National Healthcare Quality and Disparities Report
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Topics
- Access to Care (2)
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- Disparities (1)
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- (-) Human Immunodeficiency Virus (HIV) (22)
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- Racial and Ethnic Minorities (5)
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- Screening (3)
- Sexual Health (1)
- Simulation (1)
- Social Determinants of Health (1)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 22 of 22 Research Studies DisplayedTuran B, Rogers AJ, Rice WS
Association between perceived discrimination in healthcare settings and HIV medication adherence: mediating psychosocial mechanisms.
There is insufficient research on the impact of perceived discrimination in healthcare settings on adherence to antiretroviral therapy (ART), particularly among women living with HIV, and even less is known about psychosocial mechanisms that may mediate this association. Cross-sectional analyses were conducted in a sample of diverse women living with HIV enrolled in the Women's Interagency HIV Study (WIHS), a multi-center cohort study to investigate these issues.
AHRQ-funded; HS013852.
Citation: Turan B, Rogers AJ, Rice WS .
Association between perceived discrimination in healthcare settings and HIV medication adherence: mediating psychosocial mechanisms.
AIDS Behav 2017 Dec;21(12):3431-39. doi: 10.1007/s10461-017-1957-5..
Keywords: Human Immunodeficiency Virus (HIV), Medication, Patient Adherence/Compliance, Social Stigma
Gao TY, Howe CJ, Zullo AR
Risk factors for self-report of not receiving an HIV test among adolescents in NYC with a history of sexual intercourse, 2013 YRBS.
This study estimated the prevalence of and identified risk factors for not receiving an HIV test among adolescents with a history of sexual intercourse in New York City (NYC), an urban area that has been greatly impacted by the HIV epidemic. The study’s findings suggested that among NYC adolescents with a history of sexual intercourse, the prevalence of HIV testing is low. HIV testing may have been low in part because of limited experience with current screening guidelines among clinicians.
AHRQ-funded; HS022998.
Citation: Gao TY, Howe CJ, Zullo AR .
Risk factors for self-report of not receiving an HIV test among adolescents in NYC with a history of sexual intercourse, 2013 YRBS.
Vulnerable Child Youth Stud 2017;12(4):277-91. doi: 10.1080/17450128.2016.1268741..
Keywords: Children/Adolescents, Human Immunodeficiency Virus (HIV), Lifestyle Changes, Screening, Urban Health
Wang D
Use contexts and usage patterns of interactive case simulation tools by HIV healthcare providers in a statewide online clinical education program.
The researcher analyzed four interactive case simulation tools (ICSTs) from a statewide online clinical education program. Results have shown that ICSTs are increasingly used by HIV healthcare providers. Smart phone has become the primary usage platform for specific ICSTs. Usage patterns depend on particular ICST modules, usage stages, and use contexts.
AHRQ-funded; HS022057.
Citation: Wang D .
Use contexts and usage patterns of interactive case simulation tools by HIV healthcare providers in a statewide online clinical education program.
Stud Health Technol Inform 2017;245:1242.
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Keywords: Education: Continuing Medical Education, Health Information Technology (HIT), Human Immunodeficiency Virus (HIV), Provider, Simulation, Training
Lo Re VR, Zeldow B, Kallan MJ
Risk of liver decompensation with cumulative use of mitochondrial toxic nucleoside analogues in HIV/hepatitis C virus coinfection.
This cohort study was conducted to determine if cumulative mitochondrial toxic nucleoside reverse transcriptase inhibitors (mtNRTI) use increased the risk of hepatic decompensation and death among patients coinfected with human immunodeficiency virus (HIV) and chronic hepatitis C virus (HCV). The findings suggest that cumulative mtNRTI use may increase the risk of hepatic decompensation and death in HIV/HCV coinfection and should be avoided when alternatives exist for HIV/HCV patients.
AHRQ-funded; HS018372.
Citation: Lo Re VR, Zeldow B, Kallan MJ .
Risk of liver decompensation with cumulative use of mitochondrial toxic nucleoside analogues in HIV/hepatitis C virus coinfection.
Pharmacoepidemiol Drug Saf 2017 Oct;26(10):1172-81. doi: 10.1002/pds.4258..
Keywords: Adverse Drug Events (ADE), Hepatitis, Human Immunodeficiency Virus (HIV), Medication, Patient Safety
Young LE, Michaels S, Jonas A
Sex behaviors as social cues motivating social venue patronage among young black men who have sex with men.
This study presents a two-mode network analysis that determines the extent that three types of sex behaviors-condomless sex, sex-drug use, and group sex-influence the patronage of different types of social venues among a population sample of young Black men who have sex with men. Its findings demonstrate that social venues can function as intermediary contexts in which relationships can form between individuals that have greater risk potential.
AHRQ-funded; HS000084.
Citation: Young LE, Michaels S, Jonas A .
Sex behaviors as social cues motivating social venue patronage among young black men who have sex with men.
AIDS Behav 2017 Oct;21(10):2924-34. doi: 10.1007/s10461-017-1679-8.
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Keywords: Lifestyle Changes, Human Immunodeficiency Virus (HIV), Racial and Ethnic Minorities, Substance Abuse
Eaton EF, McDavid C, Banasiewicz MK
Patient preferences for antiretroviral therapy: effectiveness, quality of life, access and novel delivery methods.
The objective of this study was to understand patient preferences for contemporary antiretroviral therapy (ART) by focusing on three areas that have been understudied: minority patients (racial/ethnic and sexual minorities), experience with novel single-tablet regimens made available in the last 10 years, and patient concerns related to ART. It concluded that HIV-infected persons prioritize access, clinical outcomes, and quality of life when considering contemporary ART treatment.
AHRQ-funded; HS023009.
Citation: Eaton EF, McDavid C, Banasiewicz MK .
Patient preferences for antiretroviral therapy: effectiveness, quality of life, access and novel delivery methods.
Patient Prefer Adherence 2017 Sep 18;11:1585-90. doi: 10.2147/ppa.s142643.
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Keywords: Access to Care, Human Immunodeficiency Virus (HIV), Racial and Ethnic Minorities, Racial and Ethnic Minorities
Monroe AK, Fleishman JA, Voss CC
AHRQ Author: Fleishman JA
Assessing antiretroviral use during gaps in HIV primary care using multisite Medicaid claims and clinical data.
Some individuals who appear poorly retained by clinic visit-based retention measures are using antiretroviral therapy (ART) and maintaining viral suppression. Researchers examined whether individuals with a gap in HIV primary care (>/=180 days between HIV outpatient clinic visits) obtained ART during that gap after 180 days. They found that Medicaid-insured individuals commonly receive ART during gaps in HIV primary care, but almost half do not.
AHRQ-authored; AHRQ-funded; 290201100007C.
Citation: Monroe AK, Fleishman JA, Voss CC .
Assessing antiretroviral use during gaps in HIV primary care using multisite Medicaid claims and clinical data.
J Acquir Immune Defic Syndr 2017 Sep 1;76(1):82-89. doi: 10.1097/qai.0000000000001469.
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Keywords: Access to Care, Human Immunodeficiency Virus (HIV), Primary Care
Rowell-Cunsolo TL, Cortes YI, Long Y
Acceptability of rapid HIV testing among Latinos in Washington Heights, New York City, New York, USA.
In the United States, human immunodeficiency virus (HIV) has a disproportionately large impact on Latino Americans. Seventy-five percent of those surveyed accepted rapid HIV testing when offered. More religious participants were less likely than less religious participants to undergo testing. Participants tested for HIV within the past year were less likely than those who had not been tested within the past year to agree to undergo testing.
AHRQ-funded; HS022961.
Citation: Rowell-Cunsolo TL, Cortes YI, Long Y .
Acceptability of rapid HIV testing among Latinos in Washington Heights, New York City, New York, USA.
J Immigr Minor Health 2017 Aug;19(4):861-67. doi: 10.1007/s10903-016-0525-9.
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Keywords: Health Services Research (HSR), Human Immunodeficiency Virus (HIV), Racial and Ethnic Minorities, Racial and Ethnic Minorities, Screening
Macapagal K, Birkett M, Janulis P
HIV prevention fatigue and HIV treatment optimism among young men who have sex with men.
Young men who have sex with men (YMSM) and are at high risk for HIV completed measures of prevention fatigue, treatment optimism, HIV risk behaviors, and HIV-related knowledge and attitudes during a longitudinal study. Overall, YMSM reported low levels of HIV prevention fatigue and treatment optimism.
AHRQ-funded; HS000078.
Citation: Macapagal K, Birkett M, Janulis P .
HIV prevention fatigue and HIV treatment optimism among young men who have sex with men.
AIDS Educ Prev 2017 Aug;29(4):289-301. doi: 10.1521/aeap.2017.29.4.289.
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Keywords: Human Immunodeficiency Virus (HIV), Prevention, Risk
Derose KP, Payan DD, Fulcar MA
Factors contributing to food insecurity among women living with HIV in the Dominican Republic: a qualitative study.
The researchers examined factors contributing to food insecurity among women living with HIV (WLHIV) in the Dominican Republic (DR). Respondents identified economic instability as the primary driver of food insecurity, precipitated by enacted stigma in the labor and social domains. Women described experiences of HIV-related labor discrimination in formal and informal sectors.
AHRQ-funded; HS000046.
Citation: Derose KP, Payan DD, Fulcar MA .
Factors contributing to food insecurity among women living with HIV in the Dominican Republic: a qualitative study.
PLoS One 2017 Jul 25;12(7):e0181568. doi: 10.1371/journal.pone.0181568.
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Keywords: Human Immunodeficiency Virus (HIV), Nutrition, Patient Safety, Social Stigma, Social Determinants of Health
Muzaale AD, Althoff KN, Sperati CJ
Risk of end-stage renal disease in HIV-positive potential live kidney donors.
New federal regulations allow HIV-positive individuals to be live kidney donors; however, potential candidacy for donation is poorly understood given the increased risk of end-stage renal disease (ESRD) associated with HIV infection. To better understand this risk, the investigators compared the incidence of ESRD among 41 968 HIV-positive participants of North America AIDS Cohort Collaboration on Research and Design with the incidence of ESRD among comparable HIV-negative participants of National Health and Nutrition Examination III.
AHRQ-funded; 90047713.
Citation: Muzaale AD, Althoff KN, Sperati CJ .
Risk of end-stage renal disease in HIV-positive potential live kidney donors.
Am J Transplant 2017 Jul;17(7):1823-32. doi: 10.1111/ajt.14235..
Keywords: Kidney Disease and Health, Human Immunodeficiency Virus (HIV), Kidney Disease and Health
Turan B, Hatcher AM, Weiser SD
Framing mechanisms linking HIV-related stigma, adherence to treatment, and health outcomes.
The authors present a conceptual framework that highlights how unique dimensions of individual-level HIV-related stigma (perceived community stigma, experienced stigma, internalized stigma, and anticipated stigma) might differently affect the health of those living with HIV. Their conceptual framework posits that, in the context of intersectional and structural stigmas, individual-level dimensions of HIV-related stigma operate through interpersonal factors, mental health, psychological resources, and biological stress pathways.
AHRQ-funded; HS013852.
Citation: Turan B, Hatcher AM, Weiser SD .
Framing mechanisms linking HIV-related stigma, adherence to treatment, and health outcomes.
Am J Public Health 2017 Jun;107(6):863-69. doi: 10.2105/ajph.2017.303744.
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Keywords: Human Immunodeficiency Virus (HIV), Medication, Patient Adherence/Compliance, Patient-Centered Outcomes Research, Social Stigma
Liu P, Dillingham R, McManus K
Hospital days attributable to immune reconstitution inflammatory syndrome in persons living with HIV before and after the 2012 DHHS HIV guidelines.
The researchers’objectives were to quantify hospital usage attributable to Immune reconstitution inflammatory syndrome (IRIS) and assess the reasons for hospitalization in persons living with HIV (PLWH) before and after the guideline update. In their single-center study, there was a lower number of IRIS-attributable hospitalizations and IRIS-attributable hospital days in Time Period 2 compared with Time Period 1.
AHRQ-funded; HS024196.
Citation: Liu P, Dillingham R, McManus K .
Hospital days attributable to immune reconstitution inflammatory syndrome in persons living with HIV before and after the 2012 DHHS HIV guidelines.
AIDS Res Ther 2017 May 2;14:25. doi: 10.1186/s12981-017-0152-0.
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Keywords: Guidelines, Hospitalization, Human Immunodeficiency Virus (HIV)
Adamson BJS, Carlson JJ, Kublin JG
The potential cost-effectiveness of pre-exposure prophylaxis combined with HIV vaccines in the United States.
This economic evaluation found that at current prices, pre-exposure prophylaxis (PrEP) was not cost-effective alone or in combination. A combination strategy had the greatest health benefit but was not cost-effective as compared to vaccination alone. Vaccine durability and PrEP drug prices were key drivers of cost-effectiveness.
AHRQ-funded; HS013853.
Citation: Adamson BJS, Carlson JJ, Kublin JG .
The potential cost-effectiveness of pre-exposure prophylaxis combined with HIV vaccines in the United States.
Vaccines 2017 May 24;5(2). doi: 10.3390/vaccines5020013.
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Keywords: Human Immunodeficiency Virus (HIV), Vaccination, Healthcare Costs, Prevention
Cho H, Iribarren S, Schnall R
Technology-mediated interventions and quality of life for persons living with HIV/AIDS. A systematic review.
The aim of this review was to assess the impact of technology-mediated interventions on quality of life (QoL) and to identify the instruments used to measure the QoL of persons living with HIV/AIDS (PLWH). It identified four types of technology-mediated interventions and two types of QoL instruments used to examine the impact of technology-mediated interventions on PLWH. However, the evidence to support the improvement of QoL using technology-mediated interventions was insufficient.
AHRQ-funded; HS023963.
Citation: Cho H, Iribarren S, Schnall R .
Technology-mediated interventions and quality of life for persons living with HIV/AIDS. A systematic review.
Appl Clin Inform 2017 Apr 12;8(2):348-68. doi: 10.4338/aci-2016-10-r-0175.
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Keywords: Evidence-Based Practice, Human Immunodeficiency Virus (HIV), Patient-Centered Outcomes Research, Quality of Life
Eaton EF, Hudak K, Muzny CA
Budgetary impact of compliance with STI screening guidelines in persons living with HIV.
The study objective was to evaluate the budgetary impact of sexually transmitted infection (STI) screening. At one HIV clinic where the number of patients receiving care from August 2014 to August 2015 was 3,163, the study found that annual screening for N. gonorrhoeae, C. trachomatis, syphilis, and T. vaginalis would lead to a mean net loss of $129,416, $118,304, $72,625, and $13,523, respectively.
AHRQ-funded; HS013852; HS023009.
Citation: Eaton EF, Hudak K, Muzny CA .
Budgetary impact of compliance with STI screening guidelines in persons living with HIV.
J Acquir Immune Defic Syndr 2017 Mar;74(3):303-08. doi: 10.1097/qai.0000000000001212.
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Keywords: Human Immunodeficiency Virus (HIV), Guidelines, Screening, Sexual Health
Tucker JS, Shadel WG, Galvan FH
Pilot evaluation of a brief intervention to improve nicotine patch adherence among smokers living with HIV/AIDS.
This article presents results from a pilot evaluation of a brief smoking cessation treatment to improve adherence to the nicotine patch among Latino smokers living with HIV/AIDS. Although this small pilot was conducted to estimate effect sizes and was not powered to detect group differences, results were promising and suggested that adding a 10-min module focused on nicotine patch adherence to a standard 5 As protocol could increase abstinence rates.
AHRQ-funded; HS000062.
Citation: Tucker JS, Shadel WG, Galvan FH .
Pilot evaluation of a brief intervention to improve nicotine patch adherence among smokers living with HIV/AIDS.
Psychol Addict Behav 2017 Mar;31(2):148-53. doi: 10.1037/adb0000221.
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Keywords: Human Immunodeficiency Virus (HIV), Patient Adherence/Compliance, Racial and Ethnic Minorities, Tobacco Use
Schnall R, Cho H, Webel A
Predictors of willingness to use a smartphone for research in underserved persons living with HIV.
The purpose of this study was to assess factors associated with persons living with HIV (PLVH) for participation in research using smartphones. It concluded that future mHealth interventions targeting PLWH should take into account the inverse relationship between smartphone use and age, HIV stigma, and social isolation, and other predictor variables.
AHRQ-funded; HS023963.
Citation: Schnall R, Cho H, Webel A .
Predictors of willingness to use a smartphone for research in underserved persons living with HIV.
Int J Med Inform 2017 Mar;99:53-59. doi: 10.1016/j.ijmedinf.2017.01.002.
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Keywords: Human Immunodeficiency Virus (HIV), Patient Self-Management, Social Stigma, Telehealth, Vulnerable Populations
Adamson B, Dimitrov D, Devine B
The potential cost-effectiveness of HIV vaccines: a systematic review.
The aim of this paper was to review and compare HIV vaccine uncertainty in model, methodology, and parameterization. Model assumptions about vaccine price, HIV treatment costs, epidemic context, and willingness to pay influenced results more consistently than assumptions on HIV transmission dynamics.
AHRQ-funded; HS013853.
Citation: Adamson B, Dimitrov D, Devine B .
The potential cost-effectiveness of HIV vaccines: a systematic review.
Pharmacoeconom Open 2017 Mar;1(1):1-12. doi: 10.1007/s41669-016-0009-9.
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Keywords: Human Immunodeficiency Virus (HIV), Healthcare Costs, Vaccination
Agwu AL, Fleishman JA, Mahiane G
AHRQ Author: Fleishman JA
Comparing longitudinal CD4 responses to cART among non-perinatally HIV-infected youth versus adults: results from the HIVRN Cohort.
This study compared combination antiretroviral therapy (cART). outcomes over time following cART initiation between ART-naive non-perinatally HIV-infected (nPHIV) youth (13-24 years-old) and adults (>/=25-44 years-old). It found that despite having residual thymic tissue, youth attain similar, not superior, CD4 (T-lymphocyte cells) gains as adults.
AHRQ-authored.
Citation: Agwu AL, Fleishman JA, Mahiane G .
Comparing longitudinal CD4 responses to cART among non-perinatally HIV-infected youth versus adults: results from the HIVRN Cohort.
PLoS One 2017 Feb 9;12(2):e0171125. doi: 10.1371/journal.pone.0171125.
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Keywords: Human Immunodeficiency Virus (HIV), Outcomes, Medication
Morales-Aleman MM, Opoku J, Murray A
Disparities in retention in HIV care among HIV-infected young men who have sex with men in the District of Columbia, 2013.
Among young men who have sex with men (YMSM), aged 13-24 years, Blacks/African Americans and Hispanics/Latinos are disproportionately affected by HIV. This study analyzed surveillance data from the District of Columbia to examine care retention among YMSM living with HIV infection. They found that retention in HIV care was suboptimal for YMSM and indicated that increased retention efforts are warranted to improve outcomes and reduce age and racial/ethnic disparities.
AHRQ-funded; HS013852.
Citation: Morales-Aleman MM, Opoku J, Murray A .
Disparities in retention in HIV care among HIV-infected young men who have sex with men in the District of Columbia, 2013.
LGBT Health 2017 Feb;4(1):34-41. doi: 10.1089/lgbt.2016.0126..
Keywords: Disparities, Human Immunodeficiency Virus (HIV), Patient-Centered Healthcare, Young Adults
Schneider JA, Kozloski M, Michaels S
Criminal justice involvement history is associated with better HIV care continuum metrics among a population-based sample of young black MSM.
This study examined how history of criminal justice involvement (CJI) is related to HIV care continuum metrics among young black MSM 16-29 years of age. It found that having one CJI experience and detention for only 1 day was associated with better retention in care compared with no or more frequent CJI. Those with a previous history of CJI were more successful in achieving most HIV care continuum metrics.
AHRQ-funded; HS000084.
Citation: Schneider JA, Kozloski M, Michaels S .
Criminal justice involvement history is associated with better HIV care continuum metrics among a population-based sample of young black MSM.
AIDS 2017 Jan 2;31(1):159-65. doi: 10.1097/qad.0000000000001269.
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Keywords: Care Management, Human Immunodeficiency Virus (HIV), Patient Adherence/Compliance, Racial and Ethnic Minorities