ, Dacey LJ, et al. Long-term survival of the very elderly undergoing aortic valve surgery. Circulation 2009 Sep 15; 120(11 Suppl):S127-33. [Supported in part by grant 1 K02 HS15663-01A1 (to first author).] Select to access the abstract.

Health Services Research
Burns ME. Medicaid managed care and health care access for adult beneficiaries with disabilities. Health Serv Res 2009 Oct; 44(5 Pt 1):1521-41. [Supported in part by grant T32 HS00083; uses 1996-2004 Medical Expenditure Survey Panel (MEPS) data; author notes that research was conducted at AHRQ's CFACT Data Center.] Select to access the abstract.

Gresenz CR, Rogowski J, Escarce JJ. Community demographics and access to health care among U.S. Hispanics. Health Serv Res 2009 Oct; 44(5 Pt 1):1542-62. [Supported by grant P01 HS10770; uses 1996-2002 MEPS data; authors acknowledge support from Ray Kuntz (researcher in AHRQ's Center for Financing, Access, and Cost Trends) at AHRQ's CFACT Data Center in analyzing the data; cites AHRQ publication, Estimation Procedures in the 1996 MEPS Household Component, MEPS Methodology Report No. 5, 1999; cites AHRQ-authored articles by Cohen, Monheit, Beauregard, Cohen, Lefkowitz, Potter (authors are current and former researchers in AHRQ's Center for Financing, Access, and Cost Trends) et al. (Inquiry, 1996/1997), Kirby, Taliaferro, and Zuvekas (first and third authors are researchers in AHRQ's Center for Financing, Access, and Cost Trends and second author is a researcher in AHRQ's Center for Primary Care, Prevention, and Clinical Partnerships) (Med Care, 2006), Weinick, Jacobs, Stone, Ortega (first and fourth authors are former AHRQ researchers) (Med Care, 2004), and Zuvekas and Taliaferro (Health Aff, 2003).] Select to access the abstract.

Zuvekas SH, Olin GL. Validating household reports of health care use in the Medical Expenditure Panel Survey. Health Serv Res 2009 Oct; 44(5 Pt 1):1679-700. [First author is a researcher in AHRQ's Center for Financing, Access, and Cost Trends; uses and cites 2001-2003 MEPS data; cites AHRQ-authored article by Cohen, Monheit, Beauregard, Cohen, Lefkowitz, Potter et al. (Inquiry, 1996/1997), Cohen (director of AHRQ's Center for Financing, Access, and Cost Trends) and Burt (J Econ Soc Meas, 1985), and Sing,, Banthin, and Selden (researchers in AHRQ's Center for Financing, Access, and Cost Trends) (Health Care Financ Rev, 2006).] Select to access the abstract.

Tsai CL, Clark S, Sullivan AF, et al. Development and validation of a risk-adjustment tool in acute asthma. Health Serv Res 2009 Oct; 44(5 Pt 1):1701-17. [Supported in part by grant R01 HS13099.] Select to access the abstract.

Beckett MK, Elliott MN, Richardson A, et al. Outpatient satisfaction: the role of nominal versus perceived communication. Health Serv Res 2009 Oct; 44(5 Pt 1):1735-49. [Supported in part by grant K02 HS13299-01; describes AHRQ's Consumer Assessment of Healthcare Providers and Systems (CAHPS®) as "the most extensive set of information about health plan and provider performance ... " ; cites AHRQ-authored article by Crofton, Darby, Farquhar, and Clancy (current and former researchers in AHRQ's Center for Quality Improvement and Patient Safety and AHRQ director) (Jt Comm J Qual Patient Saf, 2005), discussing CAHPS' development and use.] Select to access the abstract.

Journal of Infectious Diseases
Lautenbach E. Antimicrobial resistance in gram-negative pathogens: crafting the tools necessary to navigate the long ascent out of the abyss. J Infect Dis 2009 Sep 15; 200(6):838-40. [Supported in part by Centers for Education and Research on Therapeutics cooperative agreement grant U18 HS10399; comments on article by Johnson et al. (J Infect Dis, 2009), cited in AHRQ-Related Articles below.]

Medical Care Research and Review
Onega T, Duell EJ, Shi X, et al. Influence of NCI Cancer Center attendance on mortality in lung, breast, colorectal, and prostate cancer patients. Med Care Res Rev 2009 Oct; 66(5):542-60. [Supported by grant T32 HS00070; cites AHRQ-funded articles by Birkmeyer et al. (N Engl J Med, 2002, JAMA, 2003, and Cancer, 2005), Finlayson, Goodney, and Birkmeyer (Arch Surg, 2003), Grumbach et al. (JAMA, 1995), and others.] Select to access the abstract.

New England Journal of Medicine
Ghaferi AA, Birkmeyer JD, Dimick JB. Variation in hospital mortality associated with inpatient surgery. N Engl J Med 2009 Oct 1; 361(14):1368-75. [Supported in part by career development award grant K08 HS17765 (to third author).] Select to access the abstract.

AHRQ-Related Articles

American Journal of Epidemiology
Lauderdale DS, Knutson KL, Rathouz PJ, et al. Cross-sectional and longitudinal associations between objectively measured sleep duration and body mass index: the CARDIA Sleep Study. Am J Epidemiol 2009 Oct 1; 170(7):805-13. [Cites article by Stranges et al. (Am J Epidemiol, 2008) which used data from the AHRQ-funded Whitehall II study.] Select to access the abstract.

Annals of Family Medicine
Stange KC. A science of connectedness. Ann Fam Med 2009 Sep-Oct; 7(5):387-95. [Cites AHRQ-authored article by Franks, Clancy (AHRQ director), and Nutting (N Engl J Med, 1992); cites AHRQ-funded articles by Greenfield et al. (JAMA, 1992 and 1995).]

Glazier RH, Agha MM, Moineddin R, et al. Universal health insurance and equity in primary care and specialist office visits: a population-based study. Ann Fam Med 2009 Sep-Oct; 7(5):396-405. [Cites article by Marmot et al. (Lancet, 1991), using data from the AHRQ-funded Whitehall II study.] Select to access the abstract.

Annals of Internal Medicine
Friedberg MW, Coltin KL, Gelb Safran D, et al. Associations between structural capabilities of primary care practices and performance on selected quality measures. Ann Intern Med 2009 Oct 6; 151(7):456-63, w146-53. [Cites AHRQ-funded articles by Linder et al. (Arch Intern Med, 2003), Simon et al. (J Am Med Inform Assoc, 2007), and Rosenthal et al. (N Engl J Med, 2006).] Select to access the abstract.

Niederman M. In the clinic. community-acquired pneumonia. Ann Intern Med 2009 Oct 6; 151(7):ITC4-2-14; quiz ITC4-16. [Cites AHRQ-funded article by Aujesky et al. (Am J Med, 2005).]

British Medical Journal
Lewin S, Glenton C, Oxman AD. Use of qualitative methods alongside randomised controlled trials of complex healthcare interventions: methodological study. BMJ 2009 Sep 26; 339(7723):732-34. [Cites AHRQ-funded article by Glasgow, Lichtenstein, and Marcus (Am J Public Health, 2003).] Select to access the abstract.

CMAJ: Canadian Medical Association Journal
Retnakaran R, Shah BR. Mild glucose intolerance in pregnancy and risk of cardiovascular disease: a population-based cohort study. CMAJ 2009 Sep 15; 181(6-7):371-6. [Cites AHRQ-funded article by Deyo, Cherkin, and Ciol (J Clin Epidemiol, 1992).] Select to access the abstract.

Circulation
Bachhuber MA, Lott JP. Letter by Bachhuber and Lott regarding article, "Characteristics of children hospitalized with infective endocarditis". Circulation 2009 Sep 22; 120(12):e94. [Describes and cites 2003 Healthcare Cost and Utilization Project (HCUP) Kids' Inpatient Database (KID) data; see author response by Day et al. cited below.]

Day MD, Gauvreau K, Newburger JW, et al. Response to letter regarding article, "Characteristics of children hospitalized with infective endocarditis". Circulation 2009 Sep 22; 120(12):e95. [Responds to above letter by Bachhuber and Lott commenting on article by Day et al. (Circulation, 2009), which uses 2000 and 2003 HCUP KIDS data.]

Gerontologist
Bishop CE, Squillace MR, Meagher J, et al. Nursing home work practices and nursing assistants' job satisfaction. Gerontologist 2009 Oct; 49(5):611-22. [Cites AHRQ-funded article by Tyler et al. (Health Care Manage Rev, 2006).] Select to access the abstract.

Mittal V, Rosen J, Leana C. A dual-driver model of retention and turnover in the direct care workforce. Gerontologist 2009 Oct; 49(5):623-34. [Cites AHRQ-funded article by Karsh, Booske, and Sainfort (Ergonomics, 2005).] Select to access the abstract.

Health Services Research
Singer SJ, Hartmann CW, Hanchate A, et al. Comparing safety climate between two populations of hospitals in the United States. Health Serv Res 2009 Oct; 44(5 Pt 1):1563-83. [Cites AHRQ-authored articles by Kirby, Taliaferro, and Zuvekas (Med Care, 2006) and Hudson, Miller, and Kirby (first and third authors are researchers in AHRQ's Center for Financing, Access, and Cost Trends) (Med Care, 2007); cites AHRQ-funded article by Pronovost et al. (Qual Saf Health Care, 2003); cites AHRQ publications Advances in Patient Safety: From Research to Implementation, Vol. 1, 2005 and Hospital Survey on Patient Safety Culture: 2007 Comparative Database Report, 2009.] Select to access the abstract.

Hirth RA, Turenne MN, Wheeler JR, et al. Provider monitoring and pay-for-performance when multiple providers affect outcomes: An application to renal dialysis. Health Serv Res 2009 Oct; 44(5 Pt 1):1585-602. [Cites AHRQ publication, Pay for Performance: A Decision Guide for Purchasers, 2006; cites AHRQ-funded articles by Rosenthal et al. (N Engl J Med, 2006) and Zheng et al. (Med Care, 2006).] Select to access the abstract.

Karter AJ, Parker MM, Moffet HH, et al. New prescription medication gaps: a comprehensive measure of adherence to new prescriptions. Health Serv Res 2009 Oct; 44(5 Pt 1):1640-61. [Cites AHRQ-funded article by Ray (Am J Epidemiol, 2003).] Select to access the abstract.

Pérez DJ, Larkin MA. Commentary: partnership for the future of public health services and systems research. Health Serv Res 2009 Oct; 44(5 Pt 2):1788-95. [Asserts the need for AHRQ and other federal agencies "to invest their fair share in public health services and systems research so that we can answer critical questions that relate to how we can improve the health of Americans" .]

Mays GP, Smith SA. Geographic variation in public health spending: correlates and consequences. Health Serv Res 2009 Oct; 44(5 Pt 2):1796-817. [Cites AHRQ-authored publication by Brown, Elixhauser (researcher in AHRQ's Center for Delivery, Organization, and Markets) et al., National Expenditures for Health Promotion and Disease Prevention Activities in the United States, 1991 (published by Batelle Medical Technology Assessment and Policy Research Center).] Select to access the abstract.

Journal of Infectious Diseases
Johnson JK, Smith G, Lee MS, et al. The role of patient-to-patient transmission in the acquisition of imipenem-resistant Pseudomonas aeruginosa colonization in the intensive care unit. J Infect Dis 2009 Sep 15; 200(6):900-5. [Cites AHRQ-funded article by Deyo, Cherkin, and Ciol (J Clin Epidemiol, 1992).] Select to access the abstract.

Medical Care Research and Review
Konetzka RT, Werner RM. Review: disparities in long-term care: building equity into market-based reforms. Med Care Res Rev 2009 Oct; 66(5):491-521. [Cites AHRQ-funded articles by Angelelli, Grabowski, and Mor (Am J Public Health, 2006), Cagney and Agree (J Gerontol B Psychol Sci Soc Sci, 1999), Cashen, Dykes, and Gerber (J Cardiovasc Nurs, 2004), and others.] Select to access the abstract.

Medical Decision Making
Lutfey KE, Link CL, Marceau LD, et al. Diagnostic certainty as a source of medical practice variation in coronary heart disease: results from a cross-national experiment of clinical decision making. Med Decis Making 2009 Sep-Oct; 29(5):606-18. [Cites AHRQ-funded articles by Ayanian and Epstein (N Engl J Med, 1991) and Bird et al. (Womens Health Issues, 2007).] Select to access the abstract.

New England Journal of Medicine
Okike K, Kocher MS, Wei EX, et al. Accuracy of conflict-of-interest disclosures reported by physicians. N Engl J Med 2009 Oct 8; 361(15):1466-74. [Cites AHRQ-funded article by Bell et al. (BMJ, 2006).] Select to access the abstract.

U.S. Preventive Services Task Force (USPSTF)/Put Prevention Into Practice (PPIP)-Related Articles

Annals of Family Medicine
Annals Journal Club. The 'yield' of targeted screening for type 2 diabetes. Ann Fam Med 2009 Sep-Oct; 7(5):iii. [Cites USPSTF summary of recommendations on screening for type 2 diabetes mellitus in adults, 2008, as published on AHRQ Web site; comments on article by Woolthuis et al. (Ann Fam Med, 2009) cited below.]

Woolthuis EP, de Grauw WJ, van Gerwen WH, et al. Yield of opportunistic targeted screening for type 2 diabetes in primary care: the Diabscreen study. Ann Fam Med 2009 Sep-Oct; 7(5):422-30. [Cites USPSTF recommendation statement and associated USPSTF-sponsored review of the evidence on screening adults for type 2 diabetes (Ann Intern Med, 2008).] Select to access the abstract.

Reuland DS, Cherrington A, Watkins GS, et al. Diagnostic accuracy of Spanish language depression-screening instruments. Ann Fam Med 2009 Sep-Oct; 7(5):455-62. [Cites USPSTF-sponsored summary of the evidence on screening for depression in adults (Ann Intern Med, 2002); cites USPSTF-sponsored systematic evidence review Screening for Depression, 2002, as published in U.S. Preventive Services Task Force Evidence Syntheses, formerly Systematic Evidence Reviews and posted on the NLM Web site as part of the Health Services/Technology Assessment Text (HSTAT) repository.] Select to access the abstract.

Annals of Internal Medicine
U.S. Preventive Services Task Force. Using nontraditional risk factors in coronary heart disease risk assessment: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 2009 Oct 6; 151(7):474-82. [Presents new USPSTF recommendations on the use of nontraditional risk factors in coronary heart disease risk assessment, based on USPSTF-sponsored systematic review and meta-analyses by Buckley et al. and Helfand et al. cited below.] Select to access the abstract.

Buckley DI, Fu R, Freeman M, et al. C-reactive protein as a risk factor for coronary heart disease: a systematic review and meta-analyses for the U.S. Preventive Services Task Force. Ann Intern Med 2009 Oct 6; 151(7):483-95. [Supported by contract 290-02-0024, task order 2, to the Oregon Evidence-based Practice Center.] Select to access the abstract.

Helfand M, Buckley DI, Freeman M, et al. Emerging risk factors for coronary heart disease: a summary of systematic reviews conducted for the U.S. Preventive Services Task Force. Ann Intern Med 2009 Oct 6; 151(7):496-507. [Supported by contract 290-02-0024, task order 2, to the Oregon Evidence-based Practice Center.] Select to access the abstract.

Summaries for Patients. Using nontraditional risk factors to estimate risk for coronary heart disease. Ann Intern Med 2009 Oct 6; 151(7):1-38. [Summarizes USPSTF recommendations on using nontraditional risk factors in coronary heart disease risk assessment (Ann Intern Med, 2009) as cited above.]

Medical Decision Making
Bentley TG, Weinstein MC, Kuntz KM. Effects of categorizing continuous variables in decision-analytic models. Med Decis Making 2009 Sep-Oct; 29(5):549-56. [Cites USPSTF-sponsored summary of the evidence on routine vitamin supplementation to prevent cardiovascular disease (Ann Intern Med, 2003).] Select to access the abstract.

Obstetrics and Gynecology
American College of Obstetricians and Gynecologists (ACOG) practice bulletin No. 109, Oct 2009: polycystic ovary syndrome. Obstet Gynecol 2009 Oct; 114(4):936-49. [Authors acknowledge that "studies were reviewed and evaluated for quality according to the method outlined by the [USPSTF]" .]

Social Science and Medicine
Gagnon AJ, Zimbeck M, Zeitlin J, et al. Migration to western industrialised countries and perinatal health: a systematic review. Soc Sci Med 2009 Sep; 69(6):934-46. [Uses USPSTF ratings criteria for cohort and case-control studies (Harris et al., Am J Prev Med, 2001) to assess the quality of selected studies and presents the applied criteria in Appendix B. Also go to the White Paper Series on Diagnostic Test Evaluation articles (Med Decis Making, 2009) cited in Evidence-based Practice Centers-Related Articles.] Select to access the abstract.

Evidence-based Practice Centers-Related Articles

Gerontologist
Arling G, Job C, Cooke V. Medicaid nursing home pay for performance: where do we stand? Gerontologist 2009 Oct; 49(5):587-95. [Cites AHRQ Evidence Report/Technology Assessment, Strategies to Support Quality-based Purchasing: A Review of the Evidence, 2004; cites several AHRQ-funded articles.] Select to access the abstract.

Medical Decision Making
Helfand M. Web exclusive white paper series on diagnostic test evaluation. Med Decis Making 2009 Sep-Oct; 29(5):634-5. [Introduces four papers (cited below), earlier versions of which were "presented May 28-29, 2008, in Rockville, Maryland, to an invited audience of investigators from the Evidence Based Practice Centers (EPCs) and other experts..." and noted that this meeting "marked the launch of a Diagnostic Test Evaluation Work Group, charged with developing guidance for conducting comparative effectiveness reviews of diagnostic technologies for the AHRQ Effective Health Care program."]

Lord SJ, Irwig L, Bossuyt PM. Using the principles of randomized controlled trial design to guide test evaluation. Med Decis Making 2009 (Online):1-12. [One of four papers from the AHRQ Effective Health Care Program White Paper Series on Diagnostic Test Evaluation; notes that the USPSTF analytic framework for screening tests provides valuable guidance for mapping out a causal pathway linking testing with patient outcomes... (Harris et al., Am J Prev Med, 2001).]

Lijmer JG, Leeflang M, Bossuyt PM. Proposals for a phased evaluation of medical tests. Med Decis Making 2009 (Online):1-9. [One of four papers from the AHRQ Effective Health Care Program White Paper Series on Diagnostic Test Evaluation; notes that the USPSTF "used to correlate its recommendations strongly with the research design of the most important studies, whereas nowadays it considers the evidence as a whole, using 8 steps in an analytical framework, a causal pathway linking screening or other preventive services to health outcomes" (Harris et al., Am J Prev Med, 2001).]

Trikalinos TA, Siebert U, Lau J. Decision-analytic modeling to evaluate benefits and harms of medical tests: uses and limitations. Med Decis Making 2009 (Online):1-12. [One of four papers from the AHRQ Effective Health Care Program White Paper Series on Diagnostic Test Evaluation, cites AHRQ Evidence Report/Technology Assessment, Evaluation of Technologies for Identifying Acute Cardiac Ischemia in Emergency Departments, 2001, and technology assessment Positron Emission Tomography, Single Photon Emission Computed Tomography, Functional Magnetic Resonance Imaging, and Magnetic Resonance Spectroscopy for the Diagnosis and Management of Alzheimer's Dementia, 2004; cites USPSTF-sponsored decision analysis on evaluating test strategies for colorectal cancer screening and recommendation on screening for colorectal cancer (Ann Intern Med, 2008).]

Bossuyt PM, McCaffery K. Additional patient outcomes and pathways in evaluations of testing. Med Decis Making 2009 (Online):1-12. [One of four papers from the AHRQ Effective Health Care Program White Paper Series on Diagnostic Test Evaluation.]

National Healthcare Quality Report (NHQR)/National Healthcare Disparities Report (NHDR)-Related Articles

Health Services Research
Palaniappan LP, Wong EC, Shin JJ, et al. Collecting patient race/ethnicity and primary language data in ambulatory care settings: a case study in methodology. Health Serv Res 2009 Oct; 44(5 Pt 1):1750-61. [Cites AHRQ's NHDR, 2007.] Select to access the abstract.

Medical Care Research and Review
Vargas Bustamante A, Fang H, Rizzo JA, et al. Understanding observed and unobserved health care access and utilization disparities among U.S. Latino adults. Med Care Res Rev 2009 Oct; 66(5):561-77. [Cites AHRQ's NHDR, 2007.] Select to access the abstract.

McHugh M, Kang R, Hasnain-Wynia R. Understanding the safety net: inpatient quality of care varies based on how one defines safety-net hospitals. Med Care Res Rev 2009 Oct; 66(5):590-605. [Cites AHRQ's NHDR, 2007; cites AHRQ publication, Serving the Uninsured: Safety Net Hospitals, 2003, HCUP Fact Book No. 8, 2007. Also refer to the articles by Cook and Manning (Health Serv Res, 2009) and Gaskin et al. (Med Care Res Rev, 2009) cited in Research by Others Using AHRQ Data or Products.] Select to access the abstract.

Research by Others Using AHRQ Data or Products

Health Services Research
Rosenthal MB, Li Z, Robertson AD, et al. Impact of financial incentives for prenatal care on birth outcomes and spending. Health Serv Res 2009 Oct; 44(5 Pt 1):1465-79. [Uses and cites Elixhauser comorbidity measures (Elixhauser et al., Med Care, 1998); cites AHRQ-funded articles by Landon et al. (Am J Manage Care, 2008) and Rosenthal et al. (N Engl J Med, 2006).] Select to access the abstract.

Singer SJ, Hartmann CW, Hanchate A, et al. Comparing safety climate between two populations of hospitals in the United States. Health Serv Res 2009 Oct; 44(5 Pt 1):1563-83. [Uses and cites AHRQ's patient safety indicators; cites AHRQ publications, Advances in Patient Safety: From Research to Implementation, Vol. 1, 2005, and Hospital Survey on Patient Safety Culture: 2007 Comparative Database Report, 2009.] Select to access the abstract.

Cook BL, Manning WG. Measuring racial/ethnic disparities across the distribution of health care expenditures. Health Serv Res 2009 Oct; 44(5 Pt 1):1603-21. [Uses 2001-2005 MEPS data; cites AHRQ's NHDR, 2007.] Select to access the abstract.

West AN, Weeks WB. Health care expenditures for urban and rural veterans in Veterans Health Administration care. Health Serv Res 2009 Oct; 44(5 Pt 1):1718-34. [Uses and cites 1996-2004 MEPS data; cites AHRQ publication, Overview of Methodology for Imputing Missing Expenditure Data in the Medical Expenditure Panel Survey, 2004, as published on AHRQ Web site.] Select to access the abstract.

Medical Care Research and Review
Gaskin DJ, Price A, Brandon DT, et al. Segregation and disparities in health services use. Med Care Res Rev 2009 Oct; 66(5):578-89. [Uses 2002 MEPS data; uses and cites AHRQ's NHDR, 2006.] Select to access the abstract.

Medicine
Farkouh ME, Aneja A, Reeder GS, et al. Clinical risk stratification in the emergency department predicts long-term cardiovascular outcomes in a population-based cohort presenting with acute chest pain: primary results of the Olmsted county chest pain study. Medicine 2009 Sep; 88(5):307-13. [Describes and validates the diagnostic model presented in the AHRQ-sponsored guideline, Unstable Angina Diagnosis and Management, 1994 (archived); cites article by Brotons et al. (J Clin Epidemiol, 1999), which uses AHRQ's classification for managing unstable angina.] Select to access the abstract.