National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
201 to 225 of 3101 Research Studies DisplayedViswanathan M, McPheeters ML, Murad MH
AHRQ series on complex intervention systematic reviews-paper 4: selecting analytic approaches.
This article addresses the uncertainty that systematic reviewers face in selecting methods for reviews of complex interventions. Specifically, it lays out parameters for systematic reviewers to consider when selecting analytic approaches that best answer the questions at hand and suggests analytic techniques that may be appropriate in different circumstances.
AHRQ-funded; 290201200004C.
Citation: Viswanathan M, McPheeters ML, Murad MH .
AHRQ series on complex intervention systematic reviews-paper 4: selecting analytic approaches.
J Clin Epidemiol 2017 Oct;90:28-36. doi: 10.1016/j.jclinepi.2017.06.014.
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Keywords: Data, Evidence-Based Practice, Guidelines, Research Methodologies
Pigott T, Noyes J, Umscheid CA
AHRQ series on complex intervention systematic reviews-paper 5: advanced analytic methods.
In this paper, the authors emphasize that the specific research question posed in the review should be used as a guide for choosing the appropriate analytic method. They present advanced analytic approaches that address some common questions that guide reviews of complex interventions such as: (1) How effective is the intervention? and (2) For whom does the intervention work and in what contexts?
AHRQ-funded; 290-2012-00004C; 290-2015-00005I; 290-2015-00004I; 290-2015-00009I; 290-2015-00013I; 290-2015-00011I; 290-2015-00003I.
Citation: Pigott T, Noyes J, Umscheid CA .
AHRQ series on complex intervention systematic reviews-paper 5: advanced analytic methods.
J Clin Epidemiol 2017 Oct;90:37-42. doi: 10.1016/j.jclinepi.2017.06.015.
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Keywords: Decision Making, Evidence-Based Practice, Guidelines, Research Methodologies
Guise JM, Butler ME, Chang C
AHRQ series on complex intervention systematic reviews-paper 6: PRISMA-CI extension statement and checklist.
This paper provides a stand-alone extension to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting tool for complex interventions-PRISMA-CI-to help authors, publishers, and readers understand and apply to systematic reviews of complex interventions. PRISMA-CI development followed the Enhancing the QUAlity and Transparency Of health Research Network guidance for extensions and focused on adding or modifying only essential items.
AHRQ-funded; 290201200004C; 290201200016I; 290201500011I.
Citation: Guise JM, Butler ME, Chang C .
AHRQ series on complex intervention systematic reviews-paper 6: PRISMA-CI extension statement and checklist.
J Clin Epidemiol 2017 Oct;90:43-50. doi: 10.1016/j.jclinepi.2017.06.016.
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Keywords: Evidence-Based Practice, Guidelines, Patient-Centered Outcomes Research, Research Methodologies
Guise JM, Butler M, Chang C
AHRQ Author: Chang C
AHRQ series on complex intervention systematic reviews-paper 7: PRISMA-CI elaboration and explanation.
The Complex Interventions Methods Workgroup developed an extension to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Complex Interventions (PRISMA-CI). Following the guidance for Preferred Reporting Items for Systematic Reviews and Meta-Analysis extensions, this Explanation and Elaboration (EE) document accompanies the PRISMA-CI checklist to promote consistency in reporting of systematic reviews of complex interventions.
AHRQ-authored; AHRQ-funded; 290201200004C; 290201200016I; 290201500011I.
Citation: Guise JM, Butler M, Chang C .
AHRQ series on complex intervention systematic reviews-paper 7: PRISMA-CI elaboration and explanation.
J Clin Epidemiol 2017 Oct;90:51-58. doi: 10.1016/j.jclinepi.2017.06.017.
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Keywords: Data, Evidence-Based Practice, Guidelines, Research Methodologies
Elysee G, Herrin J, Horwitz LI
An observational study of the relationship between meaningful use-based electronic health information exchange, interoperability, and medication reconciliation capabilities.
Stagnation in hospitals' adoption of data integration functionalities coupled with reduction in the number of operational health information exchanges could become a significant impediment to hospitals' adoption of 3 critical capabilities: electronic health information exchange, interoperability, and medication reconciliation, in which electronic systems are used to assist with resolving medication discrepancies and improving patient safety. This observational study examines the relationship between meaningful use-based electronic health information exchange, interoperability, and medication reconciliation capabilities.
AHRQ-funded; HS022882.
Citation: Elysee G, Herrin J, Horwitz LI .
An observational study of the relationship between meaningful use-based electronic health information exchange, interoperability, and medication reconciliation capabilities.
Medicine 2017 Oct;96(41):e8274. doi: 10.1097/MD.0000000000008274..
Keywords: Electronic Health Records (EHRs), Health Information Exchange (HIE), Health Information Technology (HIT), Hospitals, Medication
Yabroff KR, Kirby J, Zodet M
AHRQ Author: Kirby J, Zodet M
Association of insurance gains and losses with access to prescription drugs.
The researchers used longitudinal data to assess the effects of insurance gains and losses on prescription drug access. Their findings that unmet need for prescription drugs declined among initially uninsured adults who gained coverage and doubled among initially insured adults who lost coverage provide longitudinal evidence that having and maintaining health insurance is a key protection against unmet need for prescription drugs in a nationally representative sample.
AHRQ-authored.
Citation: Yabroff KR, Kirby J, Zodet M .
Association of insurance gains and losses with access to prescription drugs.
JAMA Intern Med 2017 Oct;177(10):1531-32. doi: 10.1001/jamainternmed.2017.4011.
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Keywords: Access to Care, Health Insurance, Medication, Medical Expenditure Panel Survey (MEPS), Uninsured
Ndumele CD, Cohen MS, Cleary PD
Association of state access standards with accessibility to specialists for Medicaid managed care enrollees.
The researchers compared ratings of access to specialists for adult Medicaid and commercial enrollees before and after the implementation of specialty access standards. Overall, there was no significant improvement in timely access to specialty services for Medicaid managed care enrollees in the period following implementation of standard(s) nor was there any impact of access standards on insurance-based disparities in access.
AHRQ-funded; HS016978; HS017589.
Citation: Ndumele CD, Cohen MS, Cleary PD .
Association of state access standards with accessibility to specialists for Medicaid managed care enrollees.
JAMA Intern Med 2017 Oct;177(10):1445-51. doi: 10.1001/jamainternmed.2017.3766.
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Keywords: Access to Care, Consumer Assessment of Healthcare Providers and Systems (CAHPS), Quality of Care, Health Insurance, Patient Experience
Boyce RD, Jao J, Miller T
Automated screening of emergency department notes for drug-associated bleeding adverse events occurring in older adults.
The purpose of this study was to conduct research to show the value of text mining for automatically identifying suspected bleeding adverse drug events (ADEs) in the emergency department (ED). The investigators found that both models they examined, accurately identify bleeding ADEs using the presence or absence of certain clinical concepts in ED admission notes for older adult patients.
AHRQ-funded; HS024208.
Citation: Boyce RD, Jao J, Miller T .
Automated screening of emergency department notes for drug-associated bleeding adverse events occurring in older adults.
Appl Clin Inform 2017 Oct;8(4):1022-30. doi: 10.4338/aci-2017-02-ra-0036..
Keywords: Adverse Drug Events (ADE), Elderly, Emergency Department, Medication, Medication: Safety
Mogul DB, Nagy PG, Bridges JFP
Building stronger online communities through the creation of Facebook-integrated health applications.
Social media, such as Facebook, provides a powerful mechanism to connect individuals with similar diseases, but current platforms do not achieve their full potential to help patients communicate with one another or with the medical community. The authors of this viewpoint article believe that an opportunity exists for health care professionals to strengthen online communities by creating apps that use the Facebook platform or a programming interface. Development of such apps are discussed, with an eye toward the needs of the patient, parent, or caregiver as end-users and involving their input.
AHRQ-funded; HS023876.
Citation: Mogul DB, Nagy PG, Bridges JFP .
Building stronger online communities through the creation of Facebook-integrated health applications.
JAMA Pediatr 2017 Oct;171(10):933-34. doi: 10.1001/jamapediatrics.2017.2300..
Keywords: Clinician-Patient Communication, Communication, Education: Patient and Caregiver, Health Information Technology (HIT), Social Media, Web-Based
Masnick M, Morgan DJ, Sorkin JD
Can national healthcare-associated infections (HAIs) data differentiate hospitals in the United States?
This study was designed to determine whether patients using the Centers for Medicare and Medicaid Services (CMS) Hospital Compare website can use nationally reported healthcare-associated infection (HAI) data to differentiate hospitals. The authors concluded that HAI data generally are reported by enough hospitals to meet minimal criteria for useful comparisons in many geographic locations, though this varies by type of HAI.
AHRQ-funded; HS018111.
Citation: Masnick M, Morgan DJ, Sorkin JD .
Can national healthcare-associated infections (HAIs) data differentiate hospitals in the United States?
Infect Control Hosp Epidemiol 2017 Oct;38(10):1167-71. doi: 10.1017/ice.2017.179..
Keywords: Quality of Care, Healthcare-Associated Infections (HAIs), Hospitals, Provider Performance, Quality Measures
Chung S, Panattoni L, Chi J
Can secure patient-provider messaging improve diabetes care?
The authors examined whether messaging with physicians for medical advice is associated with fewer face-to-face visits and better diabetes management. Patients with diabetes using an online portal were studied; 72% used messaging, and those who made frequent visits were also more likely to message. No messaging at all was negatively associated with the likelihood of meeting an HbA1c target. Among message users, additional messages were associated with better outcome, with a stronger relationship for noninsulin users. Physician-initiated messages had effects similar to those for patient-initiated messages.
AHRQ-funded; HS019815.
Citation: Chung S, Panattoni L, Chi J .
Can secure patient-provider messaging improve diabetes care?
Diabetes Care 2017 Oct;40(10):1342-48. doi: 10.2337/dc17-0140.
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Keywords: Communication, Diabetes, Clinician-Patient Communication, Electronic Health Records (EHRs)
Zachrison KS, Hayden EM, Schwamm LH
Characterizing New England emergency departments by telemedicine use.
The primary objective of this study was to describe the prevalence of telemedicine use in New England EDs and the clinical applications of use. It concluded that telemedicine is commonly used in New England EDs. In 2014, use was more common among rural EDs and EDs with limited neurology consultant availability. In contrast, telemedicine use was less common among very low-volume EDs.
AHRQ-funded; HS024561.
Citation: Zachrison KS, Hayden EM, Schwamm LH .
Characterizing New England emergency departments by telemedicine use.
West J Emerg Med 2017 Oct;18(6):1055-60. doi: 10.5811/westjem.2017.8.34880.
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Keywords: Emergency Department, Emergency Medical Services (EMS), Healthcare Delivery, Health Services Research (HSR), Telehealth
Clarity C, Sarkar U, Lee J
Clinician perspectives on the management of abnormal subcritical tests in an urban academic safety-net health care system.
Missed or delayed follow-up of abnormal subcritical tests (tests that do not require immediate medical attention) can lead to poor patient outcomes. Safety-net health systems with limited resources and socially complex patients are vulnerable to safety gaps resulting from delayed management. In this study, clinician perspectives to identify system challenges, vulnerable situations, and potential solutions, were sought in focus groups.
AHRQ-funded; HS023558.
Citation: Clarity C, Sarkar U, Lee J .
Clinician perspectives on the management of abnormal subcritical tests in an urban academic safety-net health care system.
Jt Comm J Qual Patient Saf 2017 Oct;43(10):517-23. doi: 10.1016/j.jcjq.2017.05.007..
Keywords: Urban Health, Rural/Inner-City Residents, Diagnostic Safety and Quality, Patient Safety, Vulnerable Populations, Ambulatory Care and Surgery, Communication, Provider: Clinician
Roghmann MC, Andronescu LR, Stucke EM
Clostridium difficile colonization of nursing home residents.
This letter to the editor notes that Clostridum difficile is a leading cause of infectious diarrhea in nursing homes and asserts that evidence-based infection control guidelines are needed to reduce transmission of C. difficile in these settings.
AHRQ-funded; HS019979.
Citation: Roghmann MC, Andronescu LR, Stucke EM .
Clostridium difficile colonization of nursing home residents.
Infect Control Hosp Epidemiol 2017 Oct;38(10):1267-68. doi: 10.1017/ice.2017.172..
Keywords: Clostridium difficile Infections, Evidence-Based Practice, Guidelines, Nursing Homes
Xavier Moore J, Donnelly JP, Griffin R
Community characteristics and regional variations in sepsis.
This study aimed to determine the influence of community characteristics upon regional variations in sepsis incidence and case fatality. The study concluded that regional variations in sepsis incidence may be partly explained by community poverty. Other community characteristics do not explain regional variations in sepsis incidence or case fatality.
AHRQ-funded; HS013852.
Citation: Xavier Moore J, Donnelly JP, Griffin R .
Community characteristics and regional variations in sepsis.
Int J Epidemiol 2017 Oct 1;46(5):1607-17. doi: 10.1093/ije/dyx099..
Keywords: Disparities, Low-Income, Mortality, Sepsis, Social Determinants of Health
Kangovi S, Mitra N, Grande D
Community health worker support for disadvantaged patients with multiple chronic diseases: a randomized clinical trial.
The researchers sought to determine whether a community health worker (CHW) intervention improved outcomes in a low-income population with multiple chronic conditions. They concluded that a standardized CHW intervention improved chronic disease control, mental health, quality of care, and hospitalizations and could be a useful population health management tool for health care systems.
AHRQ-funded; HS021706.
Citation: Kangovi S, Mitra N, Grande D .
Community health worker support for disadvantaged patients with multiple chronic diseases: a randomized clinical trial.
Am J Public Health 2017 Oct;107(10):1660-67. doi: 10.2105/ajph.2017.303985.
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Keywords: Chronic Conditions, Community-Based Practice, Low-Income, Patient-Centered Outcomes Research
Rudin RS, Fanta CH, Predmore Z
Core components for a clinically integrated mhealth app for asthma symptom monitoring.
The aim of the study was to apply user-centered design principles to efficiently identify core components for a mHealth-based asthma symptom-monitoring intervention using patient-reported outcomes (PROs).
AHRQ-funded; HS023960.
Citation: Rudin RS, Fanta CH, Predmore Z .
Core components for a clinically integrated mhealth app for asthma symptom monitoring.
Appl Clin Inform 2017 Oct;8(4):1031-43. doi: 10.4338/aci-2017-06-ra-0096.
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Keywords: Asthma, Chronic Conditions, Health Information Technology (HIT), System Design
Davies S, Schultz E, Raven M
AHRQ Author: Stocks C
Development and validation of the Agency for Healthcare Research and Quality Measures of Potentially Preventable Emergency Department (ED) Visits: the ED Prevention Quality Indicators for general health conditions.
The researchers sought to develop and validate rates of potentially preventable emergency department (ED) visits as indicators of community health. ED Prevention Quality Indicators (PQI) rates varied widely across U.S. communities. Indicator rates were significantly associated with county-level poverty, median income, Medicaid insurance, and levels of uninsurance. A few indicators were significantly associated with PCP density, with higher rates in areas with greater density.
AHRQ-authored; AHRQ-funded; 2902012000031.
Citation: Davies S, Schultz E, Raven M .
Development and validation of the Agency for Healthcare Research and Quality Measures of Potentially Preventable Emergency Department (ED) Visits: the ED Prevention Quality Indicators for general health conditions.
Health Serv Res 2017 Oct;52(5):1667-84. doi: 10.1111/1475-6773.12687.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Emergency Department, Quality Indicators (QIs), Patient Safety, Prevention
Letourneau LR, Carmody D, Wroblewski K
Diabetes presentation in infancy: high risk of diabetic ketoacidosis.
In this study, the largest of its kind, diabetic ketoacidosis (DKA) was more frequent than in other early-onset U.S. studies or other cohorts of patients with neonatal diabetes. The authors argue that continuing to educate pediatric providers about the many ways that infants can present with diabetes may help to diagnose cases more efficiently and ultimately decrease the frequency of DKA at diagnosis.
AHRQ-funded; HS023007.
Citation: Letourneau LR, Carmody D, Wroblewski K .
Diabetes presentation in infancy: high risk of diabetic ketoacidosis.
Diabetes Care 2017 Oct;40(10):e147-e48. doi: 10.2337/dc17-1145.
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Keywords: Diabetes, Diagnostic Safety and Quality, Newborns/Infants, Children/Adolescents
Quinn JM, Sparks M, Gephart SM
Discharge criteria for the late preterm infant: a review of the literature.
The purpose of this literature review was to examine differences in late preterm infant (LPI) discharge criteria between the well newborn setting and the NICU by answering the clinical questions, "What are the recommended discharge criteria for the LPI and do they differ if admitted to the well newborn setting versus the NICU?"
AHRQ-funded; HS022908.
Citation: Quinn JM, Sparks M, Gephart SM .
Discharge criteria for the late preterm infant: a review of the literature.
Adv Neonatal Care 2017 Oct;17(5):362-71. doi: 10.1097/anc.0000000000000406..
Keywords: Hospital Discharge, Newborns/Infants, Newborns/Infants
Allen CD, McNeely CA
Do restrictive omnibus immigration laws reduce enrollment in public health insurance by Latino citizen children? A comparative interrupted time series study.
This study uses nationally-representative data from the National Health Interview Survey (2005-2014) and comparative interrupted time series methods to assess whether passage of state omnibus immigration laws reduced access to Medicaid/CHIP for US citizen Latino children. The authors found that law passage did not reduce enrollment for children with noncitizen parents and actually resulted in temporary increases in coverage among Latino children with at least one citizen parent.
AHRQ-funded; HS024248.
Citation: Allen CD, McNeely CA .
Do restrictive omnibus immigration laws reduce enrollment in public health insurance by Latino citizen children? A comparative interrupted time series study.
Soc Sci Med 2017 Oct;191:19-29. doi: 10.1016/j.socscimed.2017.08.039..
Keywords: Access to Care, Children/Adolescents, Children's Health Insurance Program (CHIP), Policy, Racial and Ethnic Minorities
Banaszak-Holl J, Reichert H, Todd Greene M
Do safety culture scores in nursing homes depend on job role and ownership? Results from a national survey.
Researchers sought to identify facility- and individual-level predictors of nursing home safety culture. Their survey of nursing home staff (N = 14,177) from 170 of 210 participating facilities found that perceptions of safety culture vary widely among nursing home staff, with administrators consistently perceiving better safety culture than clinical staff who spend more time with residents.
AHRQ-funded; 2902010000251.
Citation: Banaszak-Holl J, Reichert H, Todd Greene M .
Do safety culture scores in nursing homes depend on job role and ownership? Results from a national survey.
J Am Geriatr Soc 2017 Oct;65(10):2244-50. doi: 10.1111/jgs.15030.
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Keywords: Patient Safety, Nursing Homes, Long-Term Care
Burgette JM, Preisser JS, Weinberger M
Early head start, pediatric dental use, and oral health-related quality of life.
The objective of the study was to examine the mediating effect of child dental use on the effectiveness of North Carolina Early Head Start (EHS) in improving oral health-related quality of life (OHRQoL). It concluded that EHS increases child dental use, which worsens family OHRQoL. However, EHS is associated with improved OHRQoL overall.
AHRQ-funded; HS000032.
Citation: Burgette JM, Preisser JS, Weinberger M .
Early head start, pediatric dental use, and oral health-related quality of life.
JDR Clin Trans Res 2017 Oct;2(4):353-62. doi: 10.1177/2380084417709758.
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Keywords: Children/Adolescents, Dental and Oral Health, Quality of Life, Children/Adolescents
Platinga LC, King L, Patzer RE
Early hospital readmission among hemodialysis patients in the United States is associated with subsequent mortality.
The researchers examined the timing of readmissions of hemodialysis patients in the United States and its association with mortality among 285,795 prevalent adult Medicare-primary hemodialysis patients from a national registry. They concluded that regardless of timing, patients with readmissions had a higher risk of death within one year, compared to those with no readmissions.
AHRQ-funded; HS025018.
Citation: Platinga LC, King L, Patzer RE .
Early hospital readmission among hemodialysis patients in the United States is associated with subsequent mortality.
Kidney Int 2017 Oct;92(4):934-41. doi: 10.1016/j.kint.2017.03.025.
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Keywords: Kidney Disease and Health, Hospital Readmissions, Mortality
Burgette JM, Preisser JS, Weinberger M
Enrollment in early head start and oral health-related quality of life.
Researchers examined the effect of enrollment in North Carolina Early Head Start (EHS) - a federally funded early education program for children under three years of age and their families - on oral health-related quality of life (OHRQoL). Their study is the first to demonstrate that families of young children enrolled in EHS report improved OHRQoL compared to their non-enrolled peers.
AHRQ-funded; HS000032.
Citation: Burgette JM, Preisser JS, Weinberger M .
Enrollment in early head start and oral health-related quality of life.
Qual Life Res 2017 Oct;26(10):2607-18. doi: 10.1007/s11136-017-1584-7.
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Keywords: Children/Adolescents, Dental and Oral Health, Quality of Life