125. Treatment Recommendations: Medications (Continued)

Treating Tobacco Use and Dependence: 2008 Update

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Clinical guidelines for prescribing medication for treating tobacco use and dependence (Continued)

Are there contraindications, warnings, precautions, other concerns, and side effects regarding the first-line medications recommended in this Guideline Update? All seven FDA-approved medications have specific contraindications, warnings, precautions, other concerns, and side effects. Please refer to FDA package inserts for this complete information and FDA updates.
What other factors may influence medication selection? Pragmatic factors may also influence selection such as insurance coverage or out of pocket patient costs, likelihood of adherence, dentures when considering the gum, or dermatitis when considering the patch.
Is a patient's prior experience with a medication relevant? Prior successful experience (sustained abstinence with the medication) suggests that the medication may be helpful to the patient in a subsequent quit attempt, especially if the patient found the medication to be tolerable and/or easy to use. However, it is difficult to draw firm conclusions from prior failure with a medication. Some evidence suggests that retreating relapsed smokers with the same medication produces small or no benefit while other evidence suggests that it may be of substantial benefit.

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Page last reviewed October 2014
Page originally created September 2012
Internet Citation: 125. Treatment Recommendations: Medications (Continued). Content last reviewed October 2014. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/professionals/clinicians-providers/guidelines-recommendations/tobacco/clinicians/presentations/2008update-full/slide125.html