National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
126 to 150 of 237 Research Studies DisplayedMoise N, Shah RN, Essock S
Sustainability of collaborative care management for depression in primary care settings with academic affiliations across New York State.
This study examined sustainability of collaborative care management for depression in primary care settings with academic affiliations across New York State. The investigators used descriptive statistics to assess implementation metrics in sustaining vs. opt-out clinics and trends in implementation fidelity 1 and 2 years into the sustainability phase among sustaining clinics.
AHRQ-funded; HS025198
Citation: Moise N, Shah RN, Essock S .
Sustainability of collaborative care management for depression in primary care settings with academic affiliations across New York State.
Implement Sci 2018 Oct 12;13(1):128. doi: 10.1186/s13012-018-0818-6..
Keywords: Care Coordination, Depression, Behavioral Health, Primary Care
Blumenthal KG, Li Y, Acker WW
Multiple drug intolerance syndrome and multiple drug allergy syndrome: epidemiology and associations with anxiety and depression.
In this study, the authors used electronic health record (EHR) data to describe prevalences of MDIS and MDAS and to examine associations with anxiety and depression. The investigators concluded that: 1.) while 6% of patients had MDIS, only 1% had MDAS; 2.) MDIS was associated with both anxiety and depression; 3.) patients with both anxiety and depression had an almost twofold increased odds of MDIS; 4.) MDAS was associated with a 40% increased odds of depression, but there was no significant association with anxiety.
AHRQ-funded; HS022728.
Citation: Blumenthal KG, Li Y, Acker WW .
Multiple drug intolerance syndrome and multiple drug allergy syndrome: epidemiology and associations with anxiety and depression.
Allergy 2018 Oct;73(10):2012-23. doi: 10.1111/all.13440..
Keywords: Adverse Drug Events (ADE), Adverse Events, Anxiety, Depression, Electronic Health Records (EHRs), Health Information Technology (HIT), Medication, Behavioral Health, Patient Safety
Katz RB, Toprak M, Wilkinson ST
Concurrent use of ketamine and monoamine oxidase inhibitors in the treatment of depression: a letter to the editor.
This research letter describes the implications of concurrent use of ketamine and monoamine oxidase inhibitors (MAO-Is) in the treatment of depression. There have not been many studies examining this. A literature review was conducted and eight cases total were found. All but one did not experience cardiovascular adverse events and that on patient had comorbid cardiac history. While these results were promising, the authors stressed that it is still unknown if concurrent use is safe and further research is needed.
AHRQ-funded; HS023000.
Citation: Katz RB, Toprak M, Wilkinson ST .
Concurrent use of ketamine and monoamine oxidase inhibitors in the treatment of depression: a letter to the editor.
Gen Hosp Psychiatry 2018 Sep - Oct;54:62-64. doi: 10.1016/j.genhosppsych.2018.05.007..
Keywords: Adverse Drug Events (ADE), Medication, Depression, Behavioral Health
Simpkin AL, Khan A, West DC
Stress from uncertainty and resilience among depressed and burned out residents: a cross-sectional study.
This study examined how stress from uncertainty is related to resilience among medical residents and whether those attributes are related to depression and burnout. The investigators surveyed 86 residents in pediatric residency programs from 4 urban freestanding children’s hospitals in North America in 2015. They used the Physicians’ Reaction to Uncertainty Scale to measure stress from uncertainty, the 14-item Resilience Scale to measure uncertainty, the Harvard National Depression Scale for depression, and the Maslach Burnout Inventory for burnout. There was a response rate of 58.1%. Five residents met depression criteria, and 15 residents met the burnout criteria. Depressed and burned out residents both had higher mean levels of stress compared to residents who neither depressed nor burned out.
AHRQ-funded; HS022986.
Citation: Simpkin AL, Khan A, West DC .
Stress from uncertainty and resilience among depressed and burned out residents: a cross-sectional study.
Acad Pediatr 2018 Aug;18(6):698-704. doi: 10.1016/j.acap.2018.03.002..
Keywords: Burnout, Stress, Depression, Provider: Physician, Behavioral Health, Provider, Education: Continuing Medical Education, Hospitals
Srivatsan S, Guduguntla V, Young KZ
Clinical versus patient-reported measures of depression in bariatric surgery.
This study examined the relationship between traditional clinical screening tools and a novel patient-reported depression screening survey, Patient Health Questionnaire 8 (PHQ-8), in the setting of the bariatric surgery preoperative assessment. The researchers found a higher rate of clinically diagnosed depression in their cohort compared to the general population. However, when using the validated PHQ-8 survey, the rate of depression more closely approximated the national incidence.
AHRQ-funded; HS023621; HS024403.
Citation: Srivatsan S, Guduguntla V, Young KZ .
Clinical versus patient-reported measures of depression in bariatric surgery.
Surg Endosc 2018 Aug;32(8):3683-90. doi: 10.1007/s00464-018-6101-8..
Keywords: Depression, Patient Safety, Screening, Surgery
Yucel A, Essien EJ, Sanyal S
Racial/ethnic differences in the treatment of adolescent major depressive disorders (MDD) across healthcare providers participating in the Medicaid program.
The purpose of this study was to examine whether racial/ethnic differences in receipt of major depressive disorder (MDD) treatment could be explained by the specialty of provider diagnosing the adolescent. The investigators found that for adolescents with MDD, being first diagnosed by a psychiatrist was associated with higher treatment rate and reduced racial/ethnic variation in the utilization of pharmacotherapy.
AHRQ-funded; HS025251.
Citation: Yucel A, Essien EJ, Sanyal S .
Racial/ethnic differences in the treatment of adolescent major depressive disorders (MDD) across healthcare providers participating in the Medicaid program.
J Affect Disord 2018 Aug 1;235:155-61. doi: 10.1016/j.jad.2018.04.045..
Keywords: Access to Care, Depression, Disparities, Medicaid, Behavioral Health, Racial and Ethnic Minorities
Brunwasser SM, Freres DR, Gillham JE
Youth cognitive-behavioral depression prevention: testing theory in a randomized controlled trial.
This study tested the plausibility of a theoretical model of change for the Penn Resiliency Program (PRP), a cognitive-behavioral (CB) depression prevention program for adolescents. The authors assert that when effective, PRP's CB training provides incremental value over non-specific components and there are indirect effects on depressive symptoms through improvements in explanatory style.
AHRQ-funded; HS022990.
Citation: Brunwasser SM, Freres DR, Gillham JE .
Youth cognitive-behavioral depression prevention: testing theory in a randomized controlled trial.
Cognit Ther Res 2018 Aug;42(4):468-82..
Keywords: Children/Adolescents, Behavioral Health, Depression, Patient-Centered Healthcare, Prevention
Rhoten BA, Murphy BA, Dietrich MS
Depressive symptoms, social anxiety, and perceived neck function in patients with head and neck cancer.
This study examined the relationships of depressive symptoms and social anxiety with perceived neck function in patients treated for head and neck cancer. Significant associations were found between membership in the neck disability index trajectories and membership in the longitudinal patterns of depressive symptoms and social anxiety. The investigators concluded that impaired physical function and psychological distress are intertwined for patients with head and neck cancer long after completing treatment.
AHRQ-funded; HS022990.
Citation: Rhoten BA, Murphy BA, Dietrich MS .
Depressive symptoms, social anxiety, and perceived neck function in patients with head and neck cancer.
Head Neck 2018 Jul;40(7):1443-52. doi: 10.1002/hed.25129..
Keywords: Anxiety, Cancer, Depression, Behavioral Health
Yin S, Connolly Gibbons MB, Diehl C
A self-report version of the ways of responding: reliability and validity in a clinical sample.
This study evaluated the reliability and validity of a modified, self-report version of the Ways of Responding instrument measures (WOR-SR) in a community mental health sample with depressive symptoms. Subjects completed the WOR-SR and other measures of depressive symptoms, dysfunctional cognitions, functioning, quality of life, and interpersonal problems at multiple time points. The authors conclude from their results that the WOR-SR is a reliable and valid measure of compensatory skills in patients receiving treatment for depression at community mental health centers.
AHRQ-funded; HS022124; HS018440.
Citation: Yin S, Connolly Gibbons MB, Diehl C .
A self-report version of the ways of responding: reliability and validity in a clinical sample.
Psychother Res 2018 Jul;28(4):581-92. doi: 10.1080/10503307.2016.1233367..
Keywords: Depression, Diagnostic Safety and Quality, Behavioral Health, Outcomes
Hudson KE, Wolf SP, Samsa GP
The surprise question and identification of palliative care needs among hospitalized patients with advanced hematologic or solid malignancies.
Little is known about quality of life (QOL), depression, and end-of-life (EOL) outcomes among hospitalized patients with advanced cancer. The objective of this study was to assess whether a surprise question identified inpatients with advanced cancer likely to have unmet palliative care needs. The investigators indicated that hospitalized patients with advanced cancer may benefit from palliative care interventions to improve mood, QOL, and EOL care, and the surprise question is a practical method to identify those with unmet needs.
AHRQ-funded; HS023681.
Citation: Hudson KE, Wolf SP, Samsa GP .
The surprise question and identification of palliative care needs among hospitalized patients with advanced hematologic or solid malignancies.
J Palliat Med 2018 Jun;21(6):789-95. doi: 10.1089/jpm.2017.0509..
Keywords: Palliative Care, Cancer, Inpatient Care, Quality of Life, Depression, Behavioral Health
Levis B, Benedetti A, Riehm KE
Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews.
This study compared two interview methods that are used to diagnose depression in patients. It was found that the odds of diagnosing for depression were high for the Mini International Neuropsychiatric Interview (MINI) than the Composite International Diagnostic Interview (CIDI).
AHRQ-funded; HS018246.
Citation: Levis B, Benedetti A, Riehm KE .
Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews.
Br J Psychiatry 2018 Jun;212(6):377-85. doi: 10.1192/bjp.2018.54..
Keywords: Depression, Diagnostic Safety and Quality, Behavioral Health
Radovic A, DeMand AL, Gmelin T
SOVA: design of a stakeholder informed social media website for depressed adolescents and their parents.
This paper describes iterative stakeholder interviews conducted with adolescents, young adults, parents, advocates, and clinicians and use of human computer interaction techniques to inform major design changes for two social media website for depressed adolescents and for parents.
AHRQ-funded; HS022989.
Citation: Radovic A, DeMand AL, Gmelin T .
SOVA: design of a stakeholder informed social media website for depressed adolescents and their parents.
J Technol Hum Serv 2018;35(3):169-82. doi: 10.1080/15228835.2017.1347552..
Keywords: Children/Adolescents, Depression, Patient and Family Engagement, Social Media
Stringer KL, Azuero A, Ott C
Feasibility and acceptability of real-time antiretroviral adherence monitoring among depressed women living with HIV in the deep south of the US.
The purpose of this study was to present feasibility and acceptability data on the use of an electronic adherence monitor (EAM) among African American women in remote areas of the Southeastern United States with HIV and co-occurring depression. EAM and self-reported antiretroviral therapy (ART) adherence was monitored among 25 participants recruited at four HIV clinics in Alabama. Intra-class correlation showed a low degree of concordance between EAM and self-reported adherence. 83% of data collected via EAM was transmitted in real-time; the remainder was delayed though technological failures or was lost entirely. The authors conclude that EAM monitoring is feasible in a rural US setting but that technological difficulties may impede the device's usefulness for just-in-time adherence interventions.
AHRQ-funded; HS013852.
Citation: Stringer KL, Azuero A, Ott C .
Feasibility and acceptability of real-time antiretroviral adherence monitoring among depressed women living with HIV in the deep south of the US.
AIDS Behav 2018 May;23(5):1306-14. doi: 10.1007/s10461-018-2322-z..
Keywords: Depression, Health Information Technology (HIT), Human Immunodeficiency Virus (HIV), Medication, Behavioral Health, Patient Adherence/Compliance, Rural Health, Telehealth, Women
Kato E, Borsky AE, Zuvekas SH
AHRQ Author: Kato E, Borsky AE, Zuvekas SH, Soni A, Ngo-Metzger Q
Missed opportunities for depression screening and treatment in the United States.
This study estimates the prevalence of depression assessment in adults age 35 and older and how prevalence varies by sociodemographic characteristics and depressive symptoms. It found that approximately 50 percent of US adults aged 35+ were being assessed for depression in 2014-2015. Certain populations were more likely to be missed, including men, people over 75 years old, minorities, and the uninsured.
AHRQ-authored.
Citation: Kato E, Borsky AE, Zuvekas SH .
Missed opportunities for depression screening and treatment in the United States.
J Am Board Fam Med 2018 May-Jun;31(3):389-97. doi: 10.3122/jabfm.2018.03.170406.
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Keywords: Depression, Medical Expenditure Panel Survey (MEPS), Prevention, Screening, Social Determinants of Health
Liu CH, Phan J, Yasui M
Prenatal life events, maternal employment, and postpartum depression across a diverse population in New York City.
This study examined racial and ethnic disparities in three postpartum depression (PPDF) symptoms and identified specific predictors. Women from the New York City area completed the 2009-2011 Pregnancy Risk Assessment Monitoring System survey. White women were more likely to have PPD than African American women. Employment was also associated with PPD for white women.
AHRQ-funded; HS023007.
Citation: Liu CH, Phan J, Yasui M .
Prenatal life events, maternal employment, and postpartum depression across a diverse population in New York City.
Community Ment Health J 2018 May;54(4):410-19. doi: 10.1007/s10597-017-0171-2..
Keywords: Depression, Disparities, Pregnancy, Racial and Ethnic Minorities, Women
McCreedy EM, Weinstein BE, Chodosh J
Hearing loss: why does it matter for nursing homes?
This paper examines the impact of hearing loss on residents in nursing home settings and provides an estimate of prevalence using the Minimum Data Set (MDS v.3.0). They outline steps to mitigate hearing loss and discuss solutions that may be inexpensive and low-tech.
AHRQ-funded; HS000011.
Citation: McCreedy EM, Weinstein BE, Chodosh J .
Hearing loss: why does it matter for nursing homes?
J Am Med Dir Assoc 2018 Apr;19(4):323-27. doi: 10.1016/j.jamda.2017.12.007..
Keywords: Nursing Homes, Elderly, Quality of Life, Depression, Behavioral Health
McKernan LC, Walsh CG, Reynolds WS
Psychosocial co-morbidities in Interstitial cystitis/bladder pain syndrome (IC/BPS): a systematic review.
Psychosocial factors amplify symptoms of Interstitial Cystitis (IC/BPS). While psychosocial self-management is efficacious in other pain conditions, its impact on an IC/BPS population has rarely been studied. The objective of this review was to learn the prevalence and impact of psychosocial factors on IC/BPS, assess baseline psychosocial characteristics, and offer recommendations for assessment and treatment.
AHRQ-funded; HS022990.
Citation: McKernan LC, Walsh CG, Reynolds WS .
Psychosocial co-morbidities in Interstitial cystitis/bladder pain syndrome (IC/BPS): a systematic review.
Neurourol Urodyn 2018 Mar;37(3):926-41. doi: 10.1002/nau.23421..
Keywords: Pain, Anxiety, Depression, Behavioral Health, Patient-Centered Outcomes Research, Outcomes, Chronic Conditions
Aalsma MC, Zerr AM, Etter DJ
Physician intervention to positive depression screens among adolescents in primary care.
The objective of this study was to determine the effectiveness of computer-based screening and physician feedback to guide adolescent depression management within primary care. The investigators found that when a computer-based decision support system algorithm focused on adolescent depression and was implemented in two primary care clinics, a majority of physicians utilized screening results to guide clinical care.
AHRQ-funded; HS022681.
Citation: Aalsma MC, Zerr AM, Etter DJ .
Physician intervention to positive depression screens among adolescents in primary care.
J Adolesc Health 2018 Feb;62(2):212-18. doi: 10.1016/j.jadohealth.2017.08.023..
Keywords: Care Management, Children/Adolescents, Decision Making, Depression, Health Information Technology (HIT), Behavioral Health, Primary Care, Primary Care: Models of Care, Screening
Etter DJ, McCord A, Ouyang F
Suicide screening in primary care: use of an electronic screener to assess suicidality and improve provider follow-up for adolescents.
The purpose of this study was to assess the feasibility of using an existing computer decision support system to screen adolescent patients for suicidality and provide follow-up guidance to clinicians in a primary care setting. The authors concluded that incorporating adolescent suicide screening and provider follow-up guidance into an existing computer decision support system in primary care was feasible and well utilized by providers.
AHRQ-funded; HS022681.
Citation: Etter DJ, McCord A, Ouyang F .
Suicide screening in primary care: use of an electronic screener to assess suicidality and improve provider follow-up for adolescents.
J Adolesc Health 2018 Feb;62(2):191-97. doi: 10.1016/j.jadohealth.2017.08.026..
Keywords: Children/Adolescents, Clinical Decision Support (CDS), Decision Making, Depression, Behavioral Health, Primary Care, Screening
Dickerson JF, Feeny DH, Clarke GN
Evidence on the longitudinal construct validity of major generic and utility measures of health-related quality of life in teens with depression.
This study examined the longitudinal construct validity in the assessment of changes in depressive symptoms of widely used utility and generic health-related quality of life (HRQL) instruments in teens. Its findings support the longitudinal construct validity of included HRQL instruments for the assessment of change in depression outcomes in teens.
AHRQ-funded; HS017720.
Citation: Dickerson JF, Feeny DH, Clarke GN .
Evidence on the longitudinal construct validity of major generic and utility measures of health-related quality of life in teens with depression.
Qual Life Res 2018 Feb;27(2):447-54. doi: 10.1007/s11136-017-1728-9.
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Keywords: Children/Adolescents, Depression, Genetics, Quality of Life
Brunwasser SM, Gillham JE
Identifying moderators of response to the Penn Resiliency Program: a synthesis study.
Researchers sought to identify moderators of a cognitive-behavioral depression prevention program's effect on depressive symptoms among youth in early adolescence. Data from three randomized controlled trials of the Penn Resiliency Program (PRP) were aggregated to maximize statistical power and sample diversity. The primary analyses suggested that PRP's effects are limited to youth whose parents are unmarried.
AHRQ-funded; HS022990.
Citation: Brunwasser SM, Gillham JE .
Identifying moderators of response to the Penn Resiliency Program: a synthesis study.
Prev Sci 2018 Feb;19(Suppl 1):38-48. doi: 10.1007/s11121-015-0627-y.
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Keywords: Behavioral Health, Children/Adolescents, Depression, Patient-Centered Outcomes Research, Prevention
Hines AL, Roter D, Ghods Dinoso BK
Informed and patient-centered decision-making in the primary care visits of African Americans with depression.
This study examined the prevalence and extent of informed decision-making (IDM) and patient-centered decision-making (PCDM) in primary care visits of African Americans with depression. It concluded that the associations between IDM and PCDM with interpersonal ratings were moderated by overall patient-centeredness of the visit, which may be indicative of broader cross-cultural communication issues. Strengthening partnerships between depressed African Americans and their clinicians may improve patient-engaged decision-making.
AHRQ-funded; HS013645.
Citation: Hines AL, Roter D, Ghods Dinoso BK .
Informed and patient-centered decision-making in the primary care visits of African Americans with depression.
Patient Educ Couns 2018 Feb;101(2):233-40. doi: 10.1016/j.pec.2017.07.027.
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Keywords: Decision Making, Depression, Patient-Centered Healthcare, Primary Care, Racial and Ethnic Minorities
Joyce NR, Schuler MS, Hadland SE
Variation in the 12-month treatment trajectories of children and adolescents after a diagnosis of depression.
The purpose of this longitudinal cohort study was to characterize heterogeneity in 12-month trajectories of psychotherapy and antidepressant treatment in youths with depression. The investigators examined variation in baseline health, health care utilization, and health outcomes across classes with similar patterns of psychotherapy and antidepressant use.
AHRQ-funded; HS022998.
Citation: Joyce NR, Schuler MS, Hadland SE .
Variation in the 12-month treatment trajectories of children and adolescents after a diagnosis of depression.
JAMA Pediatr 2018 Jan;172(1):49-56. doi: 10.1001/jamapediatrics.2017.3808..
Keywords: Depression, Children/Adolescents, Behavioral Health, Medication
Hantsoo L, Criniti S, Khan A
A mobile application for monitoring and management of depressed mood in a vulnerable pregnant population.
The researchers tested whether a mood tracking and alert (MTA) mobile application (app) improved mental health care delivery in a high-risk obstetric population. They found that a mobile MTA app improved service delivery and patient engagement among patients with perinatal depression symptoms.
AHRQ-funded; HS022441.
Citation: Hantsoo L, Criniti S, Khan A .
A mobile application for monitoring and management of depressed mood in a vulnerable pregnant population.
Psychiatr Serv 2018 Jan;69(1):104-07. doi: 10.1176/appi.ps.201600582.
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Keywords: Healthcare Delivery, Depression, Pregnancy, Telehealth, Vulnerable Populations
DeWaters AL, Chansard M, Anzueto A
The association between major depressive disorder and outcomes in older veterans hospitalized with pneumonia.
The aim of this study was to examine the association between depression and outcomes, including mortality and intensive care unit admission, in veterans hospitalized with pneumonia. It found that patients with untreated depression had a significantly higher 30-day and 90-day mortality, as well as significantly higher intensive care unit admission rates, compared to patients with treated depression.
AHRQ-funded; HS022418.
Citation: DeWaters AL, Chansard M, Anzueto A .
The association between major depressive disorder and outcomes in older veterans hospitalized with pneumonia.
Am J Med Sci 2018 Jan;355(1):21-26. doi: 10.1016/j.amjms.2017.08.015.
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Keywords: Depression, Hospitalization, Patient-Centered Outcomes Research, Pneumonia