Pediatric Terrorism and Disaster Preparedness: Table 4.6

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Drug	Dosage
*Preferred choices*
Streptomycin	15 mg/kg, IM, BID × 10 days (should not exceed 2 gram/day)
Gentamicin	2.5 mg/kg, IM or IV, TID × 10 days (not an FDA-approved use)
*Alternative choices*
Doxycycline^a	If weight ≥45 kg, 100 mg, IV × 14-21 days
Doxycycline^a	If weight <45 kg, give 2.2 mg/kg, IV, BID × 14-21 days
Chloramphenicol^a	15 mg/kg, IV, 4 times daily × 14-21 days (not an FDA-approved use)
Ciprofloxacin^a	15 mg/kg, IV, BID × 10 days (should not exceed 1 gram/day)

Notes: BID = twice a day; TID = three times a day; PO = by mouth; IV = intravenous; IM = intramuscular; FDA = Food and Drug Administration.

^a Treatment with doxycycline, chloramphenicol, or ciprofloxacin given IM or IV can be switched to oral administration when clinically indicated.