Figure 2: Schematic of Proposed Model (Text Description)

Ovarian Cancer Prevention

Figure 2: Schematic of Proposed Model (Text Description)

Figure 2 depicts a schematic view of the flow of events to be considered in the proposed model. The model begins with a woman's reproductive history (shaded box, detailed in Figure 3) and proceeds through the subsequently available intermediate states: hysterectomy, bilateral oophorectomy, undetected ovarian cancer (stages I, II, III, and IV), detected ovarian cancer (stages I, II, III, and IV), and ovarian cancer survivor. The final outcomes of the model are death from ovarian cancer and death from other causes. Ovarian cancer can either be detected at a given stage or progress to the next stage prior to detection. Ovarian cancer risk may be modified by use of OCs or by hysterectomy or oophorectomy for another indication. Because OCs may affect the risk of these other indications, they may indirectly affect ovarian cancer risk.

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