Figure 1. Percent patients suffering selected injuries commonly studied among patients who experienced adverse drug events (Text Description)

Reducing and Preventing Adverse Drug Events To Decrease Hospital Costs

Study: Leape LL, Brennan TA, Laird N, et al. The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. N Engl J Med 1991;324(6):377-84

Cardiac: 9.6%
Gastrointestinal: 7.9%
Central nervous system: 14.6%
Allergic reaction: 14.0%
Renal distress: 6.7%
Bleeding: 14.6%

Study: Classen DC, Pestotnik SL, Evans RS, et al. Adverse drug events in hospitalized patients. JAMA 1997;277(4):301-6.

Cardiac: 25.7%
Gastrointestinal: 28.6%
Central nervous system: 4.0%
Allergic reaction: 26.5%
Renal distress: 13.1%
Bleeding: 1.1%

Study: Jha AK, Kuperman GJ, Teich JM, et al. Identifying adverse drug events: development of a computer-based monitor and comparison with chart review and stimulated voluntary report. J Am Med Inform Assoc 1998;5(3):305-14.

Cardiac: 13.8%
Gastrointestinal: 13.1%
Central nervous system: 20.3%
Allergic reaction: 16.5%
Renal distress: 5.2%
Bleeding: 5.5%

Study: Bates DW, Spell N, Cullen DJ, et al. The costs of adverse drug events in hospitalized patients. JAMA 1997;277(4):307-11.

Cardiac: 16.0%
Gastrointestinal: 18.0%
Central nervous system: 18.0%
Allergic reaction: 16.0%

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