|
Drug |
Dosage |
|---|---|
|
Preferred choices |
|
|
Streptomycin |
15 mg/kg, IM, BID × 10 days (should not exceed 2 gram/day) |
|
Gentamicin |
2.5 mg/kg, IM or IV, TID × 10 days (not an FDA-approved use) |
|
Alternative choices |
|
|
Doxycyclinea |
If weight ≥45 kg, 100 mg, IV × 14-21 days |
|
If weight <45 kg, give 2.2 mg/kg, IV, BID × 14-21 days |
|
|
Chloramphenicola |
15 mg/kg, IV, 4 times daily × 14-21 days (not an FDA-approved use) |
|
Ciprofloxacina |
15 mg/kg, IV, BID × 10 days (should not exceed 1 gram/day) |
Notes: BID = twice a day; TID = three times a day; PO = by mouth; IV = intravenous; IM = intramuscular; FDA = Food and Drug Administration.
a Treatment with doxycycline, chloramphenicol, or ciprofloxacin given IM or IV can be switched to oral administration when clinically indicated.