Appendix C

Technology Assessment: Non-Pharmacological Interventions for Post-Disc

Technology assessment on the effectiveness of non-pharmacological interventions for post-discharge care in heart failure patients.

Table of Contents

Appendix C

C1a. Cost among patients with interventions beginning inpatient versus control

AuthorYearCountryCentersIntervention yN patientsFollowup monthsQualityN-InterventionCost_
Intervention
N_
Control
Cost_
Control
Net
Diff
P-ValueComments
Naylor2004USAM1997-0123912 118763612112481 0.002US Dollars
Koelling2005USAS2001-022236 10753691168292-28230.035US Dollars
Capomolla2002ItalyS 23412 11222441222409  Euros
Kasper2002USAM1996-982006 10216182988789 NSUS Dollars
Laramee2003USAS1999-002873 1412305414625536 NSUS Dollars
Cline1998SwedenS1991-319012 8022941103594 NSUS Dollars (cost in survivors)
Stewart1998AustraliaSnd976 493200485400 NSAustralian Dollar
Atienza2004SpainM 33816A16429121745417-2505 Euros
Del Sindaco2007ItalyM2001-021736 86149660.287248372.3-98712.1 Euros
Barth2001USASnd343 17401.8117124.68  US Dollars
Rich1995USAS1988-89983 63 35 -460 US Dollars (per patient per month = - $153)
McDonald2002UKS1998-00983 5199744747190-37216 Euros

C1b. Combined endpoints of mortality or readmission in the intervention beginning inpatient compared with control group

AuthorYearN patientsFollowup monthsN-InterventionsCombined eventsN ControlCombined eventsRRP-Value Primary endpoint
Del Sindaco20071736864087560.36<0.001RRR 0.167-0.509yes
Ledwidge2005130362468120.370.04OR = 0.07-0.84yes
Atienza2004338161640.71741.170.47<0.01Patient per yearyes
Stewart1998976490.8481.40.560.03Patient per yearyes
Koelling2005223610750116740.650.0180.45-0.93yes
Kasper200220061025098720.67NSP=0.03, Poisson modelyes
Dunagan200515112765375570.69ns0.47-1.01No
Linne2006230612258108550.93ns yes
Cline1998190128056110790.97NS No
Nucifora200620069995101901.08NS yes

C2a. Cost incurred among interventions post discharge versus control group

AuthorYearCountryN patientsFollowup monthsN-InterventionCost interventionN controlCost controlDifferenceP-ValueComments
Stewart1999Australia2006100490300100922600-432300.00nsAustralian $
Krumholz2002USA881244144204421935-7515.000.02 
Riegel2006USA134669100156913967-3952.00nd 
Morcillo2005Spain70634314.8361505.6-1190.80<.001Euro
Riegel2002USA358613011922282186-994.00nsInpatient Heart failure cost
Jerant2001   122888812215957293.00nsGroup telesupport vs usual care
Jerant2001USA376132970112215958106.00nsHome telecare vs usual care
Benatar2003USA21612108677710108500343177367.00nsHome Nurse Visit vs. Nurse telemanagement

C2b. Combined endpoints of mortality or death among interventions post discharge versus control group

AuthorYearFollowup monthsN-InterventionCombEvents InterventionN ControlCombEvents ControlRRP-ValueQuality
Thompson20056581548210.59ndC
Stewart19996100771001290.600.02A
Krumholz200212442544360.690.01B
Stromberg200312522954400.750.03A
Doughty2002121006897611.08nsC

C3. Combined end points and costs incurred in patients beginning intervention in the outpatient clinic versus control group

AuthorYearCountryCentersIntervention yN patientsFollowup monthsN-Interventioncombined_
Intervention
N_
Control
combined_
Control
RRP-ValueComments
Sisk2006USAM2000-0240612203 203 #DIV/0!  
GESICA2005ArgentinaM2000-011518167602997583390.880.057 
Bouvy2003NetherlandsM1998-001526741978191.05ns 
Murray2007USAM2001-0431412122 192 #DIV/0! Mean Difference - $2960 per patient (-$7603 to $1388)
Page last reviewed August 2014
Internet Citation: Appendix C: Technology Assessment: Non-Pharmacological Interventions for Post-Disc. August 2014. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/research/findings/ta/heart-failure-discharge-care/appendix-c.html