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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedShaffer JA, Kronish IM, Falzon L
N-of-1 randomized intervention trials in health psychology: a systematic review and methodology critique.
The purpose of this study was to assess the quality of the methods and statistics, to describe interventions and outcomes, and to explore the heterogeneity of treatment effect of health psychology N-of-1, or single-case randomized clinical trials. Researchers conducted a systematic review of N-of-1 trials by searching numerous databases from their respective inception up to June 2015; studies were included if they had health behavior or psychological outcomes and the order of interventions was randomized. Study characteristics and analytic methods were then abstracted. The results of the study indicate that N-of-1 randomized trials could become the next major advance in health psychology for precision therapeutics, but they must be conducted with more methodologic and statistical rigor as well as be transparently and fully reported.
AHRQ-funded; HS024262.
Citation: Shaffer JA, Kronish IM, Falzon L .
N-of-1 randomized intervention trials in health psychology: a systematic review and methodology critique.
Ann Behav Med 2018 Aug 16;52(9):731-42. doi: 10.1093/abm/kax026..
Keywords: Behavioral Health, Health Services Research (HSR), Research Methodologies