National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1801 to 1825 of 1870 Research Studies DisplayedNundy S, Dick JJ, Chou CH
Mobile phone diabetes project led to improved glycemic control and net savings for Chicago plan participants.
Mobile phones are a promising tool to use in engaging patients in behavior change and facilitating self-care between visits. The researchers examined the impact of a six-month mobile health (mHealth) demonstration project among adults with diabetes. In addition to pre-post improvements in glycemic control and patients’ satisfaction with overall care, they observed a net cost savings of 8.8 percent.
AHRQ-funded; HS000084.
Citation: Nundy S, Dick JJ, Chou CH .
Mobile phone diabetes project led to improved glycemic control and net savings for Chicago plan participants.
Health Aff 2014 Feb;33(2):265-72. doi: 10.1377/hlthaff.2013.0589..
Keywords: Diabetes, Health Information Technology (HIT), Patient Adherence/Compliance, Patient Self-Management, Telehealth
Mitchell SE, Gardiner PM, Sadikova E
Patient activation and 30-day post-discharge hospital utilization.
This study examining the role of patient activation in the rate of hospital readmission within 30 days of discharge found that adult medical patients in an urban academic safety net hospital with lower levels of patient activation had a higher rate of post-discharge 30-day hospital utilization.
AHRQ-funded; HS019771.
Citation: Mitchell SE, Gardiner PM, Sadikova E .
Patient activation and 30-day post-discharge hospital utilization.
J Gen Intern Med. 2014 Feb;29(2):349-55. doi: 10.1007/s11606-013-2647-2..
Keywords: Emergency Department, Hospital Discharge, Hospital Readmissions, Hospitalization
Brach C, Dreyer BP, Schillinger D
AHRQ Author: Brach C
Physicians' roles in creating health literate organizations: a call to action.
Physicians are being called on to deliver patient-centered care, reduce medical errors, and generally increase health care quality and health outcomes, all while containing costs. Fully engaging patients in prevention, decision-making and self-management activities is critical to achieving these aims. The authors of this paper concluded that being health literate must be a new way of delivering care rather than an add-on. For national health literacy goals to be met, health care organizations must ingrain health literacy into their routines.
AHRQ-authored.
Citation: Brach C, Dreyer BP, Schillinger D .
Physicians' roles in creating health literate organizations: a call to action.
J Gen Intern Med 2014 Feb;29(2):273-5. doi: 10.1007/s11606-013-2619-6.
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Keywords: Healthcare Delivery, Decision Making, Health Literacy, Patient and Family Engagement, Patient-Centered Healthcare
Hwang TJ, Avorn J, Carpenter D
Quantifying the Food And Drug Administration's rulemaking delays highlights the need for transparency.
In order to better understand the FDA’s rulemaking process, the authors examined the evolution of significant rules that the agency published during 2000–12 for drugs, devices, and other medical products. They found that the rules’ median time to finalization was 7.3 years. Longer review times were significantly associated with a reduction in the stringency of final rules, compared to the originally proposed versions.
AHRQ-funded; HS018465.
Citation: Hwang TJ, Avorn J, Carpenter D .
Quantifying the Food And Drug Administration's rulemaking delays highlights the need for transparency.
Health Aff 2014 Feb;33(2):309-15. doi: 10.1377/hlthaff.2013.0564..
Keywords: Patient Safety, Policy, Decision Making, Medication
Ezaz G, Long JB, Gross CP
Risk prediction model for heart failure and cardiomyopathy after adjuvant trastuzumab therapy for breast cancer.
The investigators sought to develop a clinical risk score that identifies older women with breast cancer who are at higher risk of heart failure or cardiomyopathy after trastuzumab. That found that a 7-factor risk score was able to stratify 3-year risk of heart failure/cardiomyopathy after trastuzumab between the lowest and highest risk groups by more than 2-fold in a Medicare population.
AHRQ-funded; HS018781.
Citation: Ezaz G, Long JB, Gross CP .
Risk prediction model for heart failure and cardiomyopathy after adjuvant trastuzumab therapy for breast cancer.
J Am Heart Assoc 2014 Feb;3(1):e000472. doi: 10.1161/jaha.113.000472.
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Keywords: Cancer: Breast Cancer, Heart Disease and Health, Medication, Patient Safety, Risk
Earley A, Persson R, Garlitski AC
Effectiveness of implantable cardioverter defibrillators for primary prevention of sudden cardiac death in subgroups a systematic review.
The purpose of this review was to examine ICD effectiveness for primary prevention of SCD across subgroups by sex, age, QRS interval, time since myocardial infarction, blood urea nitrogen level, and diabetes. It concluded that there was weak evidence showing differences for all-cause mortality in subgroups of sex, age, and QRS interval. Also, evidence was indeterminate for all-cause mortality in the other subgroups and for SCD.
AHRQ-funded; 290200710055I.
Citation: Earley A, Persson R, Garlitski AC .
Effectiveness of implantable cardioverter defibrillators for primary prevention of sudden cardiac death in subgroups a systematic review.
Ann Intern Med 2014 Jan 21;160(2):111-21. doi: 10.7326/m13-1787..
Keywords: Medical Devices, Comparative Effectiveness, Prevention, Mortality
Blecker S, Agarwal SK, Chang PP
Quality of care for heart failure patients hospitalized for any cause.
This study sought to assess the quality of care for heart failure patients who are hospitalized for all causes. The investigators found that compared with individuals hospitalized with a principal diagnosis of heart failure, heart failure patients hospitalized for other causes were less likely to receive guideline recommended care.
AHRQ-funded; HS023683.
Citation: Blecker S, Agarwal SK, Chang PP .
Quality of care for heart failure patients hospitalized for any cause.
J Am Coll Cardiol 2014 Jan 21;63(2):123-30. doi: 10.1016/j.jacc.2013.08.1628..
Keywords: Cardiovascular Conditions, Heart Disease and Health, Hospitalization, Quality of Care
Pershing S, Enns EA, Matesic B
Cost-effectiveness of treatment of diabetic macular edema.
The researchers sought to determine the cost-effectiveness of different treatments of diabetic macular edema (DME). They found that vascular endothelial growth factor (VEGF) inhibitors with or without laser treatment provide important health benefits with favorable cost-effectiveness, costing less per QALY gained than many accepted therapies.
AHRQ-funded; HS000028.
Citation: Pershing S, Enns EA, Matesic B .
Cost-effectiveness of treatment of diabetic macular edema.
Ann Intern Med 2014 Jan 7;160(1):18-29. doi: 10.7326/m13-0768..
Keywords: Diabetes, Eye Disease and Health, Healthcare Costs, Quality of Life, Treatments
Nuckols TK, Anderson L, Popescu I
Opioid prescribing: a systematic review and critical appraisal of guidelines for chronic pain.
This review evaluated the quality and content of guidelines on the use of opioids for chronic pain. Despite limited evidence and variable development methods, it concluded that recent guidelines on chronic pain agree on several opioid risk mitigation strategies, including upper dosing thresholds; cautions with certain medications; attention to drug–drug and drug–disease interactions; and use of risk assessment tools, treatment agreements, and urine drug testing.
AHRQ-funded; HS017954.
Citation: Nuckols TK, Anderson L, Popescu I .
Opioid prescribing: a systematic review and critical appraisal of guidelines for chronic pain.
Ann Intern Med 2014 Jan 7;160(1):38-47. doi: 10.7326/0003-4819-160-1-201401070-00732..
Keywords: Opioids, Pain, Guidelines, Medication, Evidence-Based Practice, Chronic Conditions
Kronick R, McKinney M
AHRQ Author: Kronick R
Ready to provide evidence for ‘making adjustments’ in Obamacare.
In this interview with Modern Healthcare, Richard Kronick, director of the Agency for Healthcare Research and Quality (AHRQ), states that his main objective for AHRQ is to produce evidence to improve the quality, safety, accessibility, and affordability of health care. He discusses several AHRQ programs and places them in the context of changes in the healthcare system triggered by Affordable Care Act.
AHRQ-authored
Citation: Kronick R, McKinney M .
Ready to provide evidence for ‘making adjustments’ in Obamacare.
Mod Healthc. 2014 Jan 6;44(1):28-9..
Keywords: Healthcare Costs, Quality of Care, Policy, Patient Safety
Enayati M, Banerjee T, Popescu M
A novel web-based depth video rewind approach toward fall preventive interventions in hospitals.
The purpose of this study was to implement a web-based application to provide the ability to rewind and review depth videos captured in hospital rooms to investigate the event chains that led to patient’s fall at a specific time. It proposes a novel web application to ease the process of search and review of the videos by means of new visualization techniques to highlight video frames that contain potential risk of fall based on our previous research.
AHRQ-funded; HS018477.
Citation: Enayati M, Banerjee T, Popescu M .
A novel web-based depth video rewind approach toward fall preventive interventions in hospitals.
Conf Proc IEEE Eng Med Biol Soc 2014;2014:4511-4. doi: 10.1109/embc.2014.6944626..
Keywords: Health Information Technology (HIT), Web-Based, Falls, Hospitals
Newman-Toker DE
A unified conceptual model for diagnostic errors: underdiagnosis, overdiagnosis, and misdiagnosis.
Newman-Toker proposed a novel framework for considering diagnostic errors, offering a unified conceptual model for underdiagnosis, overdiagnosis, and misdiagnosis, concluding that the model should serve as a foundation for developing consensus terminology and operationalized definitions for relevant diagnostic-error categories.
AHRQ-funded; HS019252.
Citation: Newman-Toker DE .
A unified conceptual model for diagnostic errors: underdiagnosis, overdiagnosis, and misdiagnosis.
Diagnosis 2014 Jan;1(1):43-48. doi: 10.1515/dx-2013-0027.
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Keywords: Diagnostic Safety and Quality, Medical Errors, Patient Safety
Barnett ML, Linder JA
Antibiotic prescribing to adults with sore throat in the United States, 1997-2010.
In only about 10 percent of cases of sore throat (those related to A Streptococcus infection) are antibiotics indicated. However, a new study, combined with an earlier study, finds that despite efforts to reduce overprescribing, antibiotic use dropped from roughly 80 to 70 percent around 1993 and then to around 60 percent by 2000 where it has remained as of 2010.
AHRQ-funded; HS018419
Citation: Barnett ML, Linder JA .
Antibiotic prescribing to adults with sore throat in the United States, 1997-2010.
JAMA Intern Med. 2014 Jan;174(1):138-40. doi: 10.1001/jamainternmed.2013.11673..
Keywords: Antibiotics, Antimicrobial Stewardship, Medication, Healthcare Utilization
Donnelly JP, Baddley JW, Wang HE
Antibiotic utilization for acute respiratory tract infections in U.S. emergency departments.
Using national surveillance data for acute respiratory tract infections (ARTIs), this study characterized patterns of antibiotic usage in U.S. emergency departments between 2001 and 2010. It found significant progress toward reductions on inappropriate antibiotic use among children; however, adults with ARTI continued to receive inappropriately high amounts of antibiotics.
AHRQ-funded; HS013852
Citation: Donnelly JP, Baddley JW, Wang HE .
Antibiotic utilization for acute respiratory tract infections in U.S. emergency departments.
Antimicrob Agents Chemother. 2014 Mar;58(3):1451-7. doi: 10.1128/AAC.02039-13..
Keywords: Antimicrobial Stewardship, Emergency Medical Services (EMS), Medication, Critical Care
Rome BN, Kramer DB, Kesselheim AS
Approval of high-risk medical devices in the US: implications for clinical cardiology.
The authors review the premarket approval (PMA) process to approve high-risk cardiovascular devices, as well as the five different types of PMA supplements used to approve alterations to device design. They summarize the types of data required to approve new high-risk cardiovascular devices and discuss implications of the PMA process for clinicians and patients.
AHRQ-funded; HS018465
Citation: Rome BN, Kramer DB, Kesselheim AS .
Approval of high-risk medical devices in the US: implications for clinical cardiology.
Curr Cardiol Rep. 2014;16(6):489. doi: 10.1007/s11886-014-0489-0..
Keywords: Medical Devices, Cardiovascular Conditions, Patient Safety
Hendrich A, McCoy CK, Gale J
Ascension health's demonstration of full disclosure protocol for unexpected events during labor and delivery shows promise.
This article presents a case study concerning challenges, including physician resistance, to the establishment of a common full disclosure protocol at five labor and delivery demonstration sites. Twenty-seven months after implementation, the rate of full disclosure had increased by 221 percent. Practitioners saw a number of factors as key catalysts for change including consistent and ongoing leadership by local practitioners and hospitals.
AHRQ-funded; HS019608.
Citation: Hendrich A, McCoy CK, Gale J .
Ascension health's demonstration of full disclosure protocol for unexpected events during labor and delivery shows promise.
Health Aff 2014 Jan;33(1):39-45. doi: 10.1377/hlthaff.2013.1009..
Keywords: Adverse Events, Clinician-Patient Communication, Communication, Labor and Delivery, Medical Errors, Medical Liability, Policy, Pregnancy, Women
Stone EE, Skubic M, Back J
Automated health alerts from Kinect-based in-home gait measurements.
This paper details initial investigation of a method for automatically generating alerts to clinicians in response to changes in in-home gait parameters. The three case studies discussed illustrate the potential of automated alerts based on in-home gait data for notifying caregivers of changes in an individual's gait that may be indicative of changes in health status.
AHRQ-funded; HS018477.
Citation: Stone EE, Skubic M, Back J .
Automated health alerts from Kinect-based in-home gait measurements.
Conf Proc IEEE Eng Med Biol Soc 2014;2014:2961-4. doi: 10.1109/embc.2014.6944244..
Keywords: Patient Safety, Health Information Technology (HIT), Elderly, Falls
Liu KY, Haukoos JS, Sasson C
Availability and quality of cardiopulmonary resuscitation information for Spanish-speaking population on the Internet.
The goal of this study was to evaluate the availability and quality of CPR-related literature for Spanish-speaking-only individuals on the Internet. It found that only 1 in 7 websites on the Internet has quality hands-only CPR education for this population.
AHRQ-funded; HS017526.
Citation: Liu KY, Haukoos JS, Sasson C .
Availability and quality of cardiopulmonary resuscitation information for Spanish-speaking population on the Internet.
Resuscitation. 2014 Jan;85(1):131-7. doi: 10.1016/j.resuscitation.2013.08.274..
Keywords: Education: Patient and Caregiver, Cultural Competence, Disparities, Racial and Ethnic Minorities, Web-Based
Norton BL, Person AK, Castillo C
Barriers to using text message appointment reminders in an HIV clinic.
The researchers conducted a randomized, controlled trial of text message reminders in a large HIV clinic. They found that there were no differences in clinic attendance rates between the group that received text reminders versus the group that did not (72 versus 81 percent). They concluded that barriers must be addressed before they are used as a universal approach to improve clinic attendance.
AHRQ-funded; HS000079.
Citation: Norton BL, Person AK, Castillo C .
Barriers to using text message appointment reminders in an HIV clinic.
Telemed J E Health 2014 Jan;20(1):86-9. doi: 10.1089/tmj.2012.0275..
Keywords: Communication, Health Information Technology (HIT), Human Immunodeficiency Virus (HIV), Patient Adherence/Compliance
Arora VM, Reed DA, Fletcher KE
Building continuity in handovers with shorter residency duty hours.
The authors discuss how “continuity-enhanced handovers” differ from traditional handovers in several key aspects, including quality of information transferred, greater professional responsibility of senders and receivers, and a different philosophy of “coverage.” By reconceptualizing handover as a necessary bridge to continuity, and hence to safer patient care, this model of continuity-enhanced handovers has the potential to allay fears and improve patient care in an era of increasing fragmentation.
AHRQ-funded; HS018278.
Citation: Arora VM, Reed DA, Fletcher KE .
Building continuity in handovers with shorter residency duty hours.
BMC Med Educ 2014;14 Suppl 1:S16. doi: 10.1186/1472-6920-14-s1-s16..
Keywords: Quality of Care, Patient Safety, Care Coordination
Haas MC, Bodner EV, Brown CJ
Calorie restriction in overweight seniors: response of older adults to a dieting study: the CROSSROADS randomized controlled clinical trial.
The researchers conducted a study designed to evaluate whether the benefits of intentional weight loss exceed the potential risks in a group of community-dwelling obese older adults. The development and implementation of the CROSSROADS protocol, including a description of the methodology, as well as unique data management features of the trial results, are presented in this article.
AHRQ-funded; HS013852.
Citation: Haas MC, Bodner EV, Brown CJ .
Calorie restriction in overweight seniors: response of older adults to a dieting study: the CROSSROADS randomized controlled clinical trial.
J Nutr Gerontol Geriatr 2014;33(4):376-400. doi: 10.1080/21551197.2014.965993..
Keywords: Elderly, Nutrition, Obesity
Sockolow PS, Bowles KH, Adelsberger MC
Challenges and facilitators to adoption of a point-of-care electronic health record in home care.
In order to identify challenges to the adoption of electronic health records (EHR) in the home care setting, the researchers assessed clinician satisfaction, informed by workflow and patient outcomes. Using a combination of surveys, observations, and interviews in an agency with 137 clinicians, the researchers found that adoption challenges included: (a) hardware problems coupled with lack of field support; (b) inadequate training; and (c) mismatch of EHR usability/functionality and workflow.
AHRQ-funded; HS021008.
Citation: Sockolow PS, Bowles KH, Adelsberger MC .
Challenges and facilitators to adoption of a point-of-care electronic health record in home care.
Home Health Care Serv Q 2014;33(1):14-35. doi: 10.1080/01621424.2013.870098..
Keywords: Health Information Technology (HIT), Electronic Health Records (EHRs), Home Healthcare
Hartung DM, Zerzan J, Yamashita T
Characteristics and trends of low-dose quetiapine use in two western state Medicaid programs.
This study characterized longitudinal trends in low-dose second-generation antipsychotic medications, and, in particular, quetiapine in two western State Medicaid programs over a 5-year period. The researchers found that when one State suspended off-label promotional activities, there was a significant decline in the initiation of low-dose quetiapine use.
AHRQ-funded; HS019456; HS019464.
Citation: Hartung DM, Zerzan J, Yamashita T .
Characteristics and trends of low-dose quetiapine use in two western state Medicaid programs.
Pharmacoepidemiol Drug Saf. 2014 Jan;23(1):87-94. doi: 10.1002/pds.3538..
Keywords: Medication, Medicaid, Behavioral Health
Lawrence WF
AHRQ Author: Lawrence WF
Comparative effectiveness research in practice and policy for radiation oncology.
In radiation oncology, the line between comparative effectiveness research (CER) and traditional research may be blurred, but an increased emphasis on CER can help to bridge the research enterprise and clinical practice, helping to inform decision making at the patient, clinician, and policy levels.
AHRQ-authored.
Citation: Lawrence WF .
Comparative effectiveness research in practice and policy for radiation oncology.
Semin Radiat Oncol 2014 Jan;24(1):54-60. doi: 10.1016/j.semradonc.2013.09.001.
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Keywords: Comparative Effectiveness, Evidence-Based Practice, Guidelines, Policy, Research Methodologies
Dimick JB, Birkmeyer NJ, Finks JF
Composite measures for profiling hospitals on bariatric surgery performance.
The study objective was to develop a novel composite measure for profiling hospital performance with bariatric surgery. Composite measures are much better at explaining hospital-level variation in serious complications and predicting future performance than other approaches. This study provides preliminary data that empirically weighted composite outcomes measures may be better than existing alternatives for selective referral and outcomes feedback programs.
AHRQ-funded; HS017765.
Citation: Dimick JB, Birkmeyer NJ, Finks JF .
Composite measures for profiling hospitals on bariatric surgery performance.
JAMA Surg 2014 Jan;149(1):10-6. doi: 10.1001/jamasurg.2013.4109..
Keywords: Adverse Events, Quality of Care, Hospitals