Related Content

Research Findings

AHRQ Research Studies

Sign up: mail-updates-icon AHRQ Research Studies Email updates

Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.

Oates GR, Phillips JM, Bateman LB
Determinants of obesity in two urban communities: perceptions and community-driven solutions.
Using Photovoice methodology, this study aimed to identify community perceptions of factors associated with obesity in two urban municipalities - one racially mixed and one predominantly African American - and to explore community-driven solutions to the problem of obesity.
Ethn Dis 2018 Winter;28(1):33-42. doi: 10.18865/ed.28.1.33.
AHRQ-funded; HS023009.
View abstract on the National Library of Medicine site.
Keywords: Obesity, Racial / Ethnic Minorities, Urban Health
Wilkinson ST, Kiselycznyk C, Banasr M
Serum and plasma brain-derived neurotrophic factor and response in a randomized controlled trial of riluzole for treatment resistant depression.
In this paper, the authors report serum brain-derived neurotrophic factor (BDNF) and plasma BDNF levels from a randomized controlled, adjunctive, sequential parallel comparison design trial of riluzole in major depressive disorder. The investigators noted that preliminary evidence suggested that lower baseline BDNF may be associated with better clinical response to riluzole.
J Affect Disord 2018 Dec 1;241:514-18. doi: 10.1016/j.jad.2018.08.075.
AHRQ-funded; HS023000.
View abstract on the National Library of Medicine site.
Keywords: Comparative Effectiveness, Depression, Medication, Patient-Centered Outcomes Research
Spatz ES
Fostering a culture to support surgical outcome measures.
This editorial comments on the relationship of surgical skills (referring to the gentleness, tissue exposure, instrument handling, time and motion, and flow of operation) and patient outcomes
Circ Cardiovasc Qual Outcomes 2016 Jul;9(4):345-7. doi: 10.1161/circoutcomes.116.003038.
AHRQ-funded; HS023000.
View abstract on the National Library of Medicine site.
Keywords: Outcomes, Provider Performance, Quality Measurement, Surgery
Silbverberg JI, Kantor RW, Dalal P
A comprehensive conceptual model of the experience of chronic itch in adults.
This study sought to develop a comprehensive conceptual model of itch to improve the understanding of itch for clinicians and to serve as a framework for development of efficient and valid patient-reported outcome measures (PROMs) of itch. The study’s conceptual model demonstrated the profound patient-burden of itch and identified unmet needs in the evaluation and management of itch.
Am J Clin Dermatol 2018 Oct;19(5):759-69. doi: 10.1007/s40257-018-0381-6.
AHRQ-funded; HS023011.
View abstract on the National Library of Medicine site.
Keywords: Chronic Care, Chronic Conditions, Patient Experience
Oates GR, Hamby BW, Bae S
Bikeshare use in urban communities: individual and neighborhood factors.
This study examined factors associated with bikeshare use in a metropolitan area in the southern United States. The study found that higher neighborhood socioeconomic disadvantage was associated with higher bikeshare use. Bikeshare was a viable transportation option in low-resource neighborhoods and may be an effective tool to improve the connectivity, livability, and health of urban communities.
Ethn Dis 2017 Nov 9;27(Suppl 1):303-12. doi: 10.18865/ed.27.S1.303.
AHRQ-funded; HS023009.
View abstract on the National Library of Medicine site.
Keywords: Health Status, Socioeconomic Factors, Urban Health
Wheeler KK, Shi J, Xiang H
US pediatric trauma patient unplanned 30-day readmissions.
This study sought to determine readmission rates and risk factors for acutely injured pediatric trauma patients. The study found that overall, the readmission rate for pediatric trauma patients was low. Measures of injury severity, specifically length of stay, were most useful in identifying those who would benefit from targeted care coordination resources.
J Pediatr Surg 2018 Apr;53(4):765-70. doi: 10.1016/j.jpedsurg.2017.08.003.
AHRQ-funded; HS024263.
View abstract on the National Library of Medicine site.
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Pediatrics, Readmissions, Trauma
Brennan MB, Guihan M, Budiman-Mak E
Increasing SBP variability is associated with an increased risk of developing incident diabetic foot ulcers.
This study evaluated the relationship between increased systolic blood pressure (SBP) variability and risk of incident diabetic foot ulceration using a nested case-control design. The investigators found a graded relationship between SBP variability and risk of diabetic foot ulceration, providing a potential new and modifiable target to reduce this common complication.
J Hypertens 2018 Nov;36(11):2177-84. doi: 10.1097/hjh.0000000000001783.
AHRQ-funded; HS018542.
View abstract on the National Library of Medicine site.
Keywords: Adverse Events, Diabetes, Risk Factors
Aalsma MC
Commentary on Border et al. (2018): the public health burden of conduct disorder, early mortality and criminal justice involvement.
This editorial comments on an article by Border et al. (2018), published in Addiction, entitled “Independent predictors of mortality in adolescents ascertained for conduct disorder and substance use problems, their siblings, and community controls."
Addiction 2018 Nov;113(11):2116-17. doi: 10.1111/add.14419.
AHRQ-funded; HS024296.
View abstract on the National Library of Medicine site.
Keywords: Behavioral Health, Children/Adolescents: Adolescents, Mortality, Public Health, Substance Abuse
Simpson LA, Koechlein L, Menachemi N
Show me the money! Trends in funding for health services research.
This paper presents longitudinal data representing federal funding for health services research and discusses the observed trends in the larger context of overall funding for research and development in the United States.
Health Serv Res 2018 Oct;53 Suppl 2:3967-75. doi: 10.1111/1475-6773.13040.
AHRQ-funded; 233201600155P.
View abstract on the National Library of Medicine site.
Keywords: Health Services Research (HSR)
Trinquart L, Dunn AG, Bourgeois FT
Registration of published randomized trials: a systematic review and meta-analysis.
The authors of this study aimed to determine the extent to which published randomized controlled trials (RCTs) were registered and registered prospectively. They found that the prevalence of trial registration increased over time, but only one in five published RCTs was prospectively registered, undermining the validity and integrity of biomedical research.
BMC Med 2018 Oct 16;16(1):173. doi: 10.1186/s12916-018-1168-6.
AHRQ-funded; HS024798.
View abstract on the National Library of Medicine site.
Keywords: Research, Research Methodologies
McManus KA, McManus K, Dillingham R
National survey of United States human immunodeficiency virus medical providers' knowledge and attitudes about the Affordable Care Act.
The objective of the study was to explore HIV medical providers' knowledge and attitudes about the Affordable Care Act (ACA). The investigators concluded that: medical providers in Medicaid expansion states were more optimistic about the ACA's likelihood to improve their patients' HIV outcomes; there are gaps in HIV medical providers' understanding of the ACA; and education could enhance systems-based practice.
Clin Infect Dis 2018 Oct 15;67(9):1403-10. doi: 10.1093/cid/ciy296.
AHRQ-funded; HS024196.
View abstract on the National Library of Medicine site.
Keywords: Health Reform, Human Immunodeficiency Virus (HIV), Medicaid, Provider
Moise N, Shah RN, Essock S
Sustainability of collaborative care management for depression in primary care settings with academic affiliations across New York State.
This study examined sustainability of collaborative care management for depression in primary care settings with academic affiliations across New York State. The investigators used descriptive statistics to assess implementation metrics in sustaining vs. opt-out clinics and trends in implementation fidelity 1 and 2 years into the sustainability phase among sustaining clinics.
Implement Sci 2018 Oct 12;13(1):128. doi: 10.1186/s13012-018-0818-6.
AHRQ-funded; HS025198
View abstract on the National Library of Medicine site.
Keywords: Collaborative Care, Depression, Mental Health, Primary Care
Rubio DM, Mayowski CA, Norman MK
A multi-pronged approach to diversifying the workforce.
This paper describes a multi-pronged, collaborative approach to enhance the diversity of trainees and scholars at the University of Pittsburgh Institute for Clinical Research Education. It describes the Career Education and Enhancement for Health Care Research Diversity (CEED) program, designed for postdoctoral fellows and junior faculty and the CEED II program designed for medical students.
Int J Environ Res Public Health 2018 Oct 11;15(10). doi: 10.3390/ijerph15102219.
AHRQ-funded; HS023185.
View abstract on the National Library of Medicine site.
Keywords: Education: Continuing Medical Education, Research, Training
Peltier WL, Gani F, Blissitt J
Initial experience with "Honoring Choices Wisconsin": implementation of an advance care planning pilot in a tertiary care setting.
The purpose of this study was to evaluate the impact of a pilot program using the "Honoring Choices Wisconsin" (HCW) model for advance care planning (ACP) in a tertiary care setting, and to understand barriers to system-wide implementation. The study concluded that implementation of a facilitator-based ACP care model was associated with fewer ICU admissions, and a higher use of hospice care.
J Palliat Med 2017 Sep;20(9):998-1003. doi: 10.1089/jpm.2016.0530.
AHRQ-funded; HS024736.
View abstract on the National Library of Medicine site.
Keywords: End-of-Life Care, Health Services Research (HSR), Palliative Care
Brennan-Cook J, Bonnabeau E, Aponte R
Barriers to care for persons with sickle cell disease: the case manager's opportunity to improve patient outcomes.
The purpose of this paper was to review the barriers to care for patients with sickle cell disease (SCD). Chronic pain and the perception of addiction, implicit bias, frequent hospitalizations and emergency department visits, clinician and patient knowledge deficits, and SCD stigma all impede the ability to provide evidence-based care for patients with SCD. The authors assert that case managers can coordinate and advocate for appropriate care that improves patient outcomes.
Prof Case Manag 2018 Jul/Aug;23(4):213-19. doi: 10.1097/ncm.0000000000000260.
AHRQ-funded; HS024501.
View abstract on the National Library of Medicine site.
Keywords: Access to Care, Healthcare: Delivery, Health Services Research (HSR), Patient-Centered Outcomes Research, Sickle Cell Disease
Bauer NS, Azer N, Sullivan PD
Acceptability of group visits for attention-deficit hyperactivity disorder in pediatric clinics.
The objective of the study was to describe the acceptability of ADHD group visits in busy pediatric clinics based on caregivers, child participants and facilitators. The authors found that the majority of comments from families and facilitators highlighted a variety of benefits of the use of a group visit model for ADHD chronic care. Despite systems-level barriers to implementation, families and facilitators felt the benefits outweighed the challenges.
J Dev Behav Pediatr 2017 Oct;38(8):565-72. doi: 10.1097/dbp.0000000000000492.
AHRQ-funded; HS022434.
View abstract on the National Library of Medicine site.
Keywords: Attention Deficit Hyperactivity Disorder (ADHD), Behavioral Health, Children/Adolescents, Mental Health, Patient-Centered Outcomes Research
Drucker AM, Adam GP, Rofeberg V
Treatments of primary basal cell carcinoma of the skin: a systematic review and network meta-analysis.
The purpose of the study was to evaluate the comparative effectiveness and safety of treatments of primary basal cell carcinoma (BCC) in adults. The investigators concluded that surgical treatments and external-beam radiation have low recurrence rates for the treatment of low-risk BCC, but substantial uncertainty exists about their comparative effectiveness versus other treatments. Gaps remain regarding high-risk BCC subtypes and important outcomes, including costs.
Ann Intern Med 2018 Oct 2;169(7):456-66. doi: 10.7326/m18-0678.
AHRQ-funded; 290201500002I.
View abstract on the National Library of Medicine site.
Keywords: Comparative Effectiveness, Evidence-based Medicine, Patient-Centered Outcomes Research, Cancer: Skin Cancer, Treatment Effectiveness
Chang S
Scoping reviews and systematic reviews: is it an either/or question?
This editorial comments on a paper by Tricco et al., (2018), published in the Annals of Internal Medicine and entitled “PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation.
Ann Intern Med 2018 Oct 2;169(7):502-03. doi: 10.7326/m18-2205.
AHRQ-authored.
View abstract on the National Library of Medicine site.
Keywords: Evidence-based Medicine, Research, Research Methodologies
Parrish KL, Hogan PG, Clemons AA
Spatial relationships among public places frequented by families plagued by methicillin-resistant Staphylococcus aureus.
In this study, the investigators mapped public places (including personal service establishments, fitness centers, pools, schools, and daycares) visited by members of households affected by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infection, in order to understand factors associated with CA-MRSA acquisition and infection.
BMC Res Notes 2018 Oct 1;11(1):692. doi: 10.1186/s13104-018-3797-4.
AHRQ-funded; HS024269; HS021736.
View abstract on the National Library of Medicine site.
Keywords: Community-Acquired Infections, Family Health and History, Methicillin-Resistant Staphylococcus aureus (MRSA)
Lee SC, Higashi RT, Sanders JM
Effects of program scale-up on time to resolution for patients with abnormal screening mammography results.
Effects of geographic program expansion to rural areas on mammogram screening program outcomes are understudied. The authors of this study sought to determine whether time-to-resolution (TTR) varied significantly by service delivery time period, location, and participant characteristics across 19 North Texas counties.
Cancer Causes Control 2018 Oct;29(10):995-1005. doi: 10.1007/s10552-018-1074-4.
AHRQ-funded; HS022418.
View abstract on the National Library of Medicine site.
Keywords: Cancer: Breast Cancer, Diagnosis, Imaging, Mammogram, Screening, Women's Health

Pages