Patient-centered Medical Home Cost Reductions Limited to Complex Patients

November 23, 2012

This weekly compilation of articles appearing in recently released journals and newsletters includes:

• Articles funded by the Agency for Healthcare Research and Quality (AHRQ) or authored by AHRQ researchers.
• Articles mentioning or discussing AHRQ staff, activities, and publications/products.
• Articles related to AHRQ-funded Evidence-based Practice Centers.
• Articles related to the U.S. Preventive Services Task Force or Put Prevention into Practice program.
• Articles mentioning the National Healthcare Disparities Report and National Healthcare Quality Report.
• Other research using AHRQ data or products.

AHRQ-Funded/Authored Articles

American Journal of Managed Care
Flottemesch TJ, Anderson LH, Lolberg LI, et al. Patient-centered medical home cost reductions limited to complex patients. Am J Manag Care 2012 Nov; 18(11):677-86. [Supported by contract HHSA 290-2007-10010.]

Chang HY, Weiner JP, Richards TM, et al. Validating the adapted Diabetes Complications Severity Index in claims data. Am J Manag Care 2012 Nov; 18(11):721-6. [Supported by AHRQ, no funding information given.]

Haas JS, Klinger E, Marinacci LX, et al. Active pharmacovigilance and healthcare utilization. Am J Manag Care 2012 Nov; 18(11):e423-e428. [Supported by grant U18 HS16970.]

American Journal of Medical Quality
Sarfaty M, Myers RE, Harris DM, et al. Variation in colorectal cancer screening steps in primary care: basis for practice improvement. Am J Med Qual 2012 Nov-Dec; 27(6):458-66. [Supported by contract HHSA 290-2006-00014, task order 1 as part of AHRQ's Accelerating Change and Transformation in Organizations and Networks (ACTION) program; based on research described in AHRQ publications, Toolkit for the System Approach to Tracking and Increasing Screening for Public Health Improvement of Colorectal Cancer (SATIS-PHI/CRC) Intervention and Health Care Systems for Tracking Colorectal Cancer Screening Tests: Final Report on the System Approach to Tracking and Increasing Screening for Public Health Improvement of Colorectal Cancer (SATIS-PHI/CRC) Intervention, both published on the AHRQ Web site.] Select to access the abstract.

Yu H, Greenberg MD, Haviland AM, et al. Multiple patient safety events within a single hospitalization: a national profile in US hospitals. Am J Med Qual 2012 Nov-Dec; 27(6):472-9. [Supported by contract 290-02-0010; uses 1997 and 2004 HCUP NIS data, citing Introduction to the HCUP Nationwide Inpatient Sample (NIS), 2002, 2004, and Introduction to the HCUP Nationwide Inpatient Sample (NIS), 2007, both published on AHRQ's HCUP Web site, and uses "AHRQ's recommendations for using the NIS Trends Supplemental files to ensure that the NIS data files from different years had consistently defined data elements and national weights"; also uses AHRQ Patient Safety Indicators, citing AHRQ Quality Indicators: Guide to Patient Safety Indicators, Version 3.1, 2007, and AHRQ Quality Indicators—Patient Safety Indicators: Software Documentation, Version 2.1— SAS, 2003.] Select to access the abstract.

Wakefield DS, Kruse RL, Wakefield BJ, et al. Consistency of patient preferences about a secure Internet-based patient communications portal: contemplating, enrolling, and using. Am J Med Qual 2012 Nov-Dec; 27(6):494-502. [Supported by grant R18 HS17035.] Select to access the abstract.

Albrecht JS, Hirshon JM, Goldberg R, et al. Serious mental illness and acute hospital readmission in diabetic patients. Am J Med Qual 2012 Nov-Dec; 27(6):503-8. [Supported by grants R36 HS21068-01 (to first author) and K08 HS18111-01 (to sixth author).] Select to access the abstract.

Inquiry
Friedman B, Jiang HJ, Steiner CA, et al. Likelihood of hospital readmission after first discharge: Medicare Advantage vs. fee-for-service patients. Inquiry 2012 Fall; 49(3):202-13. [Authors are researchers in AHRQ's Center for Delivery, Organization, and Markets; uses 2006 Healthcare Cost and Utilization Project (HCUP) State Inpatient Databases (SID) for Arizona, California, Florida, Massachusetts, and Tennessee (citing HCUP Web site publication, SID Database Documentation), HCUP Clinical Classifications Software (CCS) (citing HCUP Web site publication, Clinical Classifications Software (CCS) for ICD-9-CM), procedures for categorizing hospital stays described on AHRQ's HCUP Web site, AHRQ's Elixhauser comorbidity measures (Elixhauser et al., Med Care, 1998), AHRQ's HCUP Comorbidity Software, Version 3.7 (as published on AHRQ's HCUP Web site), and AHRQ's Quality Indicators; cites AHRQ publication, Medicare Hospital Stays: Comparisons between the Fee-for-Service Plan and Alternative Plans, 2006, HCUP Statistical Brief 66, 2009, as published on AHRQ's HCUP Web site.]

Shoemaker JS, Davidoff AJ, Stuart B, et al. Eligibility and take-up of the Medicare Part D low-income subsidy. Inquiry 2012 Fall; 49(3):214-30. [Supported by grant R36 HS20866. Also refer to AHRQ-funded articles by Chou et al. (Ann Intern Med, 2012) cited in U.S. Preventive Services Task Force (USPSTF)/Put Prevention Into Practice (PPIP)-Related Articles.]

AHRQ-Related Articles

American Journal of Managed Care
Wu C, Chen R, Tsai H, et al. How comorbidities and preoperative expenditures correlate with postoperative adverse outcomes. Am J Manag Care 2012 Nov; 18(11):e405-e415. [Cites AHRQ-authored article by Eisenberg and Power (former AHRQ director and AHRQ researcher, respectively) (JAMA, 2000); cites AHRQ-funded articles by Ghaferi, Birkmeyer, and Dimick (N Engl J Med, 2009), Likosky et al. (Circulation, 2009), Leff et al. (Am J Manag Care, 2009), and Polanczyk et al. (Ann Intern Med, 2001); cites article by Bateman et al. (Neurosurgery, 2005), which uses 1998-2002 HCUP Nationwide Inpatient Sample (NIS) data.]

American Journal of Medical Quality
Kane JM, Fusilero LS, Joy BF, et al. Establishing quality review of cardiac and respiratory arrest in a pediatric intensive care unit. Am J Med Qual 2012 Nov-Dec; 27(6):509-17. [Cites AHRQ publication, Advances in Patient Safety: New Directions and Alternative Approaches, Volume 2, 2008.] Select to access the abstract.

Annals of Internal Medicine
Qaseem A, Fihn SD, Williams S, et al. Diagnosis of stable ischemic heart disease: summary of a clinical practice guideline from the American College of Physicians/American College of Cardiology Foundation/American Heart Association/ American Association for Thoracic Surgery/Preventive Cardiovascular Nurses Association/Society of Thoracic Surgeons. Ann Intern Med 2012 Nov 20; 157(10):729-34. [Cites AHRQ-sponsored guideline, Unstable Angina: Diagnosis and Management, 1994; cites AHRQ-funded articles by Morise and Diamond (Am Heart J, 1995) and Pryor et al. (Ann Intern Med, 1993, and Am J Med, 1991), Mark et al. (N Engl J Med, 1991, and Ann Intern Med, 1987), and others.] Select to access the abstract.

Archives of Surgery
Hervey-Jumper SL, Maher CO. Is insurance status a modifiable factor in brain tumor treatment outcomes? Arch Surg 2012 Nov; 147(11):1025. [Comments on article by Momin et al. (Arch Surg, 2012) cited in Research by Others Using AHRQ Data or Products.]

Cisco RM, Kuo JH, Ogawa L, et al. Impact of race on intraoperative parathyroid hormone kinetics: an analysis of 910 patients undergoing parathyroidectomy for primary hyperparathyroidism. Arch Surg 2012 Nov; 147(11):1036-40. [Cites AHRQ-authored article by Zuvekas and Taliaferro (current researcher in AHRQ's Center for Financing, Access, and Cost Trends and former AHRQ researcher, respectively) (Health Aff, 2003).] Select to access the abstract.

Family Medicine
Carek PJ, Peterson L, Shokar NK, et al. Graduate medical education and primary care workforce: a CERA study. Fam Med 2012 Nov-Dec; 44(10):712-15. [Cites AHRQ-funded articles by Macinko, Starfield, and Shi (Health Serv Res, 2003) and Grumbach et al. (JAMA, 1999).] Select to access the abstract.

Carlston DL, Mattar AA, Packard J. Exploratory analysis of patients' motivations to quit smoking and participate in smoking cessation classes. Fam Med 2012 Nov-Dec; 44(10):727-30. [Cites AHRQ-sponsored guideline, Treating Tobacco Use and Dependence: 2008 Update, 2008, as published on the National Library of Medicine NCBI Bookshelf Web site; cites National Committee for Quality Assurance (NCQA) measure summary "Smoking and tobacco use cessation: percentage of members 18 years of age and older who were current smokers or tobacco users and who discussed or were recommended cessation medications during the measurement year," 2010, as published on AHRQ's National Quality Measures Clearinghouse; cites article by Moran et al. (Nicotine Tob Res, 2003), which uses AHRQ-sponsored guideline, Treating Tobacco Use and Dependence, 2000.] Select to access the abstract.

JAMA
Bates DW, Wells S. Personal health records and health care utilization. JAMA 2012 Nov 21; 308(19):2034-6. [Cites AHRQ publication, Advances in Patient Safety: New Directions and Alternative Approaches, Volume 4: Technology and Medication Safety, 2008; cites AHRQ-funded article by Hassol et al. (J Am Inform Assoc, 2004).]

Lancet
Lopes RD, Al-Khatib SM, Wallentin L, et al. Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial. Lancet 2012 Nov 17; 380(9855):1749-58. [Cites AHRQ-funded articles by Piccini et al. (J Am Coll Cardiol, 2009) and Gage et al. (JAMA, 2001).] Select to access the abstract.

Maternal and Child Health Journal
Bromley E, Nunes A, Phipps MG. Disparities in pregnancy healthcare utilization between Hispanic and non-Hispanic white women in Rhode Island. Matern Child Health J 2012 Nov; 16(8):1576-82. [Cites AHRQ-authored article by Weinick, Jacobs, Stone, Ortega, and Burstin (first and fifth authors are former AHRQ researchers) (Med Care, 2004).] Select to access the abstract.

Mayo Clinic Proceedings
Safdar N. Clostridium difficile: the emerging epidemic. Mayo Clin Proc 2012 Nov; 87(11):1037-9. [Comments on article by Khanna and Pardi, cited below in this section, and article by Keddis et al. (Mayo Clin Proc, 2012) cited in Research by Others Using AHRQ Data or Products.]

Grimsby GM, Conley SP, Trentman TL, et al. A double-blind randomized controlled trial of continuous intravenous ketorolac vs placebo for adjuvant pain control after renal surgery. Mayo Clin Proc 2012 Nov; 87(11):1089-97. [Cites AHRQ-sponsored guideline, Acute Pain Management: Operative or Medical Procedures and Trauma, 1992.] Select to access the abstract.

Khanna S, Pardi DS. Clostridium difficile infection: new insights into management. Mayo Clin Proc 2012 Nov; 87(11):1106-17. [Mentions AHRQ's HCUP Nationwide Inpatient Sample (NIS) as a primary source of derived epidemiologic data for clostridium difficile infection, citing articles by Ricciardi R et al. (Arch Surg, 2007), and Zilberberg et al. (Pediatr Infect Dis J, 2008, and Emerg Infect Dis, 2008); cites article by Ananthakrishnan, McGinley, and Binion (Gut, 2008), which uses 2003 HCUP NIS data.] Select to access the abstract.

New England Journal of Medicine
Rosenbaum L, Lamas D. Residents' duty hours— toward an empirical narrative. N Engl J Med 2012 Nov 22; 367(21):2044-9. [Cites AHRQ-funded articles by Lockley et al (N Engl J Med, 2004) and Landrigan et al. (N Engl J Med, 2004).]

U.S. Preventive Services Task Force (USPSTF)/Put Prevention Into Practice (PPIP)-Related Articles

American Journal of Managed Care
Smith DH, Feldstein AC, Perrin N, et al. Automated telephone calls to enhance colorectal cancer screening: economic analysis. Am J Manag Care 2012 Nov; 18(11):691-9. [Selects study participants on the basis of USPSTF recommendations on colorectal cancer screening in place at the time of the study's trial initiation, citing USPSTF-sponsored updated, targeted systematic review on screening for colorectal cancer (Ann Intern Med, 2008).]

American Journal of Obstetrics and Gynecology
Miller KL, Baraldi CA. Geriatric gynecology: promoting health and avoiding harm. Am J Obstet Gynecol 2012 Nov; 207(5):355-67. [Cites USPSTF recommendation statements, Screening for Cervical Cancer, 2012, Screening for Breast Cancer, 2009, and Screening for Colorectal Cancer, 2008, all published on the USPSTF Web site; cites AHRQ Evidence Report/Technology Assessment, Prevention of Urinary and Fecal Incontinence in Adults, 2007.] Select to access the abstract.

Annals of Internal Medicine
Chou R, Selph S, Dana T, et al. Screening for HIV: systematic review to update the 2005 U.S. Preventive Services Task Force recommendation. Ann Intern Med 2012 Nov 20; 157(10):706-18. [Supported by contract HHSA 290-2007-10057-I, task order 8, and based on USPSTF evidence synthesis, Screening for HIV: Systematic Review to Update the 2005 U.S. Preventive Services Task Force Recommendation, 2012, as published on the USPSTF Web site; updates USPSTF recommendation statement, Screening for HIV, 2007, as published on the USPSTF Web site, and associated USPSTF-sponsored evidence review on screening for HIV (Ann Intern Med, 2005), USPSTF evidence synthesis, Screening for Human Immunodeficiency Virus in Adolescents and Adults, 2005, and USPSTF evidence syntheses, Screening for Human Immunodeficiency Virus: Focused Update of a 2005 Systematic Evidence Review for the U.S. Preventive Services Task Force, 2007, as published on the USPSTF Web site; rates quality of evidence of selected studies using methodologies in USPSTF-sponsored article by Harris et al. (Am J Prev Med, 2001); acknowledges support by Jennifer Croswell, researcher in AHRQ's Center for Primary Care, Prevention, and Clinical Partnerships.] Select to access the abstract.

Chou R, Cantor AG, Zakher B, et al. Screening for HIV in pregnant women: systematic review to update the 2005 U.S. Preventive Services Task Force recommendation. Ann Intern Med 2012 Nov 20; 157(10):719-28. [Supported in part by contract 290-02-0024 and based on USPSTF evidence synthesis, Screening for HIV in Pregnant Women: Systematic Review to Update the 2005 U.S. Preventive Services Task Force Recommendation, 2012, as published on the USPSTF Web site; updates USPSTF recommendation statement, Screening for HIV, 2007, as published on the USPSTF Web site, and associated USPSTF-sponsored evidence review on prenatal screening for HIV (Ann Intern Med, 2005) and USPSTF evidence synthesis, Screening for Human Immunodeficiency Virus in Pregnant Women, 2005, as published on the USPSTF Web site; rates quality of evidence of selected studies using methodologies in USPSTF-sponsored article by Harris et al. (Am J Prev Med, 2001); acknowledges support by Jennifer Croswell, researcher in AHRQ's Center for Primary Care, Prevention, and Clinical Partnerships.] Select to access the abstract.

Lancet
Engelgau MM, Gregg EW. Tackling the global diabetes burden: will screening help? Lancet 2012 Nov 17; 380(9855):1716-18. [Cites USPSTF-sponsored evidence review on screening for type 2 diabetes (Ann Intern Med, 2008).]

Independent UK Panel on Breast Cancer Screening. The benefits and harms of breast cancer screening: an independent review. Lancet 2012 Nov 17; 380(9855):1778-86. [Includes updated 2009 USPSTF recommendations on screening for breast cancer in review, citing USPSTF-sponsored evidence update on screening for breast cancer (Ann Intern Med, 2009) and related article by Woolf (JAMA, 2010), which comments on these USPSTF recommendations.] Select to access the abstract.

Maternal and Child Health Journal
Harrison PA, Godecker A, Sidebottom AC. Validation of the alcohol use module from a multidimensional prenatal psychosocial risk screening instrument. Matern Child Health J 2012 Dec; 16(9):1791-1800. [Cites USPSTF recommendations on screening for prenatal alcohol use in health care settings in Guide to Clinical Preventive Services, 2010-2011.] Select to access the abstract.

Williams L, Zapata LB, D'Angelo DV, et al. Associations between preconception counseling and maternal behaviors before and during pregnancy. Matern Child Health J 2012 Dec; 16(9):1854-61. [Cites USPSTF evidence synthesis, Behavioral Counseling Interventions in Primary Care to Reduce Risky/Harmful Alcohol Use, 2004; cites AHRQ Evidence Report/Technology Assessment, Tobacco Use: Prevention, Cessation, and Control, 2006; cites AHRQ-sponsored guideline, Treating Tobacco Use and Dependence: 2008 Update, 2008; cites article by Goldstein et al. (Am J Prev Med, 2004), which uses USPSTF guidelines and AHRQ-sponsored guideline, Treating Tobacco Use and Dependence, 2000.] Select to access the abstract.

Evidence-based Practice Centers-Related Articles

American Journal of Managed Care
Lee JL, Fischer MA, Shrank WH, et al. A systematic review of reference pricing: implications for US prescription drug spending. Am J Manag Care 2012 Nov; 18(11):e429-e437. [Uses AHRQ Evidence Report/Technology Assessment, Systems to Rate the Strength of Scientific Evidence, 2002, to assess study quality; cites AHRQ-funded articles by Schneeweiss et al. (Circulation, 2007, Clin Pharmacol Ther, 2003, Med Care, 2004, and N Engl J Med, 2002), and others.]

Annals of Internal Medicine
Spitzer M, Basaria S, Travison TG, et al. Effect of testosterone replacement on response to sildenafil citrate in men with erectile dysfunction: a parallel, randomized trial. Ann Intern Med 2012 Nov 20; 157(10):681-91. [Discusses findings from AHRQ-funded systematic review and evidence update on hormonal treatments for erectile dysfunction by Tsertsvadze et al. (Ann Intern Med, 2009), prepared by the Minneapolis Evidence-based Practice Center (EPC) under contract 290-02-0021, and article by Qaseem et al. (Ann Intern Med, 2009), which is based on that AHRQ review.] Select to access the abstract.

Shorr RI, Chandler AM, Mion LC, et al. Effects of an intervention to increase bed alarm use to prevent falls in hospitalized patients: a cluster randomized trial. Ann Intern Med 2012 Nov 20; 157(10):692-9. [Cites "Chapter 26. Prevention of Falls in Hospitalized and Institutionalized Older People" in AHRQ Evidence Report/Technology Assessment, Making Health Care Safer: A Critical Analysis of Patient Safety Practices, 2001.] Select to access the abstract.

Allen AS, Sequist TD. Pharmacy dispensing of electronically discontinued medications. Ann Intern Med 2012 Nov 20; 157(10):700-5. [Cites AHRQ-funded systematic review by Chaudhry et al. (Ann Intern Med, 2006) on the impact of health information technology on quality, efficiency, and costs of medical care, prepared by the Southern California-University of California at San Francisco EPC; cites AHRQ-funded articles by Kaushal et al. (J Gen Intern Med, 2012) and others.] Select to access the abstract.

Archives of Surgery
Feuerbacher RL, Funk KH, Spight DH, et al. Realistic distractions and interruptions that impair simulated surgical performance by novice surgeons. Arch Surg 2012 Nov; 147(11):1026-30. [Cites AHRQ Evidence Report/Technology Assessment, The Effect of Health Care Working Conditions on Patient Safety, 2003, as published on the AHRQ Archive Web site.] Select to access the abstract.

Drug Topics
Nigro SC, Salvo MC. Oral antidiabetes agents and noninsulin injectables for diabetes care. Drug Topics 2012 Nov 1; 156(11):40-50. [Cites AHRQ comparative effectiveness review, Comparative Effectiveness and Safety of Oral Diabetes Medications for Adults with Type 2 Diabetes, 2007.]

Maternal and Child Health Journal
Ahluwalia IB, Morrow B, D'Angelo D, et al. Maternity care practices and breastfeeding experiences of women in different racial and ethnic groups: Pregnancy Risk Assessment and Monitoring System (PRAMS). Matern Child Health J 2012 Nov; 16(8):1672-8. [Cites AHRQ Evidence Report/Technology Assessment, Breastfeeding and Maternal and Infant Health Outcomes in Developed Countries, 2007.] Select to access the abstract.

Langellier BA, Pia Chaparro M, Whaley SE. Social and institutional factors that affect breastfeeding duration Among WIC participants in Los Angeles County, California. Matern Child Health J 2012 Dec; 16(9):1887-95. [Cites AHRQ Evidence Report/Technology Assessment, Breastfeeding and Maternal and Infant Health Outcomes in Developed Countries, 2007. Also refer to articles by Miller et al. (Am J Obstet Gynecol, 2012) and Williams et al. (Matern Child Health J, 2012) cited in U.S. Preventive Services Task Force (USPSTF)/Put Prevention Into Practice (PPIP)-Related Articles, and article by Lee et al. (Am J Manag Care, 2012) cited in Research by Others Using AHRQ Data or Products.] Select to access the abstract.

National Healthcare Quality Report (NHQR)/National Healthcare Disparities Report (NHDR)-Related Articles

JAMA
Armstrong K. Genomics and health care disparities: the role of statistical discrimination. JAMA 2012 Nov 21; 308(19):1979-80. [Cites AHRQ's NHQR/NHDR, 2010.]

Research by Others Using AHRQ Data or Products

American Journal of Managed Care
Goddard KA, Bowles EJ, Feigelson HS, et al. Utilization of HER2 genetic testing in a multi-institutional observational study. Am J Manag Care 2012 Nov; 18(11):704-12. [Uses the AHRQ-funded adaptation of the Charlson comorbidity index described in AHRQ-funded article by Deyo, Cherkin, and Ciol (J Clin Epidemiol, 1992).]

Archives of Surgery
Momin EN, Adams H, Shinohara RT, et al. Postoperative mortality after surgery for brain tumors by patient insurance status in the United States. Arch Surg 2012 Nov; 147(11):1017-24. [Uses 1999-2008 HCUP NIS data, citing AHRQ publication, Comorbidity Software Documentation, HCUP Method Series Report 2004-1, 2004, as published on AHRQ's HCUP Web site, and classifies the variable "admission type" according to AHRQ criteria; also uses AHRQ's Elixhauser comorbidity measures (Elixhauser et al., Med Care, 1998), noting its possible superiority "to the Charlson/Deyo method when administrative databases are used to study surgical populations," citing the AHRQ-funded adaptation of the Charlson comorbidity index described in AHRQ-funded article by Deyo, Cherkin, and Ciol (J Clin Epidemiol, 1992); cites AHRQ-authored articles by Steiner, Elixhauser, and Schnaier (researchers in AHRQ's Center for Delivery, Organization, and Markets) (Eff Clin Pract, 2002, which uses various HCUP data sets) and Franks, Clancy (AHRQ director), and Gold (JAMA, 1993).]

Mayo Clinic Proceedings
Keddis MT, Khanna S, Noheria A, et al. Clostridium difficile infection in patients with chronic kidney disease. Mayo Clin Proc 2012 Nov; 87(11):1046-53. [Uses HCUP Comorbidity Software to collect various comorbid conditions from the utilized database, citing Comorbidity Software, Version 3.7, as published on AHRQ's HCUP Web site. Also refer to articles by Yu et al. (Am J Med Qual, 2012) and Friedman et al. (Inquiry, 2012) cited in AHRQ-Funded/ Authored Articles.] Select to access the abstract.