158. Treatment Recommendations: Medications-Relative Effectiveness (Continued)

Treating Tobacco Use and Dependence: 2008 Update
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Meta-analysis (2008): Effectiveness and abstinence rates of medications relative to the nicotine patch (n = 86 studies).

Medication Number of arms Estimated odds ratio (95% C. I.)
Nicotine Patch (reference group) 32 1.0
Monotherapies    
Clonidine 3 1.1 (0.6, 2.0)
Bupropion SR 26 1.0 (0.9, 1.2)
Long-Term Nicotine Patch (> 14 weeks) 10 1.0 (0.9, 1.2)
Nortriptyline 5 0.9 (0.6, 1.4)
Nicotine Gum 15 0.8 (0.6, 1.0)

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Page last reviewed October 2014
Internet Citation: 158. Treatment Recommendations: Medications-Relative Effectiveness (Continued). October 2014. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/professionals/clinicians-providers/guidelines-recommendations/tobacco/clinicians/presentations/2008update-full/slide158.html