Appendix C

A Companion Guide to the National On the CUSP: Stop BSI Project Final Report

Article Exclusion List with Reason for Exclusion

Author, YearTitleReason for Exclusion
Abramson MA,
2002
Nosocomial methicillin-resistant and methicillin-susceptible Staphylococcus aureus. Primary Bacteremia: At What Costs?Does not pertain to calculated attributable CLABSI cost estimates
Al-Rawajfah OM,
2009
Incidence of and risk factors for nosocomial bloodstream infections in adults in the United States.Does not pertain to calculated attributable CLABSI cost estimates
Armour AD,
2007
The impact of nosocomially-acquired resistant Pseudomonas aeruginosa infection in a burn unit.Does not pertain to calculated attributable CLABSI cost estimates
Arnow PM,
1993
Consequences of intravascular catheter sepsis.Published before 2002
Ben-David D,
2009
Are there differences in hospital cost between patients with nosocomial methicillin-resistant Staphylococcus aureus bloodstream infection and those with methicillin-susceptible S. aureus bloodstream infection?Compares and/or combines CLABSI cost estimates with other HAI
Berenholtz SM,
2004
Eliminating catheter-related bloodstream infections in the intensive care unit.Does not pertain to calculated attributable CLABSI cost estimates
Blot S,
2002
Clinical impact of nosocomial Klebsiella bacteremia in critically ill patients.Does not pertain to calculated attributable CLABSI cost estimates
Blot S,
2005
Clinical and economic outcomes in critically ill patients with nosocomial catheterrelated bloodstream infection.Pertains to hospital(s) not within the United States
Blot S,
2002
Effects of nosocomial candidemia on outcomes of critically ill patients.Does not pertain to calculated attributable CLABSI cost estimates
Blot S,
2003
Reappraisal of attributable mortality in critically ill patients with nosocomial bacteraemia involving Pseudomonas aeruginosa.Does not pertain to calculated attributable CLABSI cost estimates
Blot S,
2003
Evaluation of outcome in critically ill patients with nosocomial enterobacter bacteremia: results of a matched cohort study.Does not pertain to calculated attributable CLABSI cost estimates
Blot S,
2003
Nosocomial bacteremia involving Acinetobacterbaumannii in critically ill patients: a matched cohort study.Does not pertain to calculated attributable CLABSI cost estimates
Blot S,
 2002
Nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in critically ill patients: Clinical outcome and length of hospitalization.Does not pertain to calculated attributable CLABSI cost estimates
Borschel DM,
2006
Are antiseptic-coated central venous catheters effective in a real-world setting?Does not pertain to calculated attributable CLABSI cost estimates
Brun-Buisson C,
2003
The costs of septic syndromes in the intensive care unit and influence of hospital-acquired sepsis.Cost estimates not in U.S. dollars
Burke JP, 
2003
Infection control—a problem for patient safety.Does not pertain to calculated attributable CLABSI cost estimates
Burton DC,
2009
Methicillin-resistant Staphylococcus aureus central line-associated bloodstream infections in US intensive care units, 1997-2007.Does not pertain to calculated attributable CLABSI cost estimates
Carbon C
1999
Costs of treating infections caused by methicillin-resistant staphylococci and vancomycin-resistant enterococci.Published before 2002
Carmeli Y, 2002Health and economic outcomes of vancomyecin resistant enterococci.Does not pertain to CLABSI specific HAI
CDC,
2005
Reduction in central line-associated bloodstream infections among patients in intensive care units—Pennsylvania, April 2001-March 2005Does not pertain to calculated attributable CLABSI cost estimates
CDC,
1992
Public health focus: surveillance, prevention, and control of nosocomial infections.Published before 2002
CDC,
1998
National Nosocomial Infections Surveillance (NNIS) system report, data summary from October 1986- April 1998Published before 2002
CDC,
2011
Vital signs: central line-associated blood stream infections--United States, 2001, 2008, and 2009.Does not pertain to calculated attributable CLABSI cost estimates
Coopersmith CM, 
2002
Effect of an education program on decreasing catheter-related bloodstream infections in the surgical intensive care unit.Does not pertain to calculated attributable CLABSI cost estimates
Correa L,
2000
Problems and solutions in hospital-acquired bacteraemia.Published before 2002
Cosgrove SE,
2006
Evidence that prevention makes cents: Costs of catheter-associated bloodstream infections in the intensive care unit.Does not pertain to calculated attributable CLABSI cost estimates
Cosgrove SE,
2005
The impact of methicillin resistance in Staphylococcus Aureusbacterimia on patient outcomes: mortality, length of stay, and hospital charges.Compares and/or combines CLABSI cost estimates with other HAI
Crawford AG,
2004
Cost-benefit analysis of chlorhexidinegluconate dressing in the prevention of catheter-related bloodstream infections.Does not pertain to calculated attributable CLABSI cost estimates
Curtis LT
2008
Prevention of hospital-acquired infections: review of non-pharmacological interventions.Review, meta-analysis and systematic review articles
DiazGranados CA,
2005
Comparison of mortality associated with  vancomycin-resistant and vancomycin-susceptible enterococcal bloodstream infections: a meta-analysis.Review, meta-analysis and systematic review articles
Digiovine B,
1999
The attributable mortality and costs of primary nosocomial bloodstream infections in the intensive care unit.Published before 2002
Dimick JB,
2001
Increased resource use associated with catheter-related bloodstream infection in the surgical intensive care unit.Published before 2002
Dimick JB,
2001
Intersive care unit physician staffing is associated with decreased length of stay, hospital cost, and complications after espothageal resection.Published before 2002
Dixon RE, 
1987
Costs of nosocomial infections and benefits of infection control programs. In: Wenzel RP, ed. Prevention and Control of Nosocomial Infections, 1st ed.Published before 2002
Donowitz LG,
1987
Neonatal intensive care unit bacteremia: emergence of gram-positive bacteria as major pathogens.Published before 2002
Edmond MB,
1999
Nosocomial bloodstream infections in United States hospitals: a three-year analysis.Published before 2002
Engemann JJ, 2003Adverse clinical and economic outcomes attributable to methicillin resistance among patients with  Staphylococcusaureus surgical site infection.Does not pertain to CLABSI specific HAI
Esatoglu AE,
2006
Additional cost of hospital-acquired infections to the patient: a case study in Turkey.Pertains to hospital(s) not within the United States
Evans RS,
1998
A computer-assisted management program for antibiotics and other anti-infective agents.Published before 2002
Falagas ME,
2006
Attributable mortality of candidemia: a systematic review of matched cohort and case-control studies.Review, meta-analysis and systematic review articles
Fraher MH,
2009
Cost-effectiveness of employing a total parenteral nutrition surveillance nurse for the prevention of catheter-related bloodstream infections.Pertains to hospital(s) not within the United States
Fukuda H,
2011
Variations in analytical methodology for estimating costs of hospital-acquired infections: a systematic review.Review, meta-analysis and systematic review articles
Gagne JJ,
2006
Costs associated with candidemia in a hospital setting.Does not pertain to CLABSI specific HAI
Garrouste-Orgeas M,
2000
A one-year prospective study of nosocomial bacteremia in ICU and non-ICU patients and its impact on patient outcome.Published before 2002
GianinoMS,
1993
The impact of a nutritional support team on the cost and management of multilumen central venous catheters.Published before 2002
Goldstein M,
2000
The medical and financial costs associated with termination of a nutrition support nurse.Published before 2002
Gonzales RD,
2001
Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolid.Published before 2002
Graves N,
2007
Effect of healthcare-acquired infection on length of hospital stay and cost.Pertains to hospital(s) not within the United States
Graves N,
2005
Correcting for bias when estimating the cost of hospital-acquired  infection: an analysis of lower respiratory tract infections in non-surgical patients.Pertains to hospital(s) not within the United States
Graves N,
2007
Economics and preventing hospital acquired infection–broadening the perspective.Simulated cost model
Gudlaugsson O,
2003
Attributable mortality of nosocomial candidemia, revisited.Does not pertain to calculated attributable CLABSI cost estimates
Haley RW,
1991
Measuring the costs of nosocomial infections: methods for estimating economic burden on the hospital.Published before 2002
Haley RW,
1985
The nationwide nosocomial infection rate: a new need for vital statistics.Published before 2002
Haley RW,
1985
 The efficacy of infection surveillance and control programs in preventing nosocomial infections in US hospitals.Published before 2002
Haley RW,
1998
Cost-benefit analysis of infection control activities.Published before 2002
Haley RW, 1987The financial incentive for hospitals to prevent nosocomial infections under the prospective payment system: an empirical determination from a nationally representative sample.Published before 2002
Halton K,
2007
Economic evaluation and catheter-related bloodstream infections.Review, meta-analysis and systematic review articles
Heiselman D,
1994
Nosocomial bloodstream infections in the critically ill.Published before 2002
Herwaldt LA,
2006
A prospective study of outcomes, healthcare resource utilization, and costs associated with postoperative nosocomial infections.Does not pertain to calculated attributable CLABSI cost estimates
Higuera F,
2007
Attributable cost and length of stay for patients with central venous catheter-associated bloodstream infection in Mexico City intensive care units: a prospective, matched analysis.Pertains to hospital(s) not within the United States
Hollenbeak CS
2011
The cost of catheter-related bloodstream infections: implications for the value of prevention.Article not peer reviewed
Hollenbeak CS
2002
Nonrandom selection and the attributable cost of surgical-site infections.Does not pertain to CLABSI specific HAI
Hoste EA,
2004
Effect of nosocomial bloodstream infection on the outcome of critically ill patients with acute renal failure treated with renal replacement therapy.Pertains to hospital(s) not within the United States
Jarvis WR,
1996
Selected aspects of the socioeconomic impact of nosocomial infections: morbidity, mortality, cost and prevention.Published before 2002
Kim JS,
2011
Reduction of catheter-related bloodstream infections through the use of a central venous line bundle: epidemiologic and economic consequences.Does not pertain to calculated attributable CLABSI cost estimates
Klevens RM,
2007
Estimating health care-associated infections and deaths in U.S. hospitals, 2002.Compares and/or combines CLABSI cost estimates with other HAI
Kluger DM,
1999
The relative risk of intravascular device related bloodstream infections in adults [abstract].Published before 2002
Landry SL,
1989
Hospital stay and mortality attributed to nosocomial enterococcal bacteremia: a controlled study.Published before 2002
Laupland KB,
2002
Population based assessment of intensive care unit-acquired bloodstream infections in  adults: incidence, risk factors, and associated mortality rate.Does not pertain to calculated attributable CLABSI cost estimates
Laupland KB,
2006
Cost of intensive care unit-acquired bloodstream infections.Pertains to hospital(s) not within the United States
Li J,
2001
Comparison of length of hospital stay for patients with known or suspected methicillin-resistant Staphylococcus species infections treated with linezolid or vancomycin: a randomized, multi-center trial.Published before 2002
Lodise TP,
2005
Clinical and economic impact of methicillin resistance in patients with staphylococcus aureus bacteremia.Does not pertain to CLABSI specific HAI
Luce B, 1996Estimating costs in cost-effectiveness analysis.Published before 2002
Martin MA,
1989
Coagulase-negative staphylococcal bacteremia: mortality and hospital stay.Published before 2002
McCollum M,
2003
Cost analysis of switching from IV vancomycin to PO linezolid for the management of methicillin-resistant Staphylococcus species.Does not pertain to calculated attributable CLABSI cost estimates
Meier PA,
1998
Impact of a dedicated intravenous therapy team on nosocomial bloodstream infection rates.Published before 2002
Mermel LA,
2000
Prevention of intravascular catheter-related infections.Published before 2002
Mermel LA,
2000
Correction: catheter related bloodstream-infections.Published before 2002
Misset B,
2004
A continuous quality-improvement program reduces nososcomial infection rates in the ICU.Does not pertain to CLABSI specific HAI
Moran C,
2009
Candida albicans and non-albicans bloodstream infections in adult and pediatric patients: comparison of mortality and costs.Does not pertain to calculated attributable CLABSI cost estimates
Morgan J,
2005
Excess mortality, hospital stay, and cost due to candidemia: A case-control study using data from population-based candidemia surveillance.Does not pertain to CLABSI specific HAI
Mullins C,
2006
Cost-effectiveness analysis of linezolid compared with vancomycin for the treatment of nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus.Does not pertain to CLABSI specific HAI
Nehme AE
1980
Nutritional support of the hosptalized patient: the team concept.Published before 2002
Nightingale CH,
1993
Impact of nosocomial infections on hospital costs.Published before 2002
Niven DJ,
2010
Cost and outcomes of nosocomial bloodstream infections complicating major traumatic injury.Pertains to hospital(s) not within the United States
Nixon M,
2006
Methicillin-resistant Staphylococcus aureus on orthopaedic wards: incidence, spread, mortality, cost and control.Cost estimates not in U.S. dollars
Nosrati M,
2010
Excess costs associated with common healthcare-associated infections in an Iranian cardiac surgical unit.Pertains to hospital(s) not within the United States
O'Grady N,
2002
Guidelines for the prevention of intravascular catheter-related infections.Does not pertain to calculated attributable CLABSI cost estimates
Ostrowsky B,
2001
Reality check: should we try to detect and isolate vancomycin-resistant enterococci patients?Published before 2002
Parodi S,
2001
Early switch and early discharge opportunities in intravenous vancomycin treatment of suspected methicillin-resistant staphyloccal species infections.Does not pertain to calculated attributable CLABSI cost estimates
Pennsylvania Health Care Cost Containment Council 2005Hospital-acquired infections in Pennsylvania. PHC4Article not peer reviewed
Pennsylvania Health Care Cost Containment Council
2005
Reducing hospital-acquired infections: the business case. PHC4Article not peer reviewed
Pennsylvania Health Care CostContainment Council
2006
Hospital-acquired infections in Pennsylvania. PHC4Article not peer reviewed
Pirson M,
2005
Costs associated with hospital acquired bacteraemia in a Belgian hospital.Pertains to hospital(s) not within the United States
Pittet D,
1997
Nosocomial bloodstream infections.Published before 2002
Plowman RP,
2001
The rate and cost of hospitalacquired infections occurring in patients admitted to selected specialties of a district general hospital in England and the national burden imposed.Published before 2002
Pronovost P,
2006
An intervention to decrease catheter-related bloodstream infections in the ICU.Does not pertain to calculated attributable CLABSI cost estimates
Puzniak L,
2004
Has the epidemiology of nosocomial candidemia changed?Does not pertain to CLABSI specific HAI
Rello J,
1994
Nosocomial acteremia in a medical-surgical intensive care unit: Epidemiologic characteristics and factors influencing mortality in 111 episodes.Published before 2002
Renaud B,
2001
Outcomes of primary and catheterrelated bacteremia. A cohort and case-control study in critically ill patients.Published before 2002
Rentz AM, 
1998
The impact of candidemia on length of hospital stay, outcome, and overall cost of illness.Published before 2002
Rubin RJ,
1999
The economic impact of Staphylococcus aureus infection in New York City hospitals.Published before 2002
Saint S,
2000
 The clinical and economic consequences of nosocomial central venous catheter-related infection: are antimicrobial catheters useful?Published before 2002
Salgado CD,
2003
Outcomes associated with vancomycin-resistant enterococci: a meta-analysis.Review, meta-analysis and systematic review articles
Sanchez-Velazquez LD,
2006
The burden of nosocomial infection in the intensive care unit: effects on organ failure, mortality and costs. A nested case-control study.Pertains to hospital(s) not within the United States
Scheckler WE,
1980
Hospital costs of nosocomial infections: a prospective three month study in a community hospital.Published before 2002
Shorr AF, 2009Burden of early-onset candidemia: analysis of culture-positive bloodstream infections from a large U.S. database.Does not pertain to CLABSI specific HAI
Shorr AF,
2003
New choices for central venous catheters: potential financial implications.Does not pertain to calculated attributable CLABSI cost estimates
Shorr AF,
2006
Morbidity and cost burden of methicillin-resistant Staphylococcus aureus in early onset ventilator-associated pneumonia.Does not pertain to CLABSI specific HAI
Slonim AD,
2001
Nosocomial bloodstream infection and cost.Published before 2002
Smith SD,
1996
Costs of nosocomial infections.Published before 2002
Song X,
2003
Effect of nosocomial vancomycin- resistant enterococcal bacteremia on mortality, length of stay, and costs.Does not pertain to CLABSI specific HAI
Soufir L,
1999
Attributable morbidity and mortality of catheter-related septicemia in critically ill patients: a matched, risk adjusted, cohort study.Published before 2002
Spengler RF,
1978
Hospital costs and mortality attributed to nosocomial bacteremias.Published before 2002
Steiner C,
2002
The healthcare Cost and Utilization project: an overview.Does not pertain to calculated attributable CLABSI cost estimates
Stevens DL,
2002
Linezolid versus vancomycin for the treatment of methicillin-resistant.Does not pertain to calculated attributable CLABSI cost estimates
Stone PW,
2005
Systematic review of economic analyses of health care-associated infections.Review, meta-analysis and systematic review articles
Stone PW,
2002
A systematic audit of economic evidence linking nosocomial infections and infection control interventions: 1990–2000.Review, meta-analysis and systematic review articles
Stosor V,
1998
Enterococcus faecium bacteremia: does vancomycin resistance make a difference?Published before 2002
Suljagic V,
2005
Nosocomial bloodstream infections in ICU and non-ICU patients.Pertains to hospital(s) not within the United States
Tagalakis V,
2002
The epidemiology of peripheral vein infusion thrombophlebitis: A critical reivew.Does not pertain to CLABSI specific HAI
Tarricone R,
2010
Hospital costs of central line-associated bloodstream infections and cost-effectiveness of closed vs. open infusion containers. The case of Intensive Care Units in Italy.Pertains to hospital(s) not within the United States
Taylor GJ,
1990
Determinants of hospital charges for coronary artery bypass surgery: the economic consequences of postoperative complications.Published before 2002
Teres D,
2002
Effects of severity of illness on resource use by survivors and nonsurvivors of severe sepsis at intensive care unit admission.Compares and/or combines CLABSI cost estimates with other HAI
Tomford JW,
1985
The IV therapy team: impact on patient care and costs of hospitalization.Published before 2002
Tompkins RG,
1992
Infections of Burn Wounds. 3rd ed.Published before 2002
Toufen C,
2003
Prevalence rates of infection in intensive care units of a tertiary teaching hospital.Pertains to hospital(s) not within the United States
Turpin, RS
2011
Nutrition therapy cost analysis in the US pre-mixed multi-chamber bag versus compounded parenteral nutrition.Does not pertain to calculated attributable CLABSI cost estimates
Umscheid CA,
2011
Estimating the proportion of healthcare-associated infections that are reasonably preventable and the related mortality and costs.Does not pertain to calculated attributable CLABSI cost estimates
US Department of Health
& Human Services
2008
Part II: Department of Health and Human Services: Centers for Medicare & Medicaid Services. 42 CFR.Does not pertain to CLABSI specific HAI
Valles J,
1997
Nosocomial bacteremia in critically ill patients: A multicenter study evaluating epidemiology and prognosis.Published before 2002
Vincent JL
2003
Nosocomial infections in adult intensive –care units.Review, meta-analysis and systematic review articles
Vincent J-L,
1995
The prevalence of nosocomial infection in intensive care units in Europe: Results of the European Prevalence of Infection in Intensive Care (EPIC) study.Published before 2002
Vogel TR,
2006
The open abdomen in trauma.Does not pertain to CLABSI specific HAI
Vrijens F,
2010
Hospital-acquired, laboratory-confirmed bloodstream infections: linking national surveillance data to clinical and financial hospital data to estimate increased length of stay and healthcare costs.Pertains to hospital(s) not within the United States
Wakefield DS,
1987
Use of the appropriateness evaluation protocol for estimating the incremental costs associated with nosocomial infections.Published before 2002
Warren DK,
2004
The effect of an education program on the incidence of central venous catheter-associated bloodstream infection in a medical ICU.Does not pertain to calculated attributable CLABSI cost estimates
Warren DK,
2004
Occurrence of co-colonization or co-infection with vancomycin-resistant enterococci and methicillinresistant Staphylococcus aureus in a medical intensive care unit.Does not pertain to calculated attributable CLABSI cost estimates
Waters HR,
2011
The business case for quality: economic analysis of the Michigan Keystone Patient Safety Program in ICUs.Does not pertain to calculated attributable CLABSI cost estimates
Weinstein RA
1998
Nosocomial infection update.Published before 2002
Weintraub WS,
1989
Determinants of prolonged length of stay after coronary bypass surgery.Published before 2002
Wenzel RP
1995
The economics of nosocomial infections.Published before 2002
Wenzel RP,
1991
Feasible and desirable future targets for reducing the costs of hospital infections.Published before 2002
Wenzel RP, 2001The impact of hospital-acquired bloodstream infections.Published before 2002
Wey SB,
1988
Hospital acquired candidemia: the attributable mortality and excess length of stay.Published before 2002
Wisplinghoff H,
2003
Outcomes of nosocomial bloodstream infections in adult neutropenic patients: a prospective cohort and matched case-control study.Pertains to hospital(s) not within the United States
Wisplinghoff H,
2004
Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study.Does not pertain to calculated attributable CLABSI cost estimates
Ye X,
2011
Economic impact of use of chlorhexidine-impregnated sponge dressing for prevention of central line-associated infections in the United States.Does not pertain to calculated attributable CLABSI cost estimates
Young EM,
2006
Translating evidence into practice to prevent central venous catheter-associated bloodstream infections: a systems-based intervention.Does not pertain to calculated attributable CLABSI cost estimates
Young LS,
2006
Preoperative use of mupirocin for the prevention of healthcare-associated Staphylococcus aureus infections: a cost-effectiveness analysis.Does not pertain to CLABSI specific HAI
Zack JE,
2002
Effect of an education program aimed at reducing the occurrence of ventilator-associated pneumonia.Does not pertain to calculated attributable CLABSI cost estimates
Zaoutis TE,
2005
The epidemiology and attributable outcomes of candidemia in adults and children hospitalized in the United States: a propensity analysis.Does not pertain to CLABSI specific HAI
Current as of January 2013
Internet Citation: Appendix C: A Companion Guide to the National On the CUSP: Stop BSI Project Final Report. January 2013. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/professionals/quality-patient-safety/cusp/using-cusp-prevention/clabsi-final-companion/clabsicompapc.html