157. Treatment Recommendations: Medications-Relative Effectiveness

Treating Tobacco Use and Dependence: 2008 Update
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Medication Number of arms Estimated odds ratio (95% C. I.)

Medication Number of arms Estimated odds ratio (95% C. I.)
Nicotine Patch (reference group) 32 1.0
Monotherapies    
Varenicline (2 mg/day) 5 1.6 (1.3, 2.0)
Nicotine Nasal Spray 4 1.2 (0.9, 1.6)
High Dose Nicotine Patch ( > 25 mg; standard or long-term) 4 1.2 (0.9, 1.6)
Long-Term Nicotine Gum (> 14 weeks) 6 1.2 (0.8, 1.7)
Varenicline (1 mg/day) 3 1.1 (0.8, 1.6)
Nicotine Inhaler 6 1.1 (0.8, 1.5)

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Page last reviewed October 2014
Internet Citation: 157. Treatment Recommendations: Medications-Relative Effectiveness. October 2014. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/professionals/clinicians-providers/guidelines-recommendations/tobacco/clinicians/presentations/2008update-full/slide157.html