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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
Results1 to 3 of 3 Research Studies Displayed
Rosenman MB, Szucs KA, Finnell SM
Nascent regional system for alerting infection preventionists about patients with multidrug-resistant gram-negative bacteria: implementation and initial results.
The authors sought to build and to begin evaluating a regional automated system to notify infection preventionists (IPs) when a patient with a history of gram-negative rod multidrug-resistant organism (GNRMDRO) is admitted to an emergency department (ED) or inpatient setting. They found it feasible to create a regional microbiology-based alert system and observed substantial crossover between institutions. They concluded that this system, if it contributes to timely isolation, may help reduce the spread of GNRMDROs.
Citation: Rosenman MB, Szucs KA, Finnell SM . Nascent regional system for alerting infection preventionists about patients with multidrug-resistant gram-negative bacteria: implementation and initial results. Infect Control Hosp Epidemiol 2014 Oct;35 Suppl 3:S40-7. doi: 10.1086/677833.
Keywords: Emergency Department, Infectious Diseases, Inpatient Care, Patient Safety, Prevention
Jacobs JH, Viboud C, Tchetgen ET
AHRQ Author: Steiner C
The association of meningococcal disease with influenza in the United States, 1989-2009.
The purpose of this paper is to quantify the fraction of meningococcal disease attributable to influenza. The authors found that, over 20 years, 12.8% of meningococcal disease can be attributable to influenza in the preceding weeks with H3N2 accounting for 5.2%, H1N1 4.3%, B 3.0%, and pH1N1 0.2%. They concluded that influenza vaccination could provide protection, particularly in young children where the meningococcal disease vaccine is not recommended or protective against the most common serogroup.
Citation: Jacobs JH, Viboud C, Tchetgen ET . The association of meningococcal disease with influenza in the United States, 1989-2009. PLoS One 2014 Sep 29;9(9):e107486. doi: 10.1371/journal.pone.0107486.
Keywords: Healthcare Cost and Utilization Project (HCUP), Infectious Diseases, Influenza
Kappagoda S, Ioannidis JP
Prevention and control of neglected tropical diseases: overview of randomized trials, systematic reviews and meta-analyses.
The purpose of this review was to analyze evidence from randomized controlled trials (RCTs) on the prevention and control of neglected tropical diseases (NTDs) and to identify areas where evidence is lacking. The most studied diseases were geohelminth infection (51 RCTs) and leishmaniasis (46 RCTs). Vaccines, chemoprophylaxis and interventions targeting insect vectors were evaluated in 113, 99 and 39 RCTs, respectively. Few addressed how best to deliver preventive chemotherapy.
Citation: Kappagoda S, Ioannidis JP . Prevention and control of neglected tropical diseases: overview of randomized trials, systematic reviews and meta-analyses. Bull World Health Organ 2014 May;92(5):356-66c. doi: 10.2471/blt.13.129601..
Keywords: Prevention, Innovations and Emerging Issues, Evidence-Based Practice, Infectious Diseases