20. Varenicline

Treating Tobacco Use and Dependence: 2008 Update Overview
Text version of slide presentation.

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Effectiveness and abstinence rates for various medications and medication combinations compared to placebo at 6-months post-quit (n = 86 studies).

Medication Number of arms Estimated odds ratio (95% C.I.) Estimated abstinence rate (95% C.I.)
Placebo 80 1.0 13.8
Varenicline
(2 mg/day)
5 3.1
(2.5, 3.8)
33.2
(28.9, 37.8)

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Page last reviewed October 2014
Internet Citation: 20. Varenicline. October 2014. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/professionals/clinicians-providers/guidelines-recommendations/tobacco/clinicians/presentations/2008update-overview/slide20.html