Evidence-based Practice Center Reports by Year

This page lists all Evidence-based Practice Center reports in reverse chronological order, with the most recent releases on top.

 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 |
1999 | 1998

The following reports are included:

Systematic Reviews

  • Evidence Reports
  • Comparative Effectiveness Reviews
  • Technology Assessment Program Reports
  • U.S. Preventive Service Task Force Evidence Syntheses

Technical Briefs
Methods Research Reports
Research White Papers
Methods Research on Future Research Needs Papers
Future Research Needs Papers
Technical Reviews

2014

Systematic Reviews

Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (September 2014)
Negative Pressure Wound Therapy Technologies for Chronic Wound Care in the Home Setting (September 2014)
Screening for Gonorrhea and Chlamydia, Update (September 2014)
Behavioral Sexual Risk Reduction Counseling in Primary Care to Prevent Sexually Transmitted Infections, Update (September 2014)
Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma (September 2014)
Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update) (September 2014)
Chronic Urinary Retention: Comparative Effectiveness and Harms of Treatments (September 2014)
Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (September 2014)
Imaging Tests for the Staging of Colorectal Cancer (September 2014)
Behavioral Counseling to Promote a Healthy Lifestyle for Cardiovascular Disease Prevention in Persons With Cardiovascular Risk Factors (August 2014)
Molecular Pathology Testing for the Estimation of Prognosis for Common Cancers (August 2014)
Cardiac Troponins Used as Diagnostic and Prognostic Tests in Patients With Kidney Disease (August 2014)
Therapies for Children With Autism Spectrum Disorder: Behavioral Interventions Update (August 2014)
Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (July 2014)
Screening for Asymptomatic Carotid Artery Stenosis (July 2014)
Safety of Vaccines Used for Routine Immunization in the United States (July 2014)
Screening for Hepatitis B Virus Infection in Nonpregnant Adolescents and Adults (May 2014)
Pharmacotherapy for Adults With Alcohol Use Disorders in Outpatient Settings (May 2014)
Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (May 2014)
Low-Dose Aspirin for the Prevention of Morbidity and Mortality From Preeclampsia (April 2014)
Oral Mechanical Bowel Preparation for Colorectal Surgery (April 2014)
Primary Care Behavioral Interventions to Prevent or Reduce Illicit Drug and Nonmedical Pharmaceutical Use in Children and Adolescents: A Systematic Evidence Review for the U.S. Preventive Services Task Force (March 2014)
Smoking Cessation Interventions in Pregnancy and Postpartum Care (February 2014)
Combination Therapy Versus Intensification of Statin Monotherapy: An Update (February 2014)
Pharmacologic Therapies for the Management of Crohn's Disease: Comparative Effectiveness (February 2014)
Benefits and Harms of Routine Preoperative Testing: Comparative Effectiveness (January 2014)
Meditation Programs for Psychological Stress and Well-Being (January 2014)
Primary Care Screening for Abdominal Aortic Aneurysm: A Systematic Evidence Review for the U.S. Preventive Services Task Force (January 2014)
 

Technical Briefs

Imaging Techniques for Treatment Evaluation for Metastatic Breast Cancer (October 2014)
Decision Aids for Advance Care Planning (July 2014)
Transition Care for Children With Special Health Needs (June 2014)
Models of Cancer Survivorship Care (March 2014)

Methods Research Reports

The Empirical Evidence of Bias in Trials Measuring Treatment Differences (September 2014)
Use of Evidence-based Practice Center Comparative Effectiveness Reviews by Clinical Point-of-Care Tools (April 2014)
Developing and Assessing Contextual Frameworks for Research on the Implementation of Complex System Interventions (March 2014)
 

Research White Papers

Integration of Existing Systematic Reviews (June 2014)
Impact of Contacting Study Authors on Systematic Review Conclusions: Diagnostic Tests for Hepatic Fibrosis (April 2014)
Observational Evidence and Strength of Evidence Domains: Case Examples (April 2014)
Systematic Reviews of Complex Multicomponent Health Care Interventions (March 2014)
Assessment of a Method To Detect Signals for Updating Systematic Reviews (March 2014)
Defining the Benefits of Stakeholder Engagement in Systematic Reviews (March 2014)
 

Future Research Needs Papers

Pharmacological Management of Crohn's Disease: Future Research Needs (April 2014)
Chronic Venous Leg Ulcer Treatment: Future Research Needs (January 2014)
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2013

Systematic Reviews

Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: Systematic Review to Update the U.S. Preventive Services Task Force Recommendation  (December 2013)
Chronic Venous Ulcers: A Comparative Effectiveness Review of Treatment Modalities (December 2013)
Long-Term Care for Older Adults: Future Research Needs (November 2013)
Vitamin, Mineral, and Multivitamin Supplements for the Primary Prevention of Cardiovascular Disease and Cancer: A Systematic Evidence Review for the U.S. Preventive Services Task Force (November 2013)
Communication and Dissemination Strategies To Facilitate the Use of Health-Related Evidence (November 2013)
Screening for Cognitive Impairment in Older Adults: An Evidence Update for the U.S. Preventive Services Task Force (November 2013)
Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction (November 2013)
Use of Natriuretic Peptide Measurement in the Management of Heart Failure (November 2013)
The Ankle Brachial Index for Peripheral Artery Disease Screening and Cardiovascular Disease Prediction in Asymptomatic Adults: A Systematic Evidence Review for the U.S. Preventive Services Task Force (September 2013)
Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (September 2013)
Stroke Prevention in Atrial Fibrillation (August 2013)
Evaluation and Treatment of Tinnitus: Comparative Effectiveness (August 2013)
Interventions for Adult Offenders With Serious Mental Illness (August 2013)
Treatments for Seasonal Allergic Rhinitis (July 2013)
Update on Genetic Tests Currently Available for Clinical Use in Common Cancers (July 2013)
Screening for Lung Cancer: Systematic Review to Update the U.S. Preventive Services Task Force Recommendation (July 2013)
Treatment of Atrial Fibrillation (June 2013)
Childhood Obesity Prevention Programs: Comparative Effectiveness Review and Meta-Analysis (June 2013)
Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non–Small-Cell Lung Cancer (June 2013)
Migraine in Children: Preventive Pharmacologic Treatments (June 2013)
Oral Contraceptive Use for the Primary Prevention of Ovarian Cancer (June 2013)
Screening for Methicillin-Resistant Staphylococcus Aureus (MRSA) (June 2013)
Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m² (June 2013)
Assessment on Implantable Defibrillators and the Evidence for Primary Prevention of Sudden Cardiac Death (June 2013)
Otitis Media With Effusion: Comparative Effectiveness of Treatments (May 2013)
Treatment Strategies for Patients With Peripheral Artery Disease (May 2013)
Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special Populations (May 2013)
Local Therapies for Unresectable Primary Hepatocellular Carcinoma (May 2013)
Pressure Ulcer Treatment Strategies: Comparative Effectiveness (May 2013)
Pressure Ulcer Risk Assessment and Prevention: Comparative Effectiveness (May 2013)
Interventions To Modify Health Care Provider Adherence to Asthma Guidelines (May 2013)
Pulmonary Arterial Hypertension: Screening, Management, and Treatment (April 2013)
Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment: Comparative Effectiveness Update (April 2013)
Interventions for the Prevention of Posttraumatic Stress Disorder (PTSD) in Adults After Exposure to Psychological Trauma (April 2013)
Migraine in Adults: Preventive Pharmacologic Treatments (April 2013)
Efficacy and Safety of Screening for Postpartum Depression (April 2013)
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) (April 2013)
Child Exposure to Trauma: Comparative Effectiveness of Interventions Addressing Maltreatment (April 2013)
Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness (April 2013)
PCA3 Testing for the Diagnosis and Management of Prostate Cancer (April 2013)
Screening for Suicide Risk in Primary Care: A Systematic Evidence Review for the U.S. Preventive Services Task Force (April 2013)
Screening for Oral Cancer: A Targeted Evidence Update for the U.S. Preventive Services Task Force (April 2013)
Interventions for Feeding and Nutrition in Cerebral Palsy (March 2013)
Allergen-Specific Immunotherapy for the Treatment of Allergic Rhinoconjunctivitis and/or Asthma: Comparative Effectiveness Review (March 2013)
Wireless Motililty Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation: A Comparative Effectiveness Review (March 2013)
Making Health Care Safer II: An Updated Critical Analysis of the Evidence for Patient Safety Practices (March 2013)
Strategies To Prevent Weight Gain Among Adults (March 2013)
Primary Care Management of Abnormal Uterine Bleeding (March 2013)
Child and Adolescent Exposure to Trauma: Comparative Effectiveness of Interventions Addressing Trauma Other Than Maltreatment or Family Violence (February 2013)
Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Comparative Effectiveness Review (February 2013)
Fluorescence In Situ Hybridization (FISH) or Other In Situ Hybridization (ISH) Testing of Uterine Cervical Cells to Predict Precancer and Cancer (February 2013)
Technology Assessment on Genetic Testing or Molecular Pathology Testing of Cancers with Unknown Primary Site to Determine Origin (February 2013)
Screening for Hypertension in Children and Adolescents to Prevent Cardiovascular Disease: Systematic Review for the U.S. Preventive Services Task Force (February 2013)
Assessment and Management of Chronic Cough (January 2013)
Outpatient Case Management for Adults With Medical Illness and Complex Care Needs: A Comparative Effectiveness Review (January 2013)
Behavioral Interventions and Counseling to Prevent Child Abuse and Neglect: Systematic Review to Update the U.S. Preventive Services Task Force Recommendation (January 2013)

Technical Briefs

Enzyme-Replacement Therapies for Lysosomal Storage Diseases (January 2013)

Methods Research Reports

Simulation-Based Comparison of Methods for Meta-Analysis of Proportions and Rates (November 2013)
Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (September 2013)
Assessing Risk of Bias and Confounding in Observational Studies of Interventions or Exposures: Further Development of the RTI Item Bank (August 2013)
Surveillance and Identification of Signals for Updating Systematic Reviews: Implementation and Early Experience (June 2013)
Identifying and Managing Nonfinancial Conflicts of Interest for Systematic Reviews (May 2013)
Progression-Free Survival: What Does It Mean for Psychological Well-Being or Quality of Life? (April 2013)
Meta-Analytic Statistical Inferences for Continuous Measure Outcomes as a Function of Effect Size Metric and Other Assumptions (April 2013)
Case Study Comparing Bayesian and Frequentist Approaches for Multiple Treatment Comparisons (March 2013)
Empirical Simulation-Based Comparison of Univariate and Multivariate Meta-Analysis for Binary Outcomes (March 2013)
Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis (March 2013)
Decision and Simulation Modeling in Systematic Reviews (February 2013)
Framework for Determining Research Gaps During Systematic Review: Evaluation (February 2013)
Findings of Bayesian Mixed Treatment Comparison Meta-Analyses: Comparison and Exploration Using Real-World Trial Data and Simulation (January 2013)
Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test Accuracy: Methods for the Joint Meta-Analysis of Multiple Tests (January 2013)
A Bayesian Missing Data Framework for Multiple Continuous Outcome Mixed Treatment Comparisons (January 2013)
Assessing the Accuracy of Google Translate To Allow Data Extraction From Trials Published in Non-English Languages (January 2013)

Research White Papers

Observational Studies: Empirical Evidence of Their Contributions to Comparative Effectiveness Reviews (December 2013)
A Primer for Systematic Reviewers on the Measurement of Functional Status and Health-Related Quality of Life in Older Adults (September 2013)
Global Health Evidence Evaluation Framework (June 2013)
Mechanistic Evidence in Evidence-Based Medicine: A Conceptual Framework (June 2013)
Reporting the Findings of Updated Systematic Reviews of Comparative Effectiveness: How Do Users Want To View New Information?  (May 2013)
EPC Response to IOM Standards for Systematic Reviews (April 2013)
Role of Single Group Studies in Agency for Healthcare Research and Quality Comparative Effectiveness Reviews (January 2013)

Methods Research on Future Research Needs Papers

Prioritization Criteria Methodology for Future Research Needs Proposals Within the Effective Health Care Program (January 2013)

Future Research Needs Papers

Strategies To Prevent Weight Gain in Adults: Future Research Needs (August 2013)
Screening for Methicillin-Resistant Staphylococcus aureus (MRSA): Future Research Needs (June 2013)
Future Research Needs for Childhood Obesity Prevention Programs (June 2013)
Wireless Motility Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation: Future Research Needs (May 2013)
Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs (April 2013)
Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs (April 2013)
Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Future Research Needs (April 2013)
PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs (April 2013)
Insulin Delivery and Glucose Monitoring Methods: Future Research Needs (March 2013)
Treatment Strategies for Women With Coronary Artery Disease: Future Research Needs (February 2013)
Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs (February 2013)
Nonoperative and Operative Treatments for Rotator Cuff Tears: Future Research Needs (February 2013)
Treatment for Restless Legs Syndrome: Future Research Needs (February 2013)
Physical Therapy for Knee Pain Secondary to Osteoarthritis: Future Research Needs (February 2013)
Future Research Needs: Interventions for Adolescents and Young Adults With Autism Spectrum Disorders (February 2013)
Multidisciplinary Rehabilitation Programs for Moderate to Severe Traumatic Brain Injury in Adults: Future Research Needs (January 2013)
Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs (January 2013)
Outpatient Case Management for Adults With Medical Illnesses and Complex Care Needs: Future Research Needs (January 2013)
Future Research Needs on Procalcitonin-Guided Antibiotic Therapy (January 2013)

Technical Reviews

Concordance Between the Findings of Epidemiological Studies and Randomized Trials in Nutrition (May 2013)

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2012

Systematic Reviews

Skin Substitutes for Treating Chronic Wounds: Final Report (December 2012)
Primary Care Relevant Interventions for Tobacco Use Prevention and Cessation in Children and Adolescents (December 2012)
Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer (December 2012)
Evaluation and Treatment of Cryptorchidism (December 2012)
Interventions To Improve Patient Adherence to Hepatitis C Treatment: Comparative Effectiveness (December 2012)
Screening and Diagnosing Gestational Diabetes Mellitus (November 2012)
Treatment for Restless Legs Syndrome (November 2012)
Biologic and Nonbiologic Systemic Agents and Phototherapy for Treatment of Chronic Plaque Psoriasis (November 2012)
Acute Migraine Treatment in Emergency Settings (November 2012)
Long-Term Care for Older Adults: A Review of Home and Community-Based Services Versus Institutional Care (November 2012)
Physical Therapy Interventions for Knee Pain Secondary to Osteoarthritis (November 2012)
Treatment for Hepatitis C Virus Infection in Adults (November 2012)
Screening for Hepatitis C Virus Infection in Adults (November 2012)
Screening for HIV in Pregnant Women: Systematic Review to Update the U.S. Preventive Services Task Force Recommendation (November 2012)
Screening for HIV: Systematic Review to Update the U.S. Preventive Services Task Force Recommendation (November 2012)
Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease (October 2012)
Strategies To Reduce Cesarean Birth in Low-Risk Women (October 2012)
Comparison of Characteristics of Nursing Homes and Other Residential Long-Term Care Settings for People With Dementia (October 2012)
Procalcitonin-Guided Antibiotic Therapy (October 2012)
Challenges in Synthesizing and Interpreting the Evidence From a Systematic Review of Multifactorial Interventions to Prevent Functional Decline in Older Adults (October 2012)
Progestogens for Prevention of Preterm Birth (September 2012)
Breathing Exercises and/or Retraining Techniques in the Treatment of Asthma: Comparative Effectiveness (September 2012)
Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias (August 2012)
Practice-Based Interventions Addressing Concomitant Depression and Chronic Medical Conditions in the Primary Care Setting (August 2012)
Surgical Options for Inguinal Hernia: Comparative Effectiveness Review (August 2012)
Nitrous Oxide for the Management of Labor Pain (August 2012)
Treatment Strategies for Women With Coronary Artery Disease (August 2012)
First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness (August 2012)
Interventions for Adolescents and Young Adults With Autism Spectrum Disorders (August 2012)
Management of Asymptomatic Carotid Stenosis (August 2012)
Multigene Panels in Prostate Cancer Risk Assessment (July 2012)
Closing the Quality Gap: Revisiting the State of the Science Series (July 2012–February 2013)

Noninvasive Positive-Pressure Ventilation (NPPV) for Acute Respiratory Failure (July 2012)
Screening, Behavioral Counseling, and Referral in Primary Care To Reduce Alcohol Misuse (July 2012)
Recurrent Nephrolithiasis in Adults: Comparative Effectiveness of Preventive Medical Strategies (July 2012)
Methods for Insulin Delivery and Glucose Monitoring: Comparative Effectiveness (July 2012)
Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women (June 2012)
Drug Therapy for Rheumatoid Arthritis in Adults: An Update (June 2012)
Drug Therapy for Psoriatic Arthritis in Adults: Update of a 2007 Report (June 2012)
Allocation of Scarce Resources During Mass Casualty Events (June 2012)
Enabling Patient-Centered Care Through Health IT (June 2012)
Multidisciplinary Postacute Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults (June 2012)
Systematic Review of ECG-based Signal Analysis Technologies for Evaluating Patients With Acute Coronary Syndrome (June 2012)
Update on Mapping the Landscape of Genetic Tests for Non-Cancer Diseases/Conditions (May 2012)
Systematic Review of Decision Tools and their Suitability for Patient-Centered Decisionmaking regarding Electronic Cardiac Device (May 2012)
Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: Systematic Review to Update the 2002 and 2005 U.S. Preventive Services Task Force Recommendations (May 2012)
Screening Women for Intimate Partner Violence and Elderly and Vulnerable Adults for Abuse: Systematic Review to Update the 2004 U.S. Preventive Services Task Force Recommendation (May 2012)
Treatment for Depression After Unsatisfactory Response to SSRIs (April 2012)
Treatment for Glaucoma: Comparative Effectiveness (April 2012)
Screening for Glaucoma: Comparative Effectiveness (April 2012)
Dietary Supplements in Adults Taking Cardiovascular Drugs (April 2012)
Enabling Health Care Decisionmaking Through Clinical Decision Support and Knowledge Management (April 2012)
Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children (April 2012)
Nonsurgical Treatments for Urinary Incontinence in Adult Women: Diagnosis and Comparative Effectiveness (April 2012)
Measuring Health-Related Quality of Life for Patients with Diabetic Retinopathy (April 2012)
Treatments To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis: Update of a 2007 Report (March 2012)
Venous Thromboembolism Prophylaxis in Orthopedic Surgery (March 2012)
Diagnosis and Management of Febrile Infants (0–3 Months) (March 2012)
The Impact of Pre-transplant Red Blood Cell Transfusions in Renal Allograph Rejection (March 2012)
Adjuvant Treatment for Phenylketonuria (February 2012)
Fecal DNA Testing in Screening for Colorectal Cancer in Average-Risk Adults (February 2012)
Hematopoietic Stem Cell Transplantation in the Pediatric Population (February 2012)
Noninvasive Diagnostic Tests for Breast Abnormalities: Update of a 2006 Review (February 2012)
First- and Second-Generation Antipsychotics for Children and Young Adults (February 2012)
Self-Measured Blood Pressure Monitoring: Comparative Effectiveness (January 2012)
Noncyclic Chronic Pelvic Pain Therapies for Women: Comparative Effectiveness (January 2012)
Chronic Kidney Disease Stages 1–3: Screening, Monitoring, and Treatment (January 2012)

Technical Briefs

Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (December 2012)
Wheeled Mobility (Wheelchair) Service Delivery (January 2012)

Methods Research Reports

An Empirical Assessment of Bivariate Methods for Meta-Analysis of Test Accuracy (November 2012)
Empirical Assessment of Within-Arm Correlation Imputation in Trials of Continuous Outcomes (November 2012)
Methods for Benefit and Harm Assessment in Systematic Reviews (November 2012)
Quality of Reporting in Systematic Reviews of Implantable Medical Devices (November 2012)
Assessing the Impact of Economic Evidence on Policymakers in Health Care—A Systematic Review (October 2012)
Usefulness of Economic Evaluation Data in Systematic Reviews of Evidence (October 2012)
Best Practices for Conducting Economic Evaluations in Health Care: A Systematic Review of Quality Assessment Tools (October 2012)
A Pilot Study Using Machine Learning and Domain Knowledge To Facilitate Comparative Effectiveness Review Updating (September 2012)
Machine Learning Methods in Systematic Reviews: Identifying Quality Improvement Intervention Evaluations (September 2012)
Use of Mixed Treatment Comparisons in Systematic Reviews (August 2012)
Systematizing the Use of Value of Information Analysis in Prioritizing Systematic Reviews (August 2012)
Peer Review of Search Strategies (June 2012)
Assessing Equivalence and Noninferiority (June 2012)
Reliability Testing of the AHRQ EPC Approach To Grading the Strength of Evidence in Comparative Effectiveness Reviews (May 2012)
Accuracy of Data Extraction of Non–English-Language Trials With Google Translate (April 2012)
Validity and Inter-rater Reliability Testing of Quality Assessment Instruments (March 2012)
Comprehensive Overview of Methods and Reporting of Meta-Analyses of Test Accuracy (March 2012)
OpenMetaAnalyst: Powerful Open-Source Software for Meta-Analysis (February 2012)
Detection of Associations Between Trial Quality and Effect Sizes (January 2012)

Research White Papers

Proposed Governance and Data Management Policy for the Systematic Review Data Repository (September 2012)
Systematic Review Data Repository (July 2012)
A Framework to Facilitate the Use of Systematic Reviews and Meta-Analyses in the Design of Primary Research Studies (January 2012)

Methods Research on Future Research Needs Papers

Presentation of Future Research Needs (April 2012)
Framework for Considering Study Designs for Future Research Needs (March 2012)

Future Research Needs Papers

Future Research Needs To Reduce Cesarean Birth in Low-Risk Women (October 2012)
Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias: Future Research Needs (September 2012)
Adjuvant Treatment for Phenylketonuria: Future Research Needs (September 2012)
Future Research Needs for Noncyclic Chronic Pelvic Pain Therapies for Women (September 2012)
Future Research Needs for the Comparative Effectiveness of Breathing Exercises and/or Retraining Techniques in the Treatment of Asthma (September 2012)
Self-Measured Blood Pressure: Future Research Needs (August 2012)
Future Research Needs for Prevention and Treatment of Clostridium difficile Infection (May 2012)
Vaginal Birth After Cesarean: Developing and Prioritizing a Future Research Agenda (May 2012)
Future Research Needs for Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), or Direct Renin Inhibitors (DRIs) for Treating Hypertension (March 2012)
Future Research Needs for First- and Second-Generation Antipsychotics for Children and Young Adults (February 2012)
Future Research Needs for Treatment of Obstructive Sleep Apnea (February 2012)
Future Research Needs for Diagnosis of Obstructive Sleep Apnea (February 2012)
Future Research Needs for Hematopoietic Stem-Cell Transplantation in the Pediatric Population (February 2012)
Future Research Needs for Attention Deficit Hyperactivity Disorder—Effectiveness of Treatment in At-Risk Preschoolers; Long-Term Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment (January 2012)

Technical Reviews

Comparison of Translational Patterns in Two Nutrient–Disease Associations (February 2012)
Effects of Eicosapentanoic and Docosahexanoic Acid on Mortality (February 2012)

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2011

Systematic Reviews

An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer (December 2011)
Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression: An Update of the 2007 Comparative Effectiveness Review (December 2011)
Adjunctive Devices for Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention (December 2011)
Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy (December 2011) (Archived)
Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile Infection (December 2011)
Screening and Treatment of Subclinical Hypothyroidism or Hyperthyroidism (November 2011)
Transition of Care for Acute Stroke and Myocardial Infarction Patients: From Hospitalization to Rehabilitation, Recovery, and Secondary Prevention (October 2011)
Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers; Long-Term Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment (October 2011)
Analgesics for Osteoarthritis: An Update of the 2006 Comparative Effectiveness Review (October 2011)
Treatments for Localized Prostate Cancer: Systematic Review to Update the 2002 U.S. Preventive Services Task Force Recommendation (October 2011)
Prostate-Specific Antigen-Based Screening for Prostate Cancer: An Evidence Update for the U.S. Preventive Services Task Force (October 2011)
Screening for and Management of Obesity and Overweight in Adults (October 2011)
Screening Asymptomatic Adults for Coronary Heart Disease With Resting or Exercise Electrocardiography (September 2011)
Terbutaline Pump for the Prevention of Preterm Birth (September 2011) (Archived)
Off-Label Use of Atypical Antipsychotics: An Update (September 2011)
Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults (September 2011)
Comparative Effectiveness of Management Strategies for Gastroesophageal Reflux Disease: Update (September 2011)
Disease-Modifying Antirheumatic Drugs (DMARDS) in Children With Juvenile Idiopathic Arthiritis (JIA) (September 2011) (Archived)
Diagnosis and Treatment of Obstructive Sleep Apnea in Adults (August 2011)
Health Risk Appraisal (July 2011)
Common Syndromes in Older Adults Related to Primary and Secondary Prevention (July 2011)
Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), and Direct Renin Inhibitors for Treating Essential Hypertension: An Update (June 2011)
Pain Management Interventions for Hip Fracture (May 2011)
Lifestyle Interventions for Four Conditions: Breast Cancer, Prostate Cancer, Type 2 Diabetes Mellitus, and Metabolic Syndrome (May 2011)
Screening for Cervical Cancer: A Systematic Evidence Review for the U.S. Preventive Services Task Force (May 2011)
Screening for Cervical Cancer: A Decision Analysis for the U.S. Preventive Services Task Force (May 2011)
Systematic Review of Cardiovascular Disease Risk Assessment Tools (May 2011)
Enabling Medication Management Through Health Information Technology (Health IT) (April 2011)
Safety of Probiotics Used to Reduce Risk and Prevent or Treat Disease (April 2011) 
Traumatic Brain Injury and Depression (April 2011)
Effectiveness of Cochlear Implants in Adults with Sensorineural Hearing Loss (April 2011)
Update of Horizon Scans of Genetic Tests Currently Available for Clinical Use in Cancers (April 2011)
Oral Diabetes Medications for Adults with Type 2 Diabetes: An Update (March 2011)
Health Literacy Interventions and Outcomes: An Updated Systematic Review (March 2011)
Values of Older Adults Related to Primary and Secondary Prevention (March 2011)
Screening for Hearing Loss in Adults Ages 50 Years and Older: A Review of the Evidence for the U.S. Preventive Services Task Force (March 2011)
Behavioral Counseling to Prevent Skin Cancer: Systematic Evidence Review to Update the 2003 U.S. Preventive Services Task Force Recommendation (February 2011)
Screening for Visual Impairment in Children Ages 1-5 Years: Systematic Review to Update the 2004 U.S. Preventive Services Task Force Recommendation (February 2011)
Outcomes of Sipuleucel-T Therapy (February 2011)

Technical Briefs

Emerging MRI Technologies for Imaging Musculoskeletal Disorders Under Loading Stress (October 2011)
Noninvasive Diagnostic Techniques for the Detection of Skin Cancers (September 2011) (Archived)
Multidisciplinary Pain Programs for Chronic Noncancer Pain (September 2011) (Archived)
Neurothrombectomy Devices for Treatment of Acute Ischemic Stroke (July 2011) (Archived)
Stereotactic Body Radiation Therapy (May 2011) (Archived)
Maternal-Fetal Surgical Procedures (April 2011) (Archived)

Methods Research Reports

A Process for Robust and Transparent Rating of Study Quality: Phase 1 (November 2011)
Correcting for Publication Bias in the Presence of Covariates (September 2011)
Development of the RTI Item Bank on Risk of Bias and Precision of Observational Studies (September 2011)
Feasibility Study of a Wiki Collaboration Platform for Systematic Reviews (September 2011)
Bayesian Approaches to Indirect Comparisons (September 2011)
A Framework for "Best Evidence" Approaches in Systematic Reviews (June 2011)
Empirical Evidence of Associations Between Trial Quality and Effect Size (June 2011)
Addressing Challenges in Genetic Test Evaluation: Evaluation Frameworks and Assessment of Analytic Validity (June 2011)
Identifying Signals for Updating Systematic Reviews: A Comparison of Two Methods (June 2011)
Systematic Reviews of Diagnostic Tests (March 2011)
Development of Quality Criteria To Evaluate Nontherapeutic Studies of Incidence, Prevalence, or Risk Factors of Chronic Diseases: Pilot Study of New Checklists (February 2011)
Developing and Testing a Tool for the Classification of Study Designs in Systematic Reviews of Interventions and Exposures (January 2011)

Research White Papers

Developmental Disabilities Issues Exploration Forum: Cerebral Palsy (November 2011)
Stakeholder Involvement in Improving Comparative Effectiveness Reviews: AHRQ and the Effective Health Care Program (September 2011)
Identifying Priorities for Patient-Centered Outcomes Research for Serious Mental Illness (September 2011)

Methods Research on Future Research Needs Papers

Frameworks for Determining Research Gaps During Systematic Reviews (August 2011)
Assessing the Impact of AHRQ Evidence-based Practice Center (EPC) Reports on Future Research (June 2011)
Minimal Modeling Approaches to Value of Information Analysis for Health Research (June 2011)
Evaluating the Potential Use of Modeling and Value-of-Information Analysis for Future Research Prioritization Within the Evidence-based Practice Center Program (June 2011)
Engaging Stakeholders To Identify and Prioritize Future Research Needs (June 2011)
Defining an Optimal Format for Presenting Research Needs (June 2011)

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2010

Systematic Reviews

Interventions to Prevent Falls in Older Adults: An Updated Systematic Review (December 2010)
Behavioral Counseling to Promote Physical Activity and a Healthful Diet to Prevent Cardiovascular Disease in Adults: Update of the Evidence for the U.S. Preventive Services Task Force (December 2010)
Management of Acute Otitis Media: Update (November 2010)
Alcohol Consumption and Cancer Risk: Understanding Possible Causal Mechanisms for Breast and Colorectal Cancers (November 2010)
Screening Adults for Bladder Cancer: Update of the 2004 Evidence Review for the US Preventive Services Task Force (October 2010)
Inhaled Nitric Oxide in Preterm Infants (October 2010)
Complementary and Alternative Therapies for Back Pain II (October 2010)
Effectiveness of Recombinant Human Growth Hormone (rhGH) in the Treatment of Patients With Cystic Fibrosis (October 2010)
Bone Morphogenetic Protein: The State of the Evidence for On-Label and Off-Label Use (August 2010)
Radiation Therapy for Localized Prostate Cancer: An Update (August 2010)
Screening for Osteoporosis: Systematic Review to Update the 2002 U.S. Preventive Services Task Force Recommendation (July 2010)
Comparative Effectiveness of Nonoperative and Operative Treatments for Rotator Cuff Tears (July 2010)
Consideration of Evidence on Antiemetic Drugs for Nausea and Vomiting Associated with Chemotherapy or Radiation Therapy (July 2010)
Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications vs. Usual Care (June 2010)
Systematic Reviews on Selected Pharmacogenetic Tests for Cancer Treatment: CYP2D6 for Tamoxifen in Breast Cancer, KRAS for anti-EGFR antibodies in Colorectal Cancer, and BCR-ABL1 for Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia (June 2010)
Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer (May 2010)
Diagnosis and Treatment of Secondary Lymphedema (May 2010)
ECG-based Signal Analysis Technologies (May 2010)
Quality, Regulation and Clinical Utility of Laboratory-developed Molecular Tests (Corrected Final Report) (May 2010)
Alzheimer's Disease and Cognitive Decline (April 2010)
Vaginal Birth After Cesarean: New Insights (March 2010)
Genetic Tests for Non-Cancer Diseases/Conditions: A Horizon Scan (Updated) (March 2010)
A Systematic Review of Loss-of-Heterozygosity Based Topographic Genotyping with PathfinderTG® (March 2010)
Lactose Intolerance and Health (February 2010)
Enhancing Use and Quality of Colorectal Cancer Screening (February 2010)
Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-based Drugs (February 2010)
Exercise-induced Bronchoconstriction and Asthma (January 2010)
Report on the Evidence Regarding Off-Label Indications for Targeted Therapies used in Cancer Treatment (January 2010)
Effectiveness of Primary Care Interventions for Weight Management in Children and Adolescents (January 2010)

Technical Briefs

Vulnerable Atherosclerotic Plaque (August 2010) (Archived)
Percutaneous Heart Valve Replacement (August 2010) (Archived)

Methods Research Reports

Comparative Effectiveness Review Methods: Clinical Heterogeneity (September 2010)

Methods Research on Future Research Needs Papers

Finding Evidence on Ongoing Studies (December 2010)

Future Research Needs Papers

Future Research Needs for Angiotensin Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers Added to Standard Medical Therapy for Treating Stable Ischemic Heart Disease (November 2010)
Future Research Needs for the Management of Gestational Diabetes (November 2010)
Future Research Needs for Outcomes of Weight Gain in Pregnancy (November 2010)
Future Research Needs To Reduce the Risk of Primary Breast Cancer in Women (September 2010)
Future Research Needs for Comparative Effectiveness of Treatments of Localized Prostate Cancer (September 2010)
Future Research Needs for the Integration of Mental Health/Substance Abuse and Primary Care (September 2010)
Future Research Needs for the Treatment of Common Hip Fractures (September 2010)
Future Research Needs for the Comparison of Percutaneous Coronary Interventions With Bypass Graft Surgery in Nonacute Coronary Artery Disease (September 2010)

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2009

Systematic Reviews

Comparative Effectiveness of Core-Needle and Open Surgical Biopsy for the Diagnosis of Breast Lesions (December 2009)
Screening for Depression in Adults and Older Adults in Primary Care (December 2009)
Screening for Breast Cancer (November 2009)
Impact of Consumer Health Informatics Applications (October 2009)
Comparative Effectiveness of Angiotensin Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers Added to Standard Medical Therapy for Treating Stable Ischemic Heart Disease (October 2009)
Screening for Intermediate Risk Factors for Coronary Heart Disease (October 2009)
Screening for Bilirubin Encephalopathy (October 2009)
Use of Bayesian Techniques in Randomized Clinical Trials: A CMS Case Study (September 2009)
Comparative Effectiveness of Medications To Reduce Risk of Primary Breast Cancer in Women (September 2009)
Family History and Improving Health (September 2009)
Diagnosis and Management of Ductal Carcinoma in Situ (DCIS) (September 2009)
Comparative Effectiveness of Lipid-Modifying Agents (September 2009) (Archived)
Horizon Scan: To What Extent Do Changes In Third-Party Payment Affect Clinical Trials And The Evidence Base? (August 2009)
Treatment of Overactive Bladder in Women (August 2009)
Treatment of Common Hip Fractures (August 2009)
Vitamin D and Calcium: Systematic Review of Health Outcomes (August 2009) (Archived)
Screening for Visual Impairment in Older Adults (July 2009)
Outcomes of Community Health Worker Interventions (June 2009)
Outcomes of Genetic Testing in Adults with a History of Venous Thromboembolism (June 2009)
Diagnosis and Treatment of Erectile Dysfunction (May 2009)
Negative Pressure Wound Therapy Devices (May 2009) (Archived)
Folic Acid Supplementation for the Prevention of Neural Tube Defects (May 2009)
Screening for Child and Adolescent Depression In Primary Care Settings (April 2009)
White Paper: Potential Conflict of Interest in the Production of Drug Compendia (April 2009)
Clinical Utility of Cancer Family History Collection in Primary Care (April 2009)
Maternal and Neonatal Outcomes of Elective Induction of Labor (March 2009)
Aspirin for the Primary Prevention of Cardiovascular Events (March 2009)
Evaluating Test Strategies for Colorectal Cancer Screening—Age to Begin, Age to Stop, and Timing of Screening Intervals (March 2009)
Complementary and Alternative Medicine in Back Pain Utilization (January 2009)
Cost-Effectiveness of CT Colonography to Screen for Colorectal Cancer (January 2009)

Technical Briefs

Particle Beam Radiation Therapies for Cancer (September 2009) (Archived)

Research White Papers

Using the Principles of Randomized Controlled Trial Design To Guide Test Evaluation (November 2009)
Additional Patient Outcomes and Alternative Pathways in Evaluations of Testing (November 2009)
Decision-Analytic Modeling To Evaluate Benefits and Harms of Medical Tests—Uses and Limitations (November 2009)
Medical Tests—White Paper Series (November 2009)
Proposals for a Phased Evaluation of Medical Tests (November 2009)

Technical Reviews

Reporting of Systematic Reviews of Micronutrients and Health (March 2009)
Issues & Challenges in Conducting Systematic Reviews to Support Development of Nutrient Reference Values (March 2009)
Screening for Skin Cancer: An Update of the Evidence for the U.S. Preventive Services Task Force (February 2009)
Application of Systematic Review Methodology to the Field of Nutrition (January 2009)

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2008

Systematic Reviews

Comparative Effectiveness of Radiofrequency Catheter Ablation for Atrial Fibrillation (December 2008)
Reviews of Selected Pharmacogenetic Tests for Non-Cancer and Cancer Conditions (November 2008)
Barriers and Drivers of Health IT Use for the Elderly, Chronically Ill, and Underserved (November 2008)
HER2 Testing to Manage Patients with Breast or Other Solid Tumors (November 2008)
Bariatric Surgery in Women of Reproductive Age: Special Concerns for Pregnancy (November 2008)
Interventions in Primary Care to Promote Breastfeeding (October 2008)
Screening for Colorectal Cancer: An Updated Systematic Review (October 2008)
Behavioral Counseling to Prevent Sexually Transmitted Infections (October 2008)
Management of Chronic Hepatitis B (October 2008)
Integration of Mental Health/Substance Abuse and Primary Care (October 2008)
Effectiveness of Weight Management Programs in Children and Adolescents (September 2008)
Comparative Effectiveness, Safety, and Indications of Insulin Analogues in Premixed Formations for Adults With Type 2 Diabetes (September 2008) (Archived)
Benefits and Harms of Prostate-Specific Antigen Screening for Prostate Cancer (August 2008) (Archived)
Universal Newborn Hearing Screening: Systematic Review to Update the 2001 U.S. Preventive Services Task Force Recommendation (August 2008)
Screening for Type 2 Diabetes Mellitus: Update of 2003 Systematic Evidence Review for the U. S. Preventive Services Task Force (June 2008)
Screening for Lipid Disorders in Adults: Selective Update of 2001 U.S. Preventive Services Task Force Review (June 2008)
Screening for Gestational Diabetes Mellitus (May 2008)
Outcomes of Maternal Weight Gain (May 2008)
Effectiveness of Assisted Reproductive Technology (May 2008)
Diabetes Education for Children With Type 1 Diabetes Mellitus and Their Families (April 2008)
Therapeutic Management, Delivery, and Postpartum Risk Assessment and Screening in Gestational Diabetes (March 2008)
Screening for Chronic Obstructive Pulmonary Disease Using Spirometry (March 2008)
Hydroxyurea for the Treatment of Sickle Cell Disease (February 2008)
Utility of Monitoring Mycophenolic Acid in Solid Organ Transplant Patients (February 2008)
Carbohydrate and Lipid Disorders and Relevant Considerations in Persons with Spinal Cord Injury (February 2008)
Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer (February 2008)
Screening in Primary Care Settings for Illicit Drug Use: Assessment of Screening Instruments (January 2008)
Screening in Primary Care Settings for Illicit Drug Use: Staged Systematic Review for the United States Preventive Services Task Force (January 2008)
Screening and Treatment for Bacterial Vaginosis in Pregnancy: Systematic Review to Update the 2001 U.S. Preventive Services Task Force Recommendation (January 2008)
Impact of Gene Expression Profiling Tests on Breast Cancer Outcomes (January 2008) (Archived)

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2007

Systematic Reviews

Evidence for the Reaffirmation of the U.S. Preventive Services Task Force Recommendation on Screening for High Blood Pressure (December 2007)
Screening for Hemoglobinopathies in Newborns: Reaffirmation Update for the U.S. Preventive Services Task Force (December 2007)
Screening For Asymptomatic Carotid Artery Stenosis (December 2007)
Prevention of Fecal and Urinary Incontinence in Adults (December 2007) (Archived)
Comparative Effectiveness of Treatments To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis (December 2007) (Archived)
Comparative Effectiveness of Management Strategies for Renal Artery Stenosis: 2007 Update (November 2007)
Comparative Effectiveness of Drug Therapy for Rheumatoid Arthritis and Psoriatic Arthritis in Adults (November 2007) (Archived)
Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Antagonists for Treating Essential Hypertension (November 2007) (Archived)
Comparative Effectiveness of Percutaneous Coronary Interventions and Coronary Artery Bypass Grafting for Coronary Artery Disease (October 2007) (Archived)
Collection and Use of Cancer Family History in Primary Care (October 2007) (Archived)
Treatment of Primary and Secondary Osteoarthritis of the Knee (October 2007) (Archived)
Antiretroviral (ARV) Drug Resistance in the Developing World (September 2007) (Archived)
Primary Care Interventions to Prevent Motor Vehicle Occupant Injuries (August 2007)
Effectiveness and Safety of Vitamin D in Relation to Bone Health (August 2007) (Archived)
Comparative Effectiveness and Safety of Oral Diabetes Medications for Adults With Type 2 Diabetes (July 2007) (Archived)
Screening for Lipid Disorders in Children and Adolescents (July 2007)
Management of Uterine Fibroids: An Update of the Evidence (July 2007) (Archived)
Meditation Practices for Health: State of the Research (June 2007) (Archived)
Screening for Chlamydial Infection: A Focused Evidence Update for the U.S. Preventive Services Task Force (June 2007)
Breastfeeding and Maternal and Infant Health Outcomes in Developed Countries (April 2007) (Archived)
Screening for Human Immunodeficiency Virus (April 2007) (Archived)
Use of Aspirin and NSAIDs to Prevent Colorectal Cancer (March 2007)
Nurse Staffing and Quality of Patient Care (March 2007) (Archived)
Hereditary Nonpolyposis Colorectal Cancer: Diagnostic Strategies and Their Implications (May 2007) (Archived)
Effectiveness of Continuing Medical Education (February 2007) (Archived)
Comparative Effectiveness of Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression (January 2007) (Archived)
Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics (January 2007) (Archived)
Testing for Cytochrome P450 Polymorphisms in Adults With Non-Psychotic Depression Treated With Selective Serotonin Reuptake Inhibitors (SSRIs) (January 2007) (Archived)

Technical Reviews

Updating Systematic Reviews (September 2007)
Consumer-Oriented Strategies for Improving Health Benefit Design: An Overview (July 2007) (Archived)
A Critical Analysis of Care Coordination Strategies for Children With Special Health Care Needs (June 2007) (Archived)

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2006

Systematic Reviews

Screening for Elevated Lead Levels in Childhood and Pregnancy: Update of a 1996 U.S. Preventive Services Task Force Review (December 2006)
The Uses of Heparin To Treat Burn Injury (December 2006) (Archived)
The Effectiveness of Different Methods of Toilet Training for Bowel and Bladder Control (December 2006) (Archived)
Genomic Tests for Ovarian Cancer Detection and Management (October 2006) (Archived)
Testing for BNP and NT-proBNP in the Diagnosis and Prognosis of Heart Failure (September 2006) (Archived)
Comparative Effectiveness and Safety of Analgesics for Osteoarthritis (September 2006) (Archived)
Screening for Hereditary Hemochromatosis (August 2006)
Pediatric Anthrax: Implications for Bioterrorism Preparedness (August 2006) (Archived)
Comparison of Endovascular and Open Surgical Repairs for Abdominal Aortic Aneurysm (August 2006) (Archived)
Management of Small Cell Lung Cancer (July 2006) (Archived)
Tobacco Use: Prevention, Cessation, and Control (June 2006) (Archived)
Multivitamin/Mineral Supplements and Prevention of Chronic Disease (May 2006) (Archived)
Cancer Care Quality Measures: Diagnosis and Treatment of Colorectal Cancer (May 2006) (Archived)
Cancer Care Quality Measures: Symptoms and End of Life Care (May 2006) (Archived)
Comparative Effectiveness of Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment (May 2006) (Archived)
Value of the Periodic Health Evaluation (April 2006) (Archived)
Management of Eating Disorders (April 2006) (Archived)
B Vitamins and Berries and Age-Related Neurodegenerative Disorders (April 2006) (Archived)
Costs and Benefits of Health Information Technology (April 2006) (Archived)
Screening for Iron Deficiency Anemia in Childhood and Pregnancy (April 2006)
Cesarean Delivery on Maternal Request (March 2006) (Archived)
Screening for Developmental Dysplasia of the Hip (March 2006)
Screening for Speech and Language Delay in Preschool Children (February 2006)
Management of Adnexal Mass (February 2006) (Archived)
Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities (February 2006) (Archived)
Telemedicine for the Medicare Population—Update (January 2006) (Archived)

Technical Reviews

Empirical Evaluation of the Association Between Methodological Shortcomings and Estimates of Adverse Events (October 2006)
Criteria for Distinguishing Effectiveness From Efficacy Trials in Systematic Reviews (April 2006) 
Developing a Methodology for Establishing a Statement of Work for a Policy-Relevant Technical Analysis (January 2006) (Archived)

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2005

Systematic Reviews

Comparative Effectiveness of Management Strategies for Gastroesophageal Reflux Disease (December 2005) (Archived)
Diagnosis and Management of Work-Related Asthma (October 2005) (Archived)
Diagnosis, Prognosis, and Therapy of Impaired Glucose Tolerance and Impaired Fasting Glucose (September 2005) (Archived)
Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility (September 2005) (Archived)
Effects of Soy on Health Outcomes (August 2005) (Archived)
Use of Spirometry for Case Finding, Diagnosis, and Management of Chronic Obstructive Pulmonary Disease (COPD) (August 2005) (Archived)
Effects of Omega-3 Fatty Acids on Child and Maternal Health (August 2005) (Archived)
Effects of Omega-3 Fatty Acids on Eye Health (July 2005) (Archived)
Effects of Omega-3 Fatty Acids on Mental Health (July 2005) (Archived)
Acute Stroke: Evaluation and Treatment (July 2005) (Archived)
Screening for Human Immunodeficiency Virus in Pregnant Women (July 2005) (Archived)
Screening for Human Immunodeficiency Virus in Adolescents and Adults (July 2005) (Archived)
Screening and Interventions for Childhood Overweight (July 2005) (Archived)
Knowledge and Access to Information on Recruitment of Underrepresented Populations to Cancer Clinical Trials (June 2005) (Archived)
Manifestations and Management of Chronic Insomnia in Adults (June 2005) (Archived)
Update on Acute Bacterial Rhinosinusitis (June 2005) (Archived)
The Use of Episiotomy in Obstetrical Care: A Systematic Review (May 2005) (Archived
Post-Myocardial Infarction Depression (May 2005) (Archived)
Management of Menopause-Related Symptoms (March 2005) (Archived)
Primary Care Screening for Ocular Hypertension and Primary Open-Angle Glaucoma (March 2005) (Archived)
Effects of Omega-3 Fatty Acids on Organ Transplantation (February 2005) (Archived)
Effects of Omega-3 Fatty Acids on Cognitive Function with Aging, Dementia, and Neurological Diseases (February 2005) (Archived)
Perinatal Depression: Prevalence, Screening Accuracy, and Screening Outcomes (February 2005) (Archived)
Effects of Omega-3 Fatty Acids on Cancer (February 2005) (Archived)
Primary Care Screening for Abdominal Aortic Aneurysm (February 2005) (Archived)

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2004

Systematic Reviews

 

Wound-Healing Technologies: Low-Level Laser and Vacuum-Assisted Closure (December 2004) (Archived)Sexuality and Reproductive Health Following Spinal Cord Injury (December 2004) (Archived)
Cardiac Resynchronization Therapy and Implantable Cardiac Defibrillators in Left Ventricular Systolic Dysfunction (November 2004) (Archived)
End-of-Life Care and Outcomes (November 2004) (Archived)
Melatonin for Treatment of Sleep Disorders (November 2004) (Archived)
Preventing Violence and Related Health-Risking Social Behaviors in Adolescents (October 2004) (Archived)
Measuring the Quality of Breast Cancer Care in Women (September 2004) (Archived)
Economic Incentives for Preventive Care (August 2004) (Archived)
Community-Based Participatory Research (August 2004) (Archived)
Islet Transplantation in Patients with Type 1 Diabetes Mellitus (July 2004) (Archived)
Pharmacological and Surgical Treatment of Obesity (July 2004) (Archived)
Celiac Disease (June 2004) (Archived)
Effectiveness of Behavioral Interventions to Modify Physical Activity Behaviors in General Populations and Cancer Patients and Survivors (June 2004) (Archived)
Criteria to Determine Disability Related to Multiple Sclerosis (May 2004) (Archived)
Screening for Suicide Risk (May 2004) (Archived)
Lung Cancer Screening (May 2004) (Archived)
Screening for Visual Impairment in Children Younger than Age 5 Years (May 2004) (Archived)
Pharmacological Treatment of Dementia (April 2004) (Archived)
Regionalization of Bioterrorism Preparedness and Response (April 2004) (Archived)
Training of Hospital Staff To Respond to a Mass Casualty Incident (April 2004) (Archived)
Effects of Omega-3 Fatty Acids on Cardiovascular Disease (March 2004) (Archived)
Effects of Omega-3 Fatty Acids on Cardiovascular Risk Factors and Intermediate Markers of Cardiovascular Disease (March 2004) (Archived)
Effects of Omega-3 Fatty Acids on Arrhythmogenic Mechanisms in Animal and Isolated Organ/Cell Culture Studies (March 2004) (Archived)
Health Effects of Omega-3 Fatty Acids on Asthma (March 2004) (Archived)
Effects of Omega-3 Fatty Acids on Lipids and Glycemic Control in Type II Diabetes and the Metabolic Syndrome and on Inflammatory Bowel Disease, Rheumatoid Arthritis, Renal Disease, Systemic Lupus Erythematosus, and Osteoporosis (March 2004) (Archived)
Behavioral Counseling Interventions in Primary Care to Reduce Risky/Harmful Alcohol Use (March 2004) (Archived)
Dental Caries Prevention (March 2004) (Archived)
Screening for Family and Intimate Partner Violence (March 2004) (Archived)
Screening for Hepatitis C Virus Infection (March 2004) (Archived)
Screening for Thyroid Disease (January 2004) (Archived)
Effectiveness of Antimicrobial Adjuncts to Scaling and Root-Planing Therapy for Periodontitis (January 2004) (Archived)
Literacy and Health Outcomes (January 2004) (Archived)
Strategies for Improving Minority Healthcare Quality (January 2004) (Archived)
 

Technical Reviews

 

Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies (August 2004–June 2007)

Quality-based Purchasing, Support Strategies (July 2004)
Meta-Regression Approaches: What, Why, When, and How? (March 2004) Top of Page

2003

Systematic Reviews

Screening for Asymptomatic Coronary Artery Disease (December 2003) (Archived)
Screening and Interventions for Overweight and Obesity in Adults (December 2003) (Archived)
Total Knee Replacement (Archived) (December 2003)
Hyperbaric Oxygen Therapy for Brain Injury, Cerebral Palsy, and Stroke (September 2003) (Archived)
Effect of the Supplemental Use of Antioxidants Vitamin C, Vitamin E, and the Coenzyme Q10 for the Prevention and Treatment of Cancer (August 2003) (Archived)
Use of Glycated Hemoglobin and Microalbuminuria in the Monitoring of Diabetes Mellitus (July 2003) (Archived)
Effect of Supplemental Antioxidants Vitamin C, Vitamin E, and Coenzyme Q10 for the Prevention and Treatment of Cardiovascular Disease (July 2003) (Archived)
Pharmacologic Management of Heart Failure and Left Ventricular Systolic Dysfunction: Effect in Female, Black, and Diabetic Patients, and Cost-Effectiveness (July 2003) (Archived)
Diagnosis and Treatment of Parkinson's Disease: A Systematic Review of the Literature (June 2003) (Archived)
Surgical Treatment of Coexisting Cataract and Glaucoma (June 2003) (Archived)
Screening for Dementia (June 2003)
Diagnosis and Treatment of Coronary Heart Disease in Women: Systematic Reviews of Evidence on Selected Topics (May 2003) (Archived)
Results of Systematic Review of Research on Diagnosis and Treatment of Coronary Heart Disease in Women (May 2003) (Archived)
Diffusion and Dissemination of Evidence-based Cancer Control Interventions (May 2003) (Archived)
Best-Case Series for the Use of Immuno-Augmentation Therapy and Naltrexone for the Treatment of Cancer (April 2003) (Archived)
Management of Treatment-Resistant Epilepsy (April 2003) (Archived)
Ephedra and Ephedrine for Weight Loss and Athletic Performance Enhancement: Clinical Efficacy and Side Effects (March 2003) (Archived)
The Effect of Health Care Working Conditions on Patient Safety (March 2003) (Archived)
Criteria for Determining Disability in Infants and Children: Short Stature (March 2003) (Archived)
Criteria for Determining Disability in Infants and Children: Failure to Thrive (March 2003) (Archived)
Vaginal Birth After Cesarean (VBAC) (March 2003) (Archived)
Criteria for Determining Disability in Infants and Children: Low Birth Weight (March 2003) (Archived)
Screening for Type 2 Diabetes Mellitus (February 2003) (Archived)
Management of Allergic Rhinitis in the Working-Age Population (February 2003) (Archived)
Screening for Gestational Diabetes Mellitus (February 2003) (Archived)
Management of Bronchiolitis in Infants and Children (January 2003) (Archived)
Diagnosis and Treatment of Deep Venous Thrombosis and Pulmonary Embolism (January 2003) (Archived)

Technical Reviews

Determinants of Increases in Medicare Expenditures for Physicians' Services (October 2003)

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2002

Systematic Reviews

 

Systematic Review of the Current Literature Related to Disability and Chronic Fatigue Syndrome (December 2002) (Archived)
Management of Neonatal Hyperbilirubinemia (November 2002) (Archived)
Utility of Blood Pressure Monitoring Outside of the Clinic Setting (November 2002) (Archived)
Diagnosis and Treatment of Worker-Related Musculoskeletal Disorders of the Upper Extremity (October 2002) (Archived)
Autopsy as Outcome and Performance Measure (October 2002) (Archived)
Screening for Prostate Cancer (October 2002) (Archived)
Screening for Postmenopausal Osteoporosis (September 2002) (Archived)
S-Adenosyl-L-Methionine (SAMe) for Depression, Osteoarthritis, and Liver Disease (August 2002) (Archived)
Screening for Breast Cancer (August 2002) (Archived)
Hormone Replacement Therapy and Breast Cancer (August 2002) (Archived)
Hormone Replacement Therapy and Cognition (August 2002) (Archived)
Hormone Replacement Therapy and Osteoporosis (August 2002) (Archived)
Hormone Replacement Therapy and Risk of Venous Thromboembolism (August 2002) (Archived)
Postmenopausal Hormone Replacement Therapy and Cardiovascular Disease (August 2002) (Archived)
Clinician Counseling to Promote Physical Activity (August 2002) (Archived)
Chemoprevention of Breast Cancer (July 2002) (Archived)
Screening for Colorectal Cancer in Adults (July 2002) (Archived)
Management of Cancer Symptoms: Pain, Depression, and Fatigue (July 2002) (Archived)
Effectiveness and Cost-Effectiveness of Echocardiography and Carotid Imaging in the Management of Stroke (July 2002) (Archived)
Impact of Cancer-Related Decision Aids (July 2002) (Archived)
Cardiovascular Effects of Epinephrine in Hypertensive Dental Patients (July 2002) (Archived)
Management of Chronic Hepatitis C (June 2002) (Archived)
Bioterrorism Preparedness and Response: Use of Information Technologies and Decision Support Systems (June 2002) (Archived)
Diagnosis, Natural History, and Late Effects of Otitis Media with Effusion (June 2002) (Archived)
Endoscopic Retrograde Cholangiopancreatography (June 2002) (Archived)
Management of Allergic and Nonallergic Rhinitis (May 2002) (Archived)
Screening for Depression (April 2002) (Archived)
Counseling to Promote a Healthy Diet (April 2002) (Archived)
Management of Prolonged Pregnancy (March 2002) (Archived)
Systems to Rate the Strength of Scientific Evidence (March 2002) (Archived)
Management of Clinically Inapparent Adrenal Mass (February 2002) (Archived)
Criteria for Determining Disability in Speech-Language Disorders (January 2002) (Archived)
Screening for Cervical Cancer (January 2002) (Archived)

Technical Reviews

Current Validity of AHRQ Clinical Practice Guidelines (September 2002) (Archived)
Patient Safety Indicators: Hospital Data (August 2002)

Top of Page

2001

Systematic Reviews

Training Clinicians for Public Health Events Relevant to Bioterrorism Preparedness (December 2001) (Archived)
Newborn Hearing Screening (October 2001) (Archived)
Management of Chronic Neuropathic Pain Following Traumatic Spinal Cord Injury (September 2001) (Archived)
Management of Chronic Asthma (September 2001) (Archived)
Defining and Managing Chronic Fatigue Syndrome (September 2001) (Archived)
Management of Acne (September 2001) (Archived)
Telemedicine for the Medicare Population: Pediatric, Obstetric, and Clinician-Indirect Home Interventions (Supplement) (August 2001) (Archived)
Making Health Care Safer: A Critical Analysis of Patient Safety Practices (July 2001) (Archived)
Telemedicine for the Medicare Population (July 2001) (Archived)
Ayurvedic Interventions for Diabetes Mellitus: A Systematic Review (June 2001) (Archived)
Treatment of Pulmonary Disease Following Cervical Spinal Cord Injury (June 2001) (Archived)
Diagnosis and Management of Specific Breast Abnormalities (April 2001) (Archived)
Screening for Lipid Disorders (April 2001) (Archived)
Screening for Chlamydial Infection (April 2001) (Archived)
Screening for Skin Cancer (April 2001) (Archived)
Screening for Bacterial Vaginosis in Pregnancy (April 2001) (Archived)
Mind-Body Interventions for Gastrointestinal Conditions (March 2001) (Archived)
Treatment of Degenerative Lumbar Spinal Stenosis (March 2001) (Archived)
Uses of Epoetin for Anemia in Oncology (March 2001) (Archived)
Use of Epoetin for Anemia in Chronic Renal Failure (March 2001) (Archived)
Osteoporosis in Postmenopausal Women: Diagnosis and Monitoring (February 2001) (Archived)
Management of Newly Diagnosed Patients with Epilepsy: A Systematic Review of the Literature (February 2001) (Archived)
Management of Dental Patients Who Are HIV Positive (February 2001) (Archived)
Diagnosis and Management of Dental Caries (February 2001) (Archived)
Management of Cancer Pain (January 2001) (Archived)
Management of Uterine Fibroids (January 2001) (Archived)
 

Technical Reviews

Refinement of the HCUP Quality Indicators (May 2001) (Archived)

Top of Page

2000

Systematic Reviews

 

Prediction of Risk for Patients with Unstable Angina (December 2000) (Archived)
Management of Preterm Labor (December 2000) (Archived)
Efficacy of Interventions to Modify Dietary Behavior Related to Cancer Risk (November 2000) (Archived)
Diagnosis and Treatment of Uncomplicated Acute Sinusitis in Children (Supplement) (October 2000) (Archived)
Garlic: Effects on Cardiovascular Risks and Disease, Protective Effects Against Cancer, and Clinical Adverse Effects (October 2000) (Archived)
Management of Acute Exacerbations of Chronic Obstructive Pulmonary Disease (September 2000) (Archived)
Evaluation of Technologies for Identification of Acute Cardiac Ischemia in the Emergency Department (September 2000) (Archived)
Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical Adverse Effects (September 2000) (Archived)
Prevention of Venous Thromboembolism After Injury (August 2000) (Archived)
Management of Chronic Hypertension During Pregnancy (August 2000) (Archived)
Anesthesia Management During Cataract Surgery (July 2000) (Archived)
Criteria for Weaning From Mechanical Ventilation (June 2000) (Archived)
Management of Acute Otitis Media (June 2000) (Archived)
Determinants of Disability in Patients with Chronic Renal Failure (May 2000) (Archived)
Management of New Onset Atrial Fibrillation (May 2000) (Archived)

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1999

Systematic Reviews

 

Treatment of Attention-Deficit/Hyperactivity Disorder (November 1999) (Archived)
An Evaluation of Beta-Blockers, Calcium Antagonists, Nitrates, and Alternative Therapies for Stable Angina (November 1999) (Archived)
Diagnosis and Treatment of Acute Bacterial Rhinosinusitis (October 1999) (Archived)
Rehabilitation for Traumatic Brain Injury in Children and Adolescents (Supplement) (September 1999) (Archived)
Diagnosis and Treatment of Swallowing Disorders (Dysphagia) in Acute-Care Stroke Patients (March 1999) (Archived)
Treatment of Depression—Newer Pharmacotherapies (March 1999) (Archived)
Prevention and Management of Urinary Tract Infections in Paralyzed Persons (January 1999) (Archived)
Evaluation of Cervical Cytology (January 1999) (Archived)
Relative Effectiveness and Cost-Effectiveness of Methods of Androgen Suppression in the Treatment of Advanced Prostatic Cancer (January 1999) (Archived)
Pharmacotherapy for Alcohol Dependence (January 1999) (Archived)
 

Technical Reviews

 

Diagnosis of Attention Deficit/Hyperactivity Disorder (August 1999) (Archived)

Headache, Treatment (February 1999) (Archived)

  • Chronic Headache
  • Migraine Headache, Behavioral and Physical Treatments
  • Migraine Headache, Drug Treatments
  • Acute Migraine Headache, Self-Administered Drug Treatments
  • Acute Migraine Headache, Parenteral Drug Treatments
Top of Page

1998

Technical Reviews

Rehabilitation for Traumatic Brain Injury (December 1998) (Archived)
Systematic Review of the Literature Regarding the Diagnosis of Sleep Apnea (December 1998) (Archived)
Colorectal Cancer Screening (May 1998) (Archived)

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