Reducing Central Line Bloodstream Infections and Ventilator-Associated Pneumonia

Theodore Speroff, Ph.D., Vanderbilt University School of Medicine and HCA, Nashville, TN AHRQ Grant No. HS015934-01


This project couples two interventions to improve critical care—reduction of catheter-related blood stream infections and ventilator-associated pneumonia. The project used a randomized controlled trial to compare the effectiveness of various strategies for implementing an improvement initiative. The toolkit includes:

  • Educational materials.
  • Surveys for infection control and safety.
  • Information on collaborative improvement strategies.
  • Checklists to monitor the bundled processes of care.
  • Guide and template worksheets for initiating a quality improvement team and maintaining continuous action plans.

Target Audience

Physicians, nurses, quality and safety professionals.

Health Care Setting

Intensive care units.

Toolkit Web Site{30E376EA-1232-4B78-9AF3-95B6E565A847}.

Press Releases

AHRQ Awards More Than $8 Million To Further Implementation of Evidence-Based Patient Safety Findings
June 8, 2005

Presentation Slides

The Safe Critical Care Initiative
Date: September 8, 2008
Venue: AHRQ 2008 Annual Conference

Journal Articles

Delirium and sedation in the intensive care unit: survey of behaviors and attitudes of 1384 healthcare professionals. Patel RP, Gambrell M, Speroff T, Scott TA, Pun BT, Okahashi J, Strength C, Pandharipande P, Girard TD, Burgess H, Dittus RS, Bernard GR, Ely EW. Crit Care Med. 2009 Mar;37(3):825-32.

Return to Contents

Current as of October 2004
Internet Citation: Reducing Central Line Bloodstream Infections and Ventilator-Associated Pneumonia. October 2004. Agency for Healthcare Research and Quality, Rockville, MD.