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Table 6. Two methods for assessing the strength of evidence

Assessing the Evidence for Context-Sensitive Effectiveness and Safety

GRADEAHRQ EPC Program
High = Further research is very unlikely to change our confidence on the estimate of effect.High + High confidence that the evidence reflects the true effect. Further research is very unlikely to change our confidence in the estimate of effect.
Moderate = Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.Moderate = Moderate confidence that the evidence reflects the true effect. Further research may change our confidence in the estimate of effect and may change the estimate.
Low = Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.Low� = Low confidence that the evidence reflects the true effect. Further research is likely to change our confidence in the estimate of effect and is likely to change the estimate.
Very Low = Any estimate of effect is very uncertain.Insufficient = Evidence either is unavailable or does not permit a conclusion.

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Current as of December 2010
Internet Citation: Table 6. Two methods for assessing the strength of evidence: Assessing the Evidence for Context-Sensitive Effectiveness and Safety . December 2010. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/research/findings/final-reports/contextsensitive/contexttab6.html