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Table 4.5. Postexposure Prophylaxis for Anthrax

Patient

Prophylactic Treatment

Adults (including pregnant women and immunocompromised people)

Ciprofloxacin 500 mg, PO, BID × 60 days or Doxycycline 100 mg, PO, BID × 60 days

Children

Ciprofloxacin 10-5 mg/kg, PO, BID × 60 days (total daily dose not to exceed 1000 mg) or Doxycycline at:

  • >8 yr and >45 kg: 100 mg, PO, BID × 60 days.
  • >8 yr and <45 kg: 2.2 mg/kg, PO, BID × 60 days.
  • 8 yr or younger: 2.2 mg/kg, PO, BID × 60 days.

Notes: BID = twice a day; PO = by mouth.

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