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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 8 of 8 Research Studies DisplayedSobotka SA, Peters S, Pinto NP
Neurodevelopmental disorders in the PICU population.
Attention deficit hyperactivity disorder (ADHD), affecting 11% of children and adolescents, increases risk for injury and may predispose children to illness. However, the prevalence of ADHD and other developmental disorders in the pediatric intensive care unit (PICU) has not been previously studied. In this study, the investigators performed a single-center, prospective cohort study of children aged 6 to 12 years who were hospitalized in the PICU from May through August 2016.
AHRQ-funded; HS023007.
Citation: Sobotka SA, Peters S, Pinto NP .
Neurodevelopmental disorders in the PICU population.
Clin Pediatr 2018 Jul;57(8):913-19. doi: 10.1177/0009922817737080..
Keywords: Children/Adolescents, Intensive Care Unit (ICU), Critical Care, Behavioral Health
Gradidge EA, Bakar A, Tellez D
Safety of tracheal intubation in the presence of cardiac disease in paediatric ICUs.
In this retrospective analysis the investigators sought to evaluate the occurrence of adverse tracheal-intubation-associated events in children with cardiac disease compared to children with non-cardiac disease. The authors found that the overall incidence of adverse tracheal-intubation-associated events in cardiac patients was not different from that in non-cardiac patients. However, the presence of a cardiac diagnosis was associated with a higher occurrence of both tracheal-intubation-associated cardiac arrest and oxygen desaturation.
AHRQ-funded; HS024511.
Citation: Gradidge EA, Bakar A, Tellez D .
Safety of tracheal intubation in the presence of cardiac disease in paediatric ICUs.
Cardiol Young 2018 Jul;28(7):928-37. doi: 10.1017/s1047951118000495..
Keywords: Adverse Events, Cardiovascular Conditions, Children/Adolescents, Intensive Care Unit (ICU), Patient Safety
Gabrani A, Kojima T, Sanders RC, Jr.
Downward trend in pediatric resident laryngoscopy participation in PICUs.
The investigators hypothesized that laryngoscopy by pediatric residents has decreased over time, with a more pronounced decrease after the July 2013 guideline change concerning proficiency in non-neonatal tracheal intubation. They found that laryngoscopy by pediatric residents has substantially decreased over time and this downward trend was not associated with the 2013 Accreditation Council for Graduate Medical Education change in residency requirements.
AHRQ-funded; HS021583; HS022464; HS024511.
Citation: Gabrani A, Kojima T, Sanders RC, Jr. .
Downward trend in pediatric resident laryngoscopy participation in PICUs.
Pediatr Crit Care Med 2018 May;19(5):e242-e50. doi: 10.1097/pcc.0000000000001470.
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Keywords: Children/Adolescents, Intensive Care Unit (ICU), Children/Adolescents
Colwell BRL, Williams CN, Kelly SP
Mobilization therapy in the pediatric intensive care unit: a multidisciplinary quality improvement initiative.
The authors sought to implement a standardized mobilization therapy protocol in a pediatric intensive care unit and improve mobilization of patients. They found that a multidisciplinary, multiprofessional, goal-directed mobilization protocol achieved goal mobilization in more than 50% of patients in the studied pediatric intensive care unit, with undermobilized patients being older, less ill, and more likely to have mobilization barriers at the patient and provider level.
AHRQ-funded; HS022981.
Citation: Colwell BRL, Williams CN, Kelly SP .
Mobilization therapy in the pediatric intensive care unit: a multidisciplinary quality improvement initiative.
Am J Crit Care 2018 May;27(3):194-203. doi: 10.4037/ajcc2018193.
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Keywords: Children/Adolescents, Intensive Care Unit (ICU), Patient-Centered Healthcare, Children/Adolescents, Quality Improvement
Gradidge EA, Bakar A, Tellez D
Effect of location on tracheal intubation safety in cardiac disease-are cardiac ICUs safer?
In this retrospective cohort study, the investigators evaluate differences in tracheal intubation-associated events and process variances (i.e., multiple intubation attempts and oxygen desaturation) between pediatric cardiac ICUs and noncardiac PICUs in children with underlying cardiac disease. The authors found that in children with underlying cardiac disease, rates of adverse tracheal intubation-associated events were not lower in cardiac ICUs as compared to noncardiac ICUs, even after adjusting for differences in patient characteristics and care models.
AHRQ-funded; HS024511.
Citation: Gradidge EA, Bakar A, Tellez D .
Effect of location on tracheal intubation safety in cardiac disease-are cardiac ICUs safer?
Pediatr Crit Care Med 2018 Mar;19(3):218-27. doi: 10.1097/pcc.0000000000001422..
Keywords: Adverse Events, Cardiovascular Conditions, Children/Adolescents, Intensive Care Unit (ICU), Patient Safety
Kojima T, Laverriere EK, Owen EB
Clinical impact of external laryngeal manipulation during laryngoscopy on tracheal intubation success in critically ill children.
In this retrospective observational study, the objective was to evaluate the association between external laryngeal manipulation use and initial tracheal intubation attempt success in pediatric ICUs. The investigators found that external laryngeal manipulation during direct laryngoscopy was associated with lower initial tracheal intubation attempt success in critically ill children, even after adjusting for underlying differences in patient factors and provider levels. They asserted that the indiscriminate use of external laryngeal manipulation cannot be recommended.
AHRQ-funded; HS024511.
Citation: Kojima T, Laverriere EK, Owen EB .
Clinical impact of external laryngeal manipulation during laryngoscopy on tracheal intubation success in critically ill children.
Pediatr Crit Care Med 2018 Feb;19(2):106-14. doi: 10.1097/pcc.0000000000001373..
Keywords: Children/Adolescents, Critical Care, Intensive Care Unit (ICU), Children/Adolescents, Respiratory Conditions
Langhan ML, Emerson BL, Nett S
End-tidal carbon dioxide use for tracheal intubation: analysis from the National Emergency Airway Registry for Children (NEAR4KIDS) Registry.
The purpose of this study was to describe the trend in waveform capnography use in emergency departments and pediatric intensive care units and assess the association between waveform capnography use and adverse tracheal intubation-associated events. The investigators found that significant variations existed in capnography use across institutions, with the use increasing over time in both emergency departments and ICUs. The use of capnography during intubation was not associated with esophageal intubation with delayed recognition or the occurrence of cardiac arrest.
AHRQ-funded; HS024511.
Citation: Langhan ML, Emerson BL, Nett S .
End-tidal carbon dioxide use for tracheal intubation: analysis from the National Emergency Airway Registry for Children (NEAR4KIDS) Registry.
Pediatr Crit Care Med 2018 Feb;19(2):98-105. doi: 10.1097/pcc.0000000000001372..
Keywords: Children/Adolescents, Emergency Department, Intensive Care Unit (ICU), Children/Adolescents
Nett S, Emeriaud G, Jarvis JD
Site-level variance for adverse tracheal intubation-associated events across 15 North American PICUs: a report from the national emergency airway registry for children*.
This observational study of 15 pediatric intensive care units (PICUs) found that substantial site-level variance exists in tracheal intubation practice, adverse tracheal intubation associated-events and severe tracheal intubation associated-events. After adjusting for patient and provider characteristics, neither PICU size nor presence of fellowship training program explained site-level variance.
AHRQ-funded; HS021583
Citation: Nett S, Emeriaud G, Jarvis JD .
Site-level variance for adverse tracheal intubation-associated events across 15 North American PICUs: a report from the national emergency airway registry for children*.
Pediatr Crit Care Med. 2014 May;15(4):306-13. doi: 10.1097/pcc.0000000000000120..
Keywords: Children/Adolescents, Intensive Care Unit (ICU), Registries, Adverse Events