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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedSaffo S, Kaplan DE, Mahmud N
Impact of SGLT2 inhibitors in comparison with DPP4 inhibitors on ascites and death in veterans with cirrhosis on metformin.
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) may have favourable neurohumoral and metabolic effects in patients with chronic liver disease. However, studies examining SGLT2i in this population have been limited to patients with non-alcoholic fatty liver disease and have focused on surrogate biomarkers. The aim of this study was to evaluate whether SGLT2i could reduce the incidence of ascites and death over a period of 36 months in patients with cirrhosis and diabetes mellitus.
AHRQ-funded; HS022882; HS025164.
Citation: Saffo S, Kaplan DE, Mahmud N .
Impact of SGLT2 inhibitors in comparison with DPP4 inhibitors on ascites and death in veterans with cirrhosis on metformin.
Diabetes Obes Metab 2021 Oct;23(10):2402-08. doi: 10.1111/dom.14488..
Keywords: Diabetes