122. Treatment Recommendations: Medications (Continued)

Treating Tobacco Use and Dependence: 2008 Update

Text version of slide presentation.

Treatment Recommendations: Medications (Continued)

Meta-analysis (2008): Effectiveness and abstinence rates for various medications and medication combinations compared to placebo at 6-months post-quit (n = 86 studies)

MedicationNumber of armsEstimated odds ratio (95% C.I.)Estimated abstinence rate (95% C.I.)
Placebo801.013.8
Monotherapies   
Bupropion SR262.0 (1.8, 2.2)24.2 (22.2, 26.4)
Nicotine Patch (6-14 weeks)321.9 (1.7, 2.2)23.4 (21.3, 25.8)
Long-Term Nicotine Patch (> 14 weeks)101.9 (1.7, 2.3)23.7 (21.0, 26.6)
Nortriptyline51.8 (1.3, 2.6)22.5 (16.8, 29.4)
Nicotine Gum (6-14 weeks)151.5 (1.2, 1.7)19.0 (16.5, 21.9)

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Page last reviewed June 2009
Internet Citation: 122. Treatment Recommendations: Medications (Continued): Treating Tobacco Use and Dependence: 2008 Update. June 2009. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/professionals/clinicians-providers/guidelines-recommendations/tobacco/clinicians/presentations/2008update-full/slide122.html