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Research Studies is a monthly compilation of research articles funded by AHRQ or authored by AHRQ researchers and recently published in journals or newsletters.
Results1 to 25 of 143 Research Studies Displayed
AHRQ Author: Huppert J
Adolescents with vulvar ulcers: COVID-19 disease, COVID-19 vaccines, and the value of case reports.
The author indicates that there are too few cases reporting aphthosis after COVID disease or COVID-19 vaccination to infer a statistical association, but that case reports are a valuable source of rich details about conditions that are difficult to study with more rigorous designs and can be synthesized to help guide medical care. She recommends that it is time for a high-quality systematic review of vulvar aphthosis in order for clinicians to incorporate the existing evidence into decision-making and best care for patients.
Citation: Huppert J . Adolescents with vulvar ulcers: COVID-19 disease, COVID-19 vaccines, and the value of case reports. J Pediatr Adolesc Gynecol 2022 Apr;35(2):109-11. doi: 10.1016/j.jpag.2022.01.006..
Keywords: Children/Adolescents, COVID-19, Vaccination, Research Methodologies
Chu DK, Abrams EM, Golden BK
Risk of second allergic reaction to SARS-CoV-2 vaccines: a systematic review and meta-analysis.
The purpose of this systematic review and meta-analysis of case studies and case reports was to assess the risk of severe immediate allergic reactions to a second dose of SARS-CoV-2 mRNA vaccine in people who experienced an immediate allergic reaction to the first dose. The researchers evaluated the World Health Organization Global Coronavirus database, Web of Science, MEDLINE, and Embase from the date of inception through October 4th, 2021. The main outcomes and measures were a risk of severe immediate allergic reaction and repeated severe immediate allergic reactions with a second vaccine dose. The study found that among 22 studies of SARS-CoV-2 mRNA vaccines, 1366 individuals had immediate allergic reactions to their first vaccination. Of these, 87.8% were women with a mean age of 46.1 years. Six patients developed severe immediate allergic reactions after their second vaccination, 232 developed mild symptoms, and 1360 tolerated the dose. Among 78 persons with severe immediate allergic reactions to their first SARS-CoV-2 mRNA vaccination, 4 people had a second severe immediate reaction, and 15 had non-severe symptoms. There were no deaths. The study concluded that in a supervised setting equipped to manage severe allergic reactions, revaccination of individuals with an immediate allergic reaction to a first SARS-CoV-2 mRNA vaccine dose can be safe.
Citation: Chu DK, Abrams EM, Golden BK . Risk of second allergic reaction to SARS-CoV-2 vaccines: a systematic review and meta-analysis. JAMA Intern Med 2022 Apr;182(4):376-85. doi: 10.1001/jamainternmed.2021.8515..
Keywords: COVID-19, Vaccination, Risk, Evidence-Based Practice, Patient-Centered Outcomes Research
Choi K, Becerra-Culqui T, Bhakta B
Parent intentions to vaccinate children with autism spectrum disorder against COVID-19.
This study’s purpose was to investigate associations between parent vaccine confidence and intentions to have their child with autism vaccinated with the COVID-19 vaccine. A cross-sectional, web-based survey of 332 parents of children with autism spectrum disorder who were members of an integrated healthcare system in Southern California was conducted from May to July 2021. Approximately 35% of parents were going to vaccinate their child against COVID-19. Positive vaccine beliefs, healthcare provider trust, or parent vaccination status were associated with intention to vaccinate.
Citation: Choi K, Becerra-Culqui T, Bhakta B . Parent intentions to vaccinate children with autism spectrum disorder against COVID-19. J Pediatr Nurs 2022 Mar-Apr;63:108-10. doi: 10.1016/j.pedn.2021.11.019..
Keywords: Children/Adolescents, COVID-19, Vaccination, Autism, Chronic Conditions
Qin CX, Auerbach SR, Charnaya O
Antibody response to 2-dose SARS-CoV-2 mRNA vaccination in pediatric solid organ transplant recipients.
While many adult solid organ transplant recipients (SOTRs) have impaired antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination, pediatric SOTRs’ response has not been assessed. In this article, the researchers reported the immunogenicity and safety of BNT162b2 mRNA vaccination in pediatric SOTRs.
Citation: Qin CX, Auerbach SR, Charnaya O . Antibody response to 2-dose SARS-CoV-2 mRNA vaccination in pediatric solid organ transplant recipients. Am J Transplant 2022 Feb;22(2):669-72. doi: 10.1111/ajt.16841..
Keywords: Children/Adolescents, Vaccination, COVID-19, Transplantation
Bastani R, Glenn BA, Singhal R
Increasing HPV vaccination among low-income, ethnic minority adolescents: effects of a multicomponent system intervention through a county health department hotline.
The human papillomavirus (HPV) vaccine has cancer prevention benefits, yet low uptake. The purpose of the study was to evaluate an intervention intended to improve vaccine uptake in low-income, ethnic minority adolescents using a telephone hotline to seek county health department services. The researchers recruited participants through randomization of health department hotline callers who were caregivers of never-vaccinated adolescents aged 11-17. The intervention included multi-lingual print and telephone education and personalized referral to a low cost or free provider of vaccines. Participants completed baseline, 3-month, and 9-month telephone surveys. The study found that by the end of the 9-month follow up period, the HPV vaccination rates had increased, however there were no differences between the intervention (45%) and control (42%) groups. The researchers also observed significant improvements in perceived HPV knowledge, perceived HPV risk, and barriers to vaccination. The study concluded that the county hotline intervention did not produce a greater increase in HPV vaccine rates in the intervention group than the group without the intervention. The study authors recommend that future studies should evaluate interventions which are more intensive and address accessing and using services in complex, safety net settings. The authors also noted that because 44% of unvaccinated adolescents in both the intervention and control groups received at least one dose of the vaccine during the study period, investigators of future studies should be aware of the potential priming effects of participation in the study, which may impact the results of interventions.
Citation: Bastani R, Glenn BA, Singhal R . Increasing HPV vaccination among low-income, ethnic minority adolescents: effects of a multicomponent system intervention through a county health department hotline. Cancer Epidemiol Biomarkers Prev 2022 Jan;31(1):175-82. doi: 10.1158/1055-9965.Epi-20-1578..
Keywords: Children/Adolescents, Vaccination, Low-Income, Racial / Ethnic Minorities, Sexual Health, Prevention
Koo G, Anvari S, Friedman DL
mRNA COVID-19 vaccine safety in patients with previous immediate hypersensitivity to pegaspargase.
The authors sought to understand the safety of PEG2000-containing mRNA COVID vaccines in patients who reported a label of immediate pegaspargase hypersensitivity. They found that all 19 studied patients tolerated their first dose of Pfizer-BioNTech SARS-CoV-2 vaccine with no symptoms. Subsequently, all 19 patients tolerated their second doses uneventfully as well.
Citation: Koo G, Anvari S, Friedman DL . mRNA COVID-19 vaccine safety in patients with previous immediate hypersensitivity to pegaspargase. J Allergy Clin Immunol Pract 2022 Jan;10(1):322-25. doi: 10.1016/j.jaip.2021.09.051..
Keywords: COVID-19, Vaccination
Oster NV, Williams EC, Unger JM
A risk prediction model to identify newborns at risk for missing early childhood vaccinations.
Approximately 30% of US children aged 24 months have not received all recommended vaccines. This retrospective cohort study aimed to develop a prediction model to identify newborns at high risk for missing early childhood vaccines. The investigators concluded that their prediction model using information readily available in birth hospitalization records consistently identified newborns at high risk for undervaccination.
Citation: Oster NV, Williams EC, Unger JM . A risk prediction model to identify newborns at risk for missing early childhood vaccinations. J Pediatric Infect Dis Soc 2021 Dec 31;10(12):1080-86. doi: 10.1093/jpids/piab073..
Keywords: Newborns/Infants, Vaccination, Risk
Feldman AG, O'Leary ST, Danziger-Isakov L
The risk of resurgence in vaccine-preventable infections due to coronavirus disease 2019-related gaps in immunization.
This paper discusses the decline in immunization delivery during the COVID-19 pandemic. The global community is at risk for a resurgence in vaccine-preventable infections including measles, pertussis, and polio. Outbreaks in the United States are likely to occur when social distancing stops and children return to school. Partnerships between healthcare providers, community leaders, and local, state, regional, and national public health departments are needed to reassure families that vaccine delivery during COVID-19 is safe as well as to identify and catch up those children who are under-immunized.
Citation: Feldman AG, O'Leary ST, Danziger-Isakov L . The risk of resurgence in vaccine-preventable infections due to coronavirus disease 2019-related gaps in immunization. Clin Infect Dis 2021 Nov 16;73(10):1920-23. doi: 10.1093/cid/ciab127..
Keywords: COVID-19, Children/Adolescents, Vaccination, Infectious Diseases
Cox SN, Wedlock PT, Pallas SW
A systems map of the economic considerations for vaccination: application to hard-to-reach populations.
The authors developed a systems map of the mechanisms involved in vaccination, and associated costs and benefits, focused at the service delivery level, in order to identify the mechanisms that may be different for hard-to-reach populations. They concluded that decision-makers can use this systems map to understand where steps in the vaccination process may be interrupted or weak and identify where gaps exist in the understanding of the economics of vaccination. With improved understanding of system-wide effects, their map can help decision-makers inform targeted interventions and policies to increase vaccination coverage in hard-to-reach populations.
AHRQ-funded; HS023317; HS028165.
Citation: Cox SN, Wedlock PT, Pallas SW . A systems map of the economic considerations for vaccination: application to hard-to-reach populations. Vaccine 2021 Nov 5;39(46):6796-804. doi: 10.1016/j.vaccine.2021.05.033..
Keywords: Vaccination, Healthcare Costs
Krantz MS, Stone CA, Rolando LA
An academic hospital experience screening mRNA COVID-19 vaccine risk using patient allergy history.
This retrospective cohort study examined the outcomes of screening mRNA COVID-19 vaccine risk using patient-reported anaphylactic history at a single academic hospital employee vaccination program. Although rare, m-RNA COVID-19 vaccines have been contraindicated in patients with known allergy to polyethylene glycol (PEG) 2000 present in the lipid nanoparticle carrier system of these vaccines. Health care workers and other affiliates who met criteria based on the Tennessee Department of Health COVID-19 Vaccination Plan received the first dose of Pfizer m-RNA vaccine. Out of 23,035 individuals who were screened before dose 1, 31 reported a high-risk allergy history that triggered a focused review by the Allergist On-Call. Out of those 31, only 3 were recommended not to proceed to Dose 1 and were referred to the Drug Allergy Clinic for assessment. Ultimately, all individuals were cleared to receive their first dose, and none reported an adverse reaction.
Citation: Krantz MS, Stone CA, Rolando LA . An academic hospital experience screening mRNA COVID-19 vaccine risk using patient allergy history. J Allergy Clin Immunol Pract 2021 Oct;9(10):3807-10. doi: 10.1016/j.jaip.2021.07.010..
Keywords: COVID-19, Screening, Vaccination
Bartsch SM, Wedlock PT, O'Shea KJ
Lives and costs saved by expanding and expediting coronavirus disease 2019 vaccination.
The authors developed a computational model representing the United States population, COVID-19 coronavirus spread (February 2020-December 2022), and vaccination to determine the impact of increasing coverage and expediting time to achieve coverage. They concluded that their study quantified the potential value of decreasing vaccine hesitancy and increasing vaccination coverage and how this value may decrease with the time it takes to achieve coverage, emphasizing the need to reach high coverage levels as soon as possible, especially before the fall/winter.
Citation: Bartsch SM, Wedlock PT, O'Shea KJ . Lives and costs saved by expanding and expediting coronavirus disease 2019 vaccination. J Infect Dis 2021 Sep 17;224(6):938-48. doi: 10.1093/infdis/jiab233..
Keywords: COVID-19, Vaccination, Public Health
Hofstetter AM, Opel DJ, Stockwell MS
Associations between health care professional communication practices and influenza vaccination of hospitalized children.
The objective of this study was to describe the communication of health care professionals (HCPs) with parents of hospitalized children concerning the influenza vaccine. A survey was conducted online or via telephone with English- and Spanish-speaking parents of influenza vaccine-eligible children hospitalized at a pediatric hospital after discharge. Findings showed that a parent-reported HCP conversation and recommendation were associated with influenza vaccination during hospitalization.
Citation: Hofstetter AM, Opel DJ, Stockwell MS . Associations between health care professional communication practices and influenza vaccination of hospitalized children. Acad Pediatr 2021 Sep-Oct;21(7):1142-50. doi: 10.1016/j.acap.2021.06.014..
Keywords: Children/Adolescents, Influenza, Vaccination, Communication, Health Promotion, Clinician-Patient Communication
Dutta S, McEvoy DS, Stump T
Clinical decision support reduces unnecessary tetanus vaccinations in the emergency department.
The authors implemented a clinical decision support alert in the electronic health record that warned providers when ordering a tetanus vaccine if a prior one had been given within 10 years and studied its efficacy to reduce potentially unnecessary vaccines in the ED. They found that a clinical decision support alert that warns ED clinicians that a patient may have an up-to-date tetanus vaccination status reduced potentially unnecessary vaccinations.
Citation: Dutta S, McEvoy DS, Stump T . Clinical decision support reduces unnecessary tetanus vaccinations in the emergency department. Ann Emerg Med 2021 Sep;78(3):370-80. doi: 10.1016/j.annemergmed.2021.02.021..
Keywords: Clinical Decision Support (CDS), Decision Making, Vaccination, Health Information Technology (HIT)
Holaday LW, Balasuriya L, Roy B
Medicare beneficiaries' plans for the COVID-19 vaccine in Fall 2020, and why some planned to decline.
This study uses data from a survey of Medicare beneficiaries conducted in the fall of 2020 before the COVID-19 vaccine was approved to try and predict COVID-19 vaccine acceptance and decline rates. A cross-sectional analysis using the Medicare Current Beneficiary Survey (MCBS) Fall COVID-19 Supplement was used to conduct telephone interviews administered by NORC at the University of Chicago. The analysis included 8,455 community-dwelling Medicare beneficiaries, representative of 50.2 million people. Overall, 58.7% said they would get the vaccine, 15.3% said they would not, and 26.1% were unsure. Least likely to say they would get a vaccine were beneficiaries under 65 years old (48.8%), Black beneficiaries (36.2%) and Hispanic beneficiaries (50.5%). Reasons given for not planning to get vaccinated included 1) the vaccine could have side effects or is not safe (42.4%), 2) do not trust what the government says about the vaccine (42.4%), 3) do not think the vaccine would prevent COVID-19 (11.%), and 4) do not like vaccines or needles (8.2%). Black and Hispanic beneficiaries were more likely to say they were declining because they don’t trust the government than White beneficiaries. Younger beneficiaries were more likely to say the vaccine could cause COVID-19, and only 2% of respondents said they would decline the vaccine because COVID-19 is not serious. The latter group was disproportionately male (77.5%) and White (94.5%).
AHRQ-funded; HS022882; HS025164.
Citation: Holaday LW, Balasuriya L, Roy B . Medicare beneficiaries' plans for the COVID-19 vaccine in Fall 2020, and why some planned to decline. J Am Geriatr Soc 2021 Sep;69(9):2434-37. doi: 10.1111/jgs.17285..
Keywords: COVID-19, Vaccination, Medicare
Khorasani SB, Koutoujian PJ, Zubiago J
COVID-19 vaccine interest among corrections officers and people who are incarcerated at Middlesex County jail, Massachusetts.
The Middlesex [Massachusetts] Sheriff’s Office developed and distributed two self-response surveys to assess COVID-19 vaccine willingness among people incarcerated in the jail and among people who work at the jail. The goal of this study was to characterize vaccine willingness in these two populations at the Middlesex House of Correction and Jail. Findings showed that 59% of people incarcerated in jail did not want the COVID-19 vaccine, while 82% of jail staff were interested in receiving the vaccine. Among people who were incarcerated, those who identified as Black had significantly decreased odds of wanting the vaccine compared to those who identified as white. Race was not significantly associated with vaccine willingness among jail employees when adjusting for role and gender.
Citation: Khorasani SB, Koutoujian PJ, Zubiago J . COVID-19 vaccine interest among corrections officers and people who are incarcerated at Middlesex County jail, Massachusetts. J Urban Health 2021 Aug;98(4):459-63. doi: 10.1007/s11524-021-00545-y..
Keywords: COVID-19, Vaccination, Vulnerable Populations
Caballero ML, Krantz MS, Quirce S
Hidden dangers: recognizing excipients as potential causes of drug and vaccine hypersensitivity reactions.
In this paper, the authors provided a review of the evidence-based literature outlining epidemiology and mechanisms of excipient reactions and provided strategies for heightened recognition and allergy testing.
Citation: Caballero ML, Krantz MS, Quirce S . Hidden dangers: recognizing excipients as potential causes of drug and vaccine hypersensitivity reactions. J Allergy Clin Immunol Pract 2021 Aug;9(8):2968-82. doi: 10.1016/j.jaip.2021.03.002..
Keywords: Adverse Drug Events (ADE), Adverse Events, Medication, Medication: Safety, Vaccination, Patient Safety
Hofstetter AM, Opel DJ, Stockwell MS
Influenza-related knowledge, beliefs, and experiences among caregivers of hospitalized children.
Caregivers frequently decline influenza vaccine for their hospitalized child. In this study, the investigators aimed to examine factors impacting their influenza vaccine decision-making. The investigators conducted a cross-sectional survey study of English- and Spanish-speaking caregivers of children hospitalized at a tertiary care pediatric hospital between November 2017 and April 2018.They identified key factors impacting influenza vaccine decision-making among caregivers of hospitalized children, a critical step to improving uptake in this population.
Citation: Hofstetter AM, Opel DJ, Stockwell MS . Influenza-related knowledge, beliefs, and experiences among caregivers of hospitalized children. Hosp Pediatr 2021 Aug;11(8):815-32. doi: 10.1542/hpeds.2020-003459..
Keywords: Children/Adolescents, Caregiving, Influenza, Vaccination
Orenstein EW, ElSayed-Ali O, Kandaswamy S
Evaluation of a clinical decision support strategy to increase seasonal influenza vaccination among hospitalized children before inpatient discharge.
The authors’ goal was to design and evaluate a clinical decision support (CDS) strategy to increase the proportion of eligible hospitalized children who receive a seasonal influenza vaccine prior to inpatient discharge. They found that a user-centered CDS may be associated with significantly improved influenza vaccination rates among hospitalized children.
Citation: Orenstein EW, ElSayed-Ali O, Kandaswamy S . Evaluation of a clinical decision support strategy to increase seasonal influenza vaccination among hospitalized children before inpatient discharge. JAMA Netw Open 2021 Jul;4(7):e2117809. doi: 10.1001/jamanetworkopen.2021.17809..
Keywords: Children/Adolescents, Influenza, Vaccination, Clinical Decision Support (CDS), Health Information Technology (HIT), Hospital Discharge
Glenn BA, Nonzee NJ, Tieu L
Human papillomavirus (HPV) vaccination in the transition between adolescence and adulthood.
This study looked at the barriers to human papillomavirus (HPV) vaccination among young adults receiving care at the student health center of a large public university. The authors conducted semi-structured interviews (n=27) and four focus groups with undergraduate and graduate students (n=18) and semi-structured interviews with 6 health care providers. The interviews and focus groups explored perceived risk of HPV infection, benefits of the HPV vaccine, and motivations for and barriers to HPV vaccination. Many students cited their parents’ views and recommendations from their medical providers as influential on their decision-making process. Cervical cancer prevention was considered the main benefit of the HPV vaccine and sexual activity was a risk factor for HPV infection. Students often lacked knowledge about the vaccine’s benefit for males. Safety and side effects of the vaccine perceived as new were also cited. Providers’ vaccine recommendations were impacted by health system factors including clinical infrastructure, office visit priorities, and processes for recommending and documentation vaccination. Providers suggested various promotion strategies including improving the timing and messaging of outreach efforts on campus and bolstering clinical infrastructure.
Citation: Glenn BA, Nonzee NJ, Tieu L . Human papillomavirus (HPV) vaccination in the transition between adolescence and adulthood. Vaccine 2021 Jun 8;39(25):3435-44. doi: 10.1016/j.vaccine.2021.04.019..
Keywords: Young Adults, Sexual Health, Infectious Diseases, Vaccination, Prevention, Cancer: Cervical Cancer, Cancer, Women
Hofstetter AM, Schaffer S
Childhood and adolescent vaccination in alternative settings.
This article reviews the unique advantages, challenges, and experiences regarding vaccine delivery in alternative settings, such as schools, emergency rooms, hospitals, and pharmacies. It describes the key components that each setting must possess as well as other important factors to consider when assessing the ability of each to deliver vaccines to the children and adolescents they serve. It is important to emphasize that these settings should not replace the medical home as the primary location for vaccination, but rather serve as a critical safety net for high-risk individuals and communities and in situations where access to traditional locations may be limited, such as during the COVID-19 pandemic.
Citation: Hofstetter AM, Schaffer S . Childhood and adolescent vaccination in alternative settings. Acad Pediatr 2021 May-Jun;21(4s):S50-s56. doi: 10.1016/j.acap.2021.02.001..
Keywords: Children/Adolescents, Vaccination, Healthcare Delivery, Public Health
Bartsch SM, O'Shea KJ, Wedlock PT
The benefits of vaccinating with the first available COVID-19 coronavirus vaccine.
This study’s objective was to determine quantitatively the benefits of early vaccination for COVID-19 even if later on in the pandemic a latter vaccine has substantially higher efficacy. The team developed this model in 2020 before vaccinations became available. For example if a vaccine with 50% efficacy becomes available when 10% of the population has already been infected, waiting until 40% of the population are infected for a vaccine with 80% efficacy results in 15.6 million additional cases and 1.5 million additional hospitalizations, costing $20.6 billion more in direct medical costs and $12.4 billion more in productivity losses.
Citation: Bartsch SM, O'Shea KJ, Wedlock PT . The benefits of vaccinating with the first available COVID-19 coronavirus vaccine. Am J Prev Med 2021 May;60(5):605-13. doi: 10.1016/j.amepre.2021.01.001..
Keywords: COVID-19, Vaccination, Healthcare Costs, Prevention, Infectious Diseases
Teixeira da Silva D, Biello K, Lin WY
COVID-19 vaccine acceptance among an online sample of sexual and gender minority men and transgender women.
Sexual and gender minority (SGM) populations are particularly vulnerable to poor COVID-19 outcomes and are more likely to experience stigma and medical mistrust that may impact COVID-19 vaccine acceptance. This study examined the prevalence of COVID testing and diagnosis and assessed COVID-19 vaccine acceptance among a large sample of SGM. The investigators found that black participants were significantly less likely to accept a COVID-19 vaccine, and Asian participants were significantly more likely to accept a vaccine, compared to White peers.
Citation: Teixeira da Silva D, Biello K, Lin WY . COVID-19 vaccine acceptance among an online sample of sexual and gender minority men and transgender women. Vaccines 2021 Mar;9(3). doi: 10.3390/vaccines9030204..
Keywords: Vaccination, COVID-19, Public Health, Racial / Ethnic Minorities, Vulnerable Populations
Bartsch SM, O'Shea KJ, Wedlock PT
Potential clinical and economic value of norovirus vaccination in the community setting.
This paper examined the potential clinical and economic value of norovirus vaccination in a community setting using a transmission, clinical, and economics computation simulation model representing different U.S. population segments. The simulation looked at the impact of vaccinating children <5 years and older adults aged 65 and older. Compared with no vaccine, vaccinating preschool-aged children averted 8-7% of symptomatic norovirus cases in a community and vaccinating older adults averted 2-29% of symptomatic cases. Vaccination with a 25% vaccine efficacy was cost effective when vaccinations cost ≤$445 and cost saving at ≤$370 when vaccinating preschool-aged children and ≤$42 and ≤$30, respectively for older adults. With 50% efficacy, vaccination was cost effective when it cost ≤$1,190 and cost saving at ≤$930 when vaccinating preschool-aged children and ≤$110 and ≤$64, respectively, for older adults. At 75% vaccine efficacy the cost thresholds increased to ≤$1,600 and ≤$1,300 for preschool-aged children and ≤$165 and ≤$100 for older adults.
Citation: Bartsch SM, O'Shea KJ, Wedlock PT . Potential clinical and economic value of norovirus vaccination in the community setting. Am J Prev Med 2021 Mar;60(3):360-68. doi: 10.1016/j.amepre.2020.10.022..
Keywords: Infectious Diseases, Vaccination, Healthcare Costs, Value
Fisher KA, Bloomstone SJ, Walder J
Attitudes toward a potential SARS-CoV-2 vaccine: a survey of U.S. adults.
The authors assessed the intent to be vaccinated against COVID-19 among a representative sample of adults in the United States and identified predictors of and reasons for vaccine hesitancy. They found that approximately 3 in 10 adults were not sure they would accept vaccination and 1 in 10 did not intend to be vaccinated against COVID-19. They recommended targeted and multipronged efforts to increase acceptance of a COVID-19 vaccine.
Citation: Fisher KA, Bloomstone SJ, Walder J . Attitudes toward a potential SARS-CoV-2 vaccine: a survey of U.S. adults. Ann Intern Med 2020 Dec 15;173(12):964-73. doi: 10.7326/m20-3569..
Keywords: COVID-19, Vaccination, Public Health, Patient Adherence/Compliance
Chabra S, Hofstetter AM
Timely hepatitis B birth dose receipt for newborns: within 24 hours.
In this paper, the authors discuss the importance of timely administration of the hepatitis B birth dose to achieve the national goal of zero perinatal hepatitis B transmission in the near future. They state that the necessity of capturing vaccination opportunities in diverse health care settings is clearly evident during the coronavirus pandemic.
Citation: Chabra S, Hofstetter AM . Timely hepatitis B birth dose receipt for newborns: within 24 hours. Hosp Pediatr 2020 Dec;10(12):e18-e20. doi: 10.1542/hpeds.2020-001255..
Keywords: Newborns/Infants, Hepatitis, Vaccination