AHRQ Multiple Chronic Conditions Research Network Publications

This bibliography includes publications resulting from R18, R21 and R24 AHRQ Multiple Chronic Conditions Research Network grants funded between 2008 and 2010. The publications listed below are those that were published or in press as of August 2013.
  1. Alsheikh-Ali AA, Trikalinos TA, Ruthazer R, et al. Risk of arrhythmic and nonarrhythmic death in patients with heart failure and chronic kidney disease. Am Heart J. Jan 2011;161(1):204–209. e1.
  2. Bayliss EA, Blatchford PJ, Newcomer SR, et al. The effect of incident cancer, depression and pulmonary disease exacerbations on type 2 diabetes control. J Gen Intern Med. Jun 2011;26(6):575–581.
  3. Bayliss EA, Bronsert MR, Reifler LM, et al. Statin prescribing patterns in a cohort of cancer patients with poor prognosis. J Palliat Med. Apr 2013;16(4):412–418.
  4. Belmin J, Min L, Roth C, et al. Assessment and management of patients with cognitive impairment and dementia in primary care. J Nutr Health Aging. May 2012;16(5):462–467.
  5. Bird ST, Hartzema AG, Brophy JM, et al. Risk of venous thromboembolism in women with polycystic ovary syndrome: a population-based matched cohort analysis. CMAJ. Feb 5 2013;185(2):E115–120.
  6. Blum S, Vardi M, Brown JB, et al. Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype. Pharmacogenomics. May 2010;11(5):675–684.
  7. Boyd CM, Kent DM. Evidence-based medicine and the hard problem of multimorbidity. J Gen Intern Med. January 2014:1-2.
  8. Boyd CM, Vollenweider D, Puhan MA. Informing evidence-based decision-making for patients with comorbidity: availability of necessary information in clinical trials for chronic diseases. PLoS One. 2012;7(8):e41601.
  9. Boyd CM, Wolff JL, Giovannetti E, et al. Health care task difficulty among older adults with multimorbidity. Med Care. Mar 2014; 52(Suppl. 3):S118-125.
  10. Brooks JM, Cook EA, Chapman CG, et al. Geographic variation in statin use for complex acute myocardial infarction patients: evidence of effective care? Med Care. Mar 2014; 52(Suppl. 3):S37-44.
  11. Brown JM, Stewart JC, Stump TE, et al. Risk of coronary heart disease events over 15 years among older adults with depressive symptoms. Am J Geriatr Psychiatry. Aug 2011;19(8):721–729.
  12. Buzkova P. Measurement error and outcomes defined by exceeding a threshold: biased findings in comparative effectiveness trials. Pharm Stat. Nov–Dec 2012;11(6):429–441.
  13. Chrischilles E, Schneider K, Wilwert J, et al. Beyond comorbidity: Expanding the definition and measurement of complexity among older adults using administrative claims data. Med Care. Mar 2014;52(Suppl. 3):S75-84.
  14. Cigolle CT, Kabeto MU, Lee PG, et al. Clinical complexity and mortality in middle-aged and older adults with diabetes. J Gerontol A Biol Sci Med Sci. Dec 2012;67(12):1313–1320.
  15. Crane HM, Grunfeld C, Willig JH, et al. Impact of NRTIs on lipid levels among a large HIV-infected cohort initiating antiretroviral therapy in clinical care. AIDS. Jan 14 2011;25(2):185–195.
  16. DeLia D. Leaving it to chance: the effects of random variation in shared savings arrangements. Health Serv Outcomes Res Method.2013;13:219 - 240.
  17. DeLia D, Cantor J. Proposed approach for calculating savings in the NJ Medicaid ACO demonstration project. 2012. Available at: http://www.cshp.rutgers.edu/Downloads/9290.pdf. Accessed August 31, 2013.
  18. DeLia D, Hoover D, Cantor J. Statistical uncertainty in the Medicare program. Medicare and Medicaid Research Review. 2012;2(4):e1–16.
  19. Denton BT, Kurt M, Shah ND, et al. Optimizing the start time of statin therapy for patients with diabetes. Med Decis Making. May–Jun 2009;29(3):351–367.
  20. Domino M, Beadles CA, Lichstein JC, et al. Heterogeneity in the quality of care for patients with multiple chronic conditions by psychiatric comorbidity. Med Care. Mar 2014;52(Suppl. 3):S101-109.
  21. Druss BG, Zhao L, Cummings JR, et al. Mental comorbidity and quality of diabetes care under Medicaid: a 50-state analysis. Med Care. May 2012;50(5):428–433.
  22. Fischer HH, Moore SL, Ginosar D, et al. Care by cell phone: text messaging for chronic disease management. Am J Manag Care. Feb 2012;18(2):e42–47.
  23. Freeman E, Thomas JW, Thayer DA, et al. Factors affecting costs in Medicaid populations with behavioral health disorders. Med Care. Mar 2014;52(Suppl. 3):S60-66.
  24. Gancayco J, Soulos PR, Khiani V, et al. Age-based and sex-based disparities in screening colonoscopy use among medicare beneficiaries. J Clin Gastroenterol. Aug 2013;47(7):630–636.
  25. Gibson G, Jurasic MM, Wehler CJ, et al. Supplemental fluoride use for moderate and high caries risk adults: a systematic review. J Public Health Dent. Summer 2011;71(3):171–184.
  26. Giovannetti ER, Wolff JL, Xue QL, et al. Difficulty assisting with health care tasks among caregivers of multimorbid older adults. J Gen Intern Med. Jan 2012;27(1):37–44.
  27. Grembowski DE, Schaefer J, Johnson K, et al. The AHRQ Multiple Chronic Conditions Research Network conceptual model for research on complex patient care. Med Care. Mar 2014;52(Suppl. 3):S7-14.
  28. Gross CP, Soulos PR, Ross JS, et al. Assessing the impact of screening colonoscopy on mortality in the medicare population. J Gen Intern Med. Dec 2011;26(12):1441–1449.
  29. Han JH, Crane HM, Bellamy SL, et al. HIV infection and glycemic response to newly initiated diabetic medical therapy. AIDS. Oct 23 2012;26(16):2087–2095.
  30. Hansen R, Powers B, Sanders L, et al. Medication adherence and prescriber continuity for complex patients. In Press, Annals of Pharmacotherapy.
  31. Hempstead K, DeLia D, Cantor J, et al. The fragmentation of hospital use among a cohort of high utilizers: implications for emerging care coordination strategies for patients with multiple chronic conditions. Med Care. Mar 2014;52(Suppl. 3):S67-74
  32. Hernandez MN, Voti L, Feldman JD, et al. Cancer registry enrichment via linkage with hospital-based electronic medical records: a pilot investigation. J Registry Manag. Spring 2013;40(1):40–47.
  33. Jordan N, Sohn M-W, Bartle B, et al. Association between chronic illness complexity and receipt of evidence-based depression care. Med Care. Mar 2014; 52(Suppl. 3):S126-131.
  34. Khiani VS, Soulos P, Gancayco J, et al. Anesthesiologist involvement in screening colonoscopy: temporal trends and cost implications in the medicare population. Clin Gastroenterol Hepatol. Jan 2012;10(1):58–64 e51.
  35. Kim DJ, Westfall AO, Chamot E, et al. Multimorbidity patterns in HIV-infected patients: the role of obesity in chronic disease clustering. J Acquir Immune Defic Syndr. Dec 15 2012;61(5):600–605.
  36. Kurt M, Denton BT, Schafer AJ, et al. The structure of optimal statin initiation policies for patients with Type 2 diabetes. IIE Trans Healthcare Sys Eng. 2011;1(1):49–65.
  37. Lee D, Markwardt SE, McAvay GJ, et al. Effect of beta blockers on cardiac and pulmonary events and death in older adults with cardiovascular disease and chronic obstructive pulmonary disease. Med Care. Mar 2014;52(Suppl. 3):S45-51.
  38. LeRoy L, Bayliss E, Domino ME, et al. The Agency for Healthcare Research and Quality Multiple Chronic Conditions Research Network: research contributions and future priorities. Med Care. Mar 2014;52(Suppl. 3):S15-22.
  39. Lichstein J, Domino ME, Beadles CA, et al. Use of medical homes by patients with comorbid physical and severe mental illness. Med Care. Mar 2014;52(Suppl. 3):S85-91.
  40. Luchins DJ, McCarthy JF, Mach JJ, et al. Quantifying the contribution of VA service-connected disability pensions to the "check effect." Psychiatr Serv. May 2011;62(5):551–553.
  41. Maciejewski M and Bayliss EA. Approaches to comparative effectiveness research in multimorbid populations. Med Care. Mar 2014;52(Suppl. 3):S23-30.
  42. Mack D, Rust GS, Baltrus P, et al. Using appendiceal perforation rates to measure impact of a disaster on healthcare system effectiveness. South Med J. Jan 2013;106(1):82–88.
  43. Mandy G, Malkar M, Welty SE, et al. Tracheostomy placement in infants with bronchopulmonary dysplasia: safety and outcomes. Pediatr Pulmonol. Mar 2013;48(3):245–249.
  44. Mason JE, England DA, Denton BT, et al. Optimizing statin treatment decisions for diabetes patients in the presence of uncertain future adherence. Med Decis Making. Jan–Feb 2012;32(1):154–166.
  45. McCabe RM, Adomavicius G, Johnson PE, et al. Using Data Mining to Predict Errors in Chronic Disease Care [Chapter in online book]. Advances in Patient Safety: New Directions and Alternative Approaches; Vol. 3: Performance and Tools. Rockville, MD: Agency for Healthcare Research and Quality. August 2008. Available from: http://www.ncbi.nlm.nih.gov/books/NBK43675/. Accessed August 31, 2013.
  46. Meyer G, Adomavicius G, Johnson P, et al. A Machine Learning Approach to Improving Dynamic Decision Making. In Press, INFORMS.
  47. Min L, Reuben D, Wenger N. A short functional screening survey is responsible for changes in functional status among vulnerable elders. J Am Geriatr Soc. 2008;58(10):1932–1936.
  48. Min L, Wenger N, Walling AM, et al. When comorbidity, aging, and complexity of primary care meet: development and validation of the Geriatric CompleXity of Care Index. J Am Geriatr Soc. Apr 2013;61(4):542–550.
  49. Min L, Yoon W, Mariano J, et al. The vulnerable elders-13 survey predicts 5-year functional decline and mortality outcomes in older ambulatory care patients. J Am Geriatr Soc. Nov 2009;57(11):2070–2076.
  50. Min LC, Reuben DB, Adams J, et al. Does better quality of care for falls and urinary incontinence result in better participant-reported outcomes? J Am Geriatr Soc. Aug 2011;59(8):1435–1443.
  51. Min LC, Reuben DB, Keeler E, et al. Is patient-perceived severity of a geriatric condition related to better quality of care? Med Care. Jan 2011;49(1):101–107.
  52. Munoz MA, Liu W, Delaney JA, et al. Comparative effectiveness of fish oil versus fenofibrate, gemfibrozil, and atorvastatin on lowering triglyceride levels among HIV-infected patients in routine clinical care. J Acquir Immune Defic Syndr. Jul 2013.
  53. Nichols GA, Gandra SR, Chiou CF, et al. Successes and challenges of insulin therapy for type 2 diabetes in a managed-care setting. Curr Med Res Opin. Jan 2010;26(1):9–15.
  54. Ornstein SM, Jenkins RG, Litvin CB, et al. Preventive services delivery in patients with chronic illnesses: parallel opportunities rather than competing obligations. Ann Fam Med. Jul–Aug 2013;11(4):344–349.
  55. Ornstein SM, Nietert PJ, Jenkins RG, et al. The prevalence of chronic diseases and multimorbidity in primary care practice: A PPRNet Report. J Am Board Fam Med. Sep-Oct 2013;26(5):518–524.
  56. Putcha N, Puhan MA, Hansel NN, et al. Impact of co-morbidities on self-rated health in self-reported COPD: an analysis of NHANES 2001-2008. COPD. Jun 2013;10(3):324–332.
  57. Reuben DB, Magasi S, McCreath HE, et al. Motor assessment using the NIH Toolbox. Neurology. Mar 12 2013;80(11 Suppl. 3):S65–75.
  58. Rogers MA, Ward K, Gure TR, et al. Blood pressure trajectories prior to death in patients with diabetes. Diabetes Care. Jul 2011;34(7):1534–1539.
  59. Rust G, Levine RS, Fry-Johnson Y, et al. Paths to success: optimal and equitable health outcomes for all. J Health Care Poor Underserved. 2012;23(2 Suppl.):7–19.
  60. Sachs GA, Carter R, Holtz LR, et al. Cognitive impairment: an independent predictor of excess mortality: a cohort study. Ann Intern Med. Sep 6 2011;155(5):300–308.
  61. Scheid DC, Hamm RM, Ramakrishnan K, et al. Improving colorectal cancer screening in family medicine: an Oklahoma Physicians Resource/Research Network (OKPRN) study. J Am Board Fam Med. Sep–Oct 2013;26(5):498–507.
  62. Schelfhout JE, Stojanovic DA, Houtchens A, et al. Progression of platelet counts in treatment naive HIV/HCV co-infection. World J AIDS. 2013;3(1):36–40.
  63. Schroeder EB, Hanratty R, Beaty BL, et al. Simultaneous control of diabetes mellitus, hypertension, and hyperlipidemia in 2 health systems. Circ Cardiovasc Qual Outcomes. Sep 1 2012;5(5):645–653.
  64. Shah ND, Mason J, Kurt M, et al. Comparative effectiveness of guidelines for the management of hyperlipidemia and hypertension for type 2 diabetes patients. PLoS One. 2011;6(1):e16170.
  65. Shim RS, Ye J, Baltrus P, et al. Racial/ethnic disparities, social support, and depression: examining a social determinant of mental health. Ethn Dis. Winter 2012;22(1):15–20.
  66. Shippee ND, Shah ND, May CR, et al. Cumulative complexity: a functional, patient-centered model of patient complexity can improve research and practice. J Clin Epidemiol. Oct 2012;65(10):1041–1051.
  67. Singh S, Willig JH, Mugavero MJ, et al. Comparative effectiveness and toxicity of statins among HIV-infected patients. Clin Infect Dis. Feb 1 2011;52(3):387–395.
  68. Slaughter JL, Stenger MR, Reagan PB. Variation in the use of diuretic therapy for infants with bronchopulmonary dysplasia. Pediatrics. Apr 2013;131(4):716–723.
  69. Stenger MR, Slaughter JL, Kelleher K, et al. Hospital variation in nitric oxide use for premature infants. Pediatrics. Apr 2012;129(4):e945–951.
  70. Tai-Seale M, Wilson C, Stone A, et al. Patients' BMI and blood pressure over time: diagnoses, treatments, and the effects of comorbidities. Med Care. Mar 2014; 52(Suppl. 3): S110-117.
  71. Thorpe CT, Flood GE, Kraft SA, et al. Effect of patient selection method on provider group performance estimates. Med Care. Aug 2011;49(8):780–785.
  72. Tinetti ME and Basu J. Research on multiple chronic conditions: where we are and where we need to go. Med Care. Mar 2014; 52(Suppl. 3):S3-6.
  73. Tjia J, Gurwitz JH, Briesacher BA. Challenge of changing nursing home prescribing culture. Am J Geriatr Pharmacother. Feb 2012;10(1):37–46.
  74. Trikalinos TA, Segal J B, Boyd CM. Addressing multimorbidity in evidence integration and synthesis. J Gen Intern Med. Feb 2014:1-9.
  75. Uhlig K, Leff B, Kent DM, et al. A framework for crafting clinical practice guidelines that are relevant to the care and management of people with multimorbidity. J Gen Intern Med. Feb2014:1-10.
  76. Weiss CO, Varadhan R, Puhan MA, et al. Multimorbidity and evidence generation. J Gen Intern Med. Feb 2014:1-8.
  77. Wilkins TL, Rust GS, Sambamoorthi U. Changing BMI categories and healthcare expenditures among elderly Medicare beneficiaries. Obesity (Silver Spring). Jun 2012;20(6):1240–1248.
  78. Wyatt K, Stuart LM, Brito JP, et al. Out of context: clinical practice guidelines and patients with multiple chronic conditions. A systematic review. Med Care. Mar 2014;52(Suppl. 3):S92-100.
  79. Xiao L, Yank V, Wilson SR, et al. Two-year weight-loss maintenance in primary care-based Diabetes Prevention Program lifestyle interventions. Nutr Diabetes. 2013;3:e76.
  80. Yoon J, Zulman D, Scott JY, et al. Costs associated with multimorbidity among VA patients. Med Care. Mar 2014;52(Suppl. 3):S31-36.
  81. Yung VY, Walling AM, Min L, et al. Documentation of advance care planning for community-dwelling elders. J Palliat Med. Jul 2010;13(7):861–867.
  82. Zeng C, Ellis JL, Steiner JF, et al. Assessment of morbidity over time in predicting health outcomes. Med Care. Mar 2014;52(Suppl. 3):S52-59.
  83. Zhang S, Cardarelli K, Shim R, et al. Racial disparities in economic and clinical outcomes of pregnancy among Medicaid recipients. Matern Child Health J. Oct 13 2012.
  84. Zhang Y, Thamer M, Kaufman J, et al. Comparative effectiveness of two anemia management strategies for complex elderly dialysis patients. Med Care. Mar 2014;52(Suppl. 3):S132-139.
  85. Zhang Y, Thamer M, Kaufman JS, et al. High doses of epoetin do not lower mortality and cardiovascular risk among elderly hemodialysis patients with diabetes. Kidney Int. Sep 2011;80(6):663–669.
Page last reviewed May 2014
Internet Citation: AHRQ Multiple Chronic Conditions Research Network Publications. May 2014. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/professionals/prevention-chronic-care/decision/mcc/mccpublications.html